Catalog No.
PHJ30401
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human NEU4 (Tyr22-Pro286).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Sialidase-4,NEU4,N-acetyl-alpha-neuraminidase 4
Purification
Purified by antigen affinity column.
Accession
Q8WWR8
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Increased sialidase activity in serum of cancer patients: Identification of sialidase and inhibitor activities in human serum., PMID:25652216
Molecular cloning and biochemical characterization of medaka (Oryzias latipes) lysosomal neu4 sialidase., PMID:24744226
A novel insulin receptor-signaling platform and its link to insulin resistance and type 2 diabetes., PMID:24583283
Expression of the infectious salmon anemia virus receptor on atlantic salmon endothelial cells correlates with the cell tropism of the virus., PMID:22811536
Sialidase NEU4 hydrolyzes polysialic acids of neural cell adhesion molecules and negatively regulates neurite formation by hippocampal neurons., PMID:22393058
Thymoquinone from nutraceutical black cumin oil activates Neu4 sialidase in live macrophage, dendritic, and normal and type I sialidosis human fibroblast cells via GPCR Galphai proteins and matrix metalloproteinase-9., PMID:20213245
Human sialidase as a cancer marker., PMID:18651674
Monocyte differentiation up-regulates the expression of the lysosomal sialidase, Neu1, and triggers its targeting to the plasma membrane via major histocompatibility complex class II-positive compartments., PMID:16835219
Differential expression of endogenous sialidases of human monocytes during cellular differentiation into macrophages., PMID:15885103
Molecular cloning and characterization of NEU4, the fourth member of the human sialidase gene family., PMID:14962670
Expression of Neural Antigens in Normal Xenopus Embryos and Induced Explants: (Xenopus laevis/neural antigens/monoclonal antibodies/neural induction/neural differentiation)., PMID:37280931
For research use only. Not for human or drug use.
