Catalog No.
YHD27202
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly28-Lys291
Predicted molecular weight
31.04 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P17936
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
IBP-3, Insulin-like growth factor-binding protein 3, IGF-binding protein 3, IBP3, IGFBP-3, IGFBP3
Note
For research use only.
Effects of recombinant human growth hormone injection combined with Anastrozole on height and growth rate of adolescent idiopathic short stature and evaluation of adverse reactions., PMID:39799442
Identification of IGFBP3 and LGALS1 as potential secreted biomarkers for clear cell renal cell carcinoma based on bioinformatics analysis and machine learning., PMID:39807607
Insulin and Insulin-like Growth Factor and Risk of Postmenopausal Estrogen Receptor-Positive Breast Cancer: A Case-Cohort Analysis., PMID:39808164
Exploring the mechanism of rosmarinic acid in the treatment of lung adenocarcinoma based on bioinformatics methods and experimental validation., PMID:39812944
HDAC3 and Snail2 complex promotes melanoma metastasis by epigenetic repression of IGFBP3., PMID:39864688
Comparison of growth hormone therapy response according to the presence of growth hormone deficiency in children born small for gestational age with short stature in Korea: a retrospective cohort study., PMID:39893395
Neutrophil-to-lymphocyte ratio is associated with accelerometer-measured physical activity levels in breast cancer survivors., PMID:39939471
The Effects of a Novel Astragalus-Based Extract (Keyfobell Powder (KFB)) on Longitudinal Bone Growth via IGF-1 Upregulation: A Potential Growth Hormone Alternative., PMID:39940274
Absence of genetic association between insulin-like growth factors and esophageal cancer., PMID:39969361
Efficacy of Naringenin against aging and degeneration of nucleus pulposus cells through IGFBP3 inhibition., PMID:40000729
The mechanism of high mobility group box-1 in the proliferation and macrophage polarization in esophageal squamous cell carcinoma cells., PMID:40022250
Exploring the Plasma Proteome: Identifying Hub Proteins linking Aging, Homeostasis, and Organ Function., PMID:40027189
Antibodies against the receptor for insulin-like growth factor 1 (IGF-1RAb), insulin-like growth factor 1 (IGF-1), and insulin-like growth factor binding protein 3 (IGFBP-3) in the serum of patients with Graves' and Basedow's disease with and without orbitopathy., PMID:40071798
Circ_0044362 Facilitates the Progression of Epithelial Ovarian Cancer via Enhancing HOXB4 Transcription to Activate the RUNX1/IGFBP3 Axis., PMID:40099691
IGF1 Signaling Regulates Neuropeptide Expression in Hypothalamic Neurons Under Physiological and Pathological Conditions., PMID:40105689
TBK1 is a signaling hub in coordinating stress-adaptive mechanisms in head and neck cancer progression., PMID:40114316
Targeted proteomics of serum IGF-I, -II, IGFBP-2, -3, -4, -5, -6 and ALS., PMID:40116411
Aregs-IGFBP3-mediated SMC-like cells apoptosis impairs beige adipocytes formation in aged mice., PMID:40118146
Pharmacodynamics, pharmacokinetics, and toxicology of Fc-growth hormone fusion protein in macaques., PMID:40120208
Associations between Serum Insulin-Like Growth Factor-Related Molecules and Colorectal Cancer Risk by Tumor Location: A Nested Case-Control Study., PMID:40132573
PromarkerD Versus Standard of Care Biochemical Measures for Assessing Future Renal Function Decline in Type 2 Diabetes., PMID:40150005
Role of Quercetin in Modulating Inflammation and Epigenetic Regulation of Staphylococcus aureus-Induced Bovine Mastitis., PMID:40168353
Insulin-like growth factor binding protein-3 (IGFBP-3): a biomarker of coronary artery disease induced myocardial ischaemia., PMID:40177504
Expression of Salivary and Serum IGF-1 and IGFBP-3 in Individuals With Diabetes and Oral Cancer., PMID:40182453
Associations of circulating insulin-like growth factor-1 and insulin-like growth factor binding protein-3 with the expression of stem cell markers in benign breast tissue., PMID:40197284
Role of IGFBP-3 in Human Diseases Relying on Different Cell Signaling Pathways., PMID:40213590
Changes in the expression pattern of genes affecting the growth and development of mammary tissue in pregnant Saanen goats in response to dietary fats., PMID:40215566
Feasibility, safety, and efficacy of high-dose intermittent theta burst stimulation in children with autism spectrum disorder: study protocol for a pilot randomized sham-controlled trial., PMID:40230821
Markers for the angiogenic potential of fat grafts., PMID:40232500
X-ray-Sensitive Selenium Nanoparticles Enhance Esophageal Squamous Cell Carcinoma Radiotherapy through Activating P53/IGFBP3 Pathway by Regulating GPX2., PMID:40241246
Research progress on ADAM28 in malignant tumors., PMID:40252142
Early warning value of multiple serum indicators combined with ultrasound detection in girls with central precocious puberty., PMID:40260284
Predictive Effect of IGFBP-3 on Low-Dose Tamoxifen Efficacy in Noninvasive Breast Cancer in the Phase III Tam-01 Trial., PMID:40293268
MRI-Based Evaluation of Pituitary Size and Volume in Children with Idiopathic Growth Hormone Deficiency., PMID:40326894
Soluble alpha klotho-impact of biological variables and reference intervals for adults., PMID:40338072
IGFBP3 enhances adipose-derived stem cell function in soft tissue injury repair via ITGB1 and ERK pathway activation., PMID:40369223
Association of serum insulin-like growth factor-1 and adrenocorticotropic hormone therapeutic response in patients with infantile epileptic spasms syndrome., PMID:40371354
TMEM219 signaling promotes intestinal stem cell death and exacerbates colitis., PMID:40371646
Humulus japonicus Enhances Bone Growth and Microarchitecture in Rats: Potential Involvement of IGF-1 Signaling., PMID:40372960
The influence of gender-affirming hormone therapy on serum concentrations of hormone-binding proteins., PMID:40377124
New Gene Targets for Diagnosis and Therapy of Diabetic Retinopathy., PMID:40377287
Potential diagnostic marker gene set for non-alcoholic steatohepatitis associated hepatocellular carcinoma with lymphocyte infiltration., PMID:40386252
DBI as a Novel Immunotherapeutic Candidate in Colorectal Cancer: Dissecting Genetic Risk and the Immune Landscape via GWAS, eQTL, and pQTL., PMID:40426943
Aerobic exercise alleviates chronic allergic airway inflammation by regulating the circMETTL9/EIF4A3/IGFBP3 axis., PMID:40436287
Correlation of Body Mass Index with Serum Osteocalcin and Insulin-Like Growth Factor Binding Protein-3 in the Assessment of Pubertal Growth Spurt - A Comparative Study., PMID:40439207
Xanthosomes loaded with recombinant TMEM219 for targeting IGFBP-3: A novel approach for targeted drug delivery to ameliorate liver fibrosis., PMID:40447257
Controllable nickel ions release from deferoxamine mesylate-triggered nickel-iron layered double hydroxide for eliciting apoptotic cell death in prostate cancer., PMID:40448082
Chromatin architecture protein HMGA2 promotes glioma malignancy via novel mechanism of IGFBP3 transcription inhibition., PMID:40450974
Impact of IGFBP-3 A-202C genetic variant on breast cancer susceptibility and serum biomarkers (IGFBP-3 and IGF-1) in Palestinian women., PMID:40493660
IGFBP3 modulation of tumor pathogenesis and cell signaling pathways (Review)., PMID:40503041