Anti-PIK3C3 Polyclonal Antibody

Catalog No.

PHJ24501

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human PIK3C3 (Tyr631-Trp885).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

PtdIns-3-kinase type 3,Phosphatidylinositol 3-kinase p100 subunit,hVps34,Phosphatidylinositol 3-kinase catalytic subunit type 3,Phosphoinositide-3-kinase class 3,PI3-kinase type 3,VPS34,PI3K type 3,PIK3C3

Purification

Purified by antigen affinity column.

Accession

Q8NEB9

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Pik3c3 expression profiling in the mouse kidney and its role in proximal tubule cell physiology., PMID:39250817

Genome-wide CRISPR/Cas9 screen identifies SLC39A9 and PIK3C3 as crucial entry factors for Ebola virus infection., PMID:39173055

Thymic epithelial cells require lipid kinase Vps34 for CD4 but not CD8 T cell selection., PMID:35997680

Platelet autophagic machinery involved in thrombosis through a novel linkage of AMPK-MTOR to sphingolipid metabolism., PMID:33749503

Neutrophil autophagy during human active tuberculosis is modulated by SLAMF1., PMID:32954947

PDPK1 regulates autophagosome biogenesis by binding to PIK3C3., PMID:32876514

PKD2/polycystin-2 induces autophagy by forming a complex with BECN1., PMID:32543276

Binding of Avibirnavirus VP3 to the PIK3C3-PDPK1 complex inhibits autophagy by activating the AKT-MTOR pathway., PMID:31885313

Emerging views of mitophagy in immunity and autoimmune diseases., PMID:30951392

Morphological characterization of Class III phosphoinositide 3-kinase during mouse brain development., PMID:26242203

The human CD5L/AIM-CD36 axis: A novel autophagy inducer in macrophages that modulates inflammatory responses., PMID:25713983

Promoter variant of PIK3C3 is associated with autoimmunity against Ro and Sm epitopes in African-American lupus patients., PMID:20671926

Deletion of PIK3C3/Vps34 in sensory neurons causes rapid neurodegeneration by disrupting the endosomal but not the autophagic pathway., PMID:20439739

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