Catalog No.
PMN42401
Species reactivity
Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Mouse CLEC4E (Glu65-Asp214).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
C-type lectin superfamily member 9, Macrophage-inducible C-type lectin, MINCLE, CLECSF9, CLEC4E, C-type lectin domain family 4 member E
Purification
Purified by antigen affinity column.
Accession
Q9R0Q8
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
IL-33, a neutrophil extracellular trap-related gene involved in the progression of diabetic kidney disease., PMID:39797951
C-type lectin receptor expression is a hallmark of neutrophils infiltrating the skin in epidermolysis bullosa acquisita., PMID:37799716
Characterisation of the bovine C-type lectin receptor Mincle and potential evidence for an endogenous ligand., PMID:37275870
Proteomic analysis of liver tissue reveals Aeromonas hydrophila infection mediated modulation of host metabolic pathways in Labeo rohita., PMID:36906258
Acute systemic myeloid inflammatory and stress response in severe food allergic reactions., PMID:36756745
Escherichia coli-derived outer-membrane vesicles induce immune activation and progression of cirrhosis in mice and humans., PMID:36751961
C-type lectin Mincle-dependent and -independent activation of invariant NKT cells by exposure to Helicobacter pylori α-cholesteryl glucosides., PMID:35920835
Mincle-binding DNA aptamer demonstrates therapeutic potential in a model of inflammatory bowel disease., PMID:35782912
Recognition of Tumor Nidogen-1 by Neutrophil C-Type Lectin Receptors., PMID:35453656
Pathogenic TNF-α drives peripheral nerve inflammation in an Aire-deficient model of autoimmunity., PMID:35058362
Expression and regulation of macrophage-inducible C-type lectin in human synovial macrophages., PMID:33613092
Microglial Mincle receptor in the PVN contributes to sympathetic hyperactivity in acute myocardial infarction rat., PMID:30353660
Mincle: 20 years of a versatile sensor of insults., PMID:29726997
Mycobacterial receptor, Clec4d (CLECSF8, MCL), is coregulated with Mincle and upregulated on mouse myeloid cells following microbial challenge., PMID:26558717
C-type lectin receptor dectin-3 mediates trehalose 6,6'-dimycolate (TDM)-induced Mincle expression through CARD9/Bcl10/MALT1-dependent nuclear factor (NF)-κB activation., PMID:25202022
Evaluation of the contribution of multiple DAMPs and DAMP receptors in cell death-induced sterile inflammatory responses., PMID:25127469
Characterization of the receptors for mycobacterial cord factor in Guinea pig., PMID:24533147
Silencing of renal DNaseI in murine lupus nephritis imposes exposure of large chromatin fragments and activation of Toll like receptors and the Clec4e., PMID:22479529
Effect of infliximab on gene expression profiling in Behcet's disease., PMID:21862654