Please ensure Javascript is enabled for purposes of website accessibility
Home / Products / Antibody / Polyclonal Antibody

Anti-Mouse CD258/TNFSF14/LIGHT Polyclonal Antibody

Catalog #:   PMA70801 Specific References (37) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q9QYH9
Overview

Catalog No.

PMA70801

Species reactivity

Mouse

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Mouse CD258/TNFSF14/LIGHT (Asp72-Val239).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Herpes virus entry mediator ligand, LIGHT, CD258, HVEM-L, HVEML, TNFSF14, Tumor necrosis factor ligand superfamily member 14, Herpesvirus entry mediator ligand

Purification

Purified by antigen affinity column.

Accession

Q9QYH9

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
References

Randomized, double-blind, controlled trial of human anti-LIGHT monoclonal antibody in COVID-19 acute respiratory distress syndrome., PMID:34871182

Levels of the TNF-Related Cytokine LIGHT Increase in Hospitalized COVID-19 Patients with Cytokine Release Syndrome and ARDS., PMID:32817460

Shedding "LIGHT" on the Link between Bone and Fat in Obese Children and Adolescents., PMID:32635185

Unique Sjögren's syndrome patient subsets defined by molecular features., PMID:31497844

LIGHT/TNFSF14 as a New Biomarker of Bone Disease in Multiple Myeloma Patients Experiencing Therapeutic Regimens., PMID:30405638

LIGHT-HVEM signaling in keratinocytes controls development of dermatitis., PMID:29339444

DcR3 promotes hepatoma cell migration by downregulating E-cadherin expression., PMID:28560426

Skewing toward Treg and Th2 responses is a characteristic feature of sustained remission in ANCA-positive granulomatosis with polyangiitis., PMID:28155222

A Randomized Phase 1 Study to Assess the Safety and Pharmacokinetics of the Subcutaneously Injected Anti-LIGHT Antibody, SAR252067., PMID:27545119

The Tumor Necrosis Factor Superfamily Molecule LIGHT Promotes Keratinocyte Activity and Skin Fibrosis., PMID:25789702

Therapeutic blockade of LIGHT interaction with herpesvirus entry mediator and lymphotoxin β receptor attenuates in vivo cytotoxic allogeneic responses., PMID:25226173

Reverse signaling from LIGHT promotes pro-inflammatory responses in the human monocytic leukemia cell line, THP-1., PMID:24044961

Serum-soluble herpes virus entry mediator levels reflect disease severity and Th2 environment in cutaneous T-cell lymphoma., PMID:23306973

Molecular basis for herpesvirus entry mediator recognition by the human immune inhibitory receptor CD160 and its relationship to the cosignaling molecules BTLA and LIGHT., PMID:21959263

Characterization of herpes virus entry mediator as a factor linked to obesity., PMID:19680232

From gene expression to serum proteins: biomarker discovery in ankylosing spondylitis., PMID:19103635

Platelet-associated LIGHT (TNFSF14) mediates adhesion of platelets to human vascular endothelium., PMID:17938804

Targeting lymphotoxin beta receptor with tumor-specific T lymphocytes for tumor regression., PMID:17785576

LIGHT up-regulated on B lymphocytes and monocytes in rheumatoid arthritis mediates cellular adhesion and metalloproteinase production by synoviocytes., PMID:17393389

Recruitment and activation of naive T cells in the islets by lymphotoxin beta receptor-dependent tertiary lymphoid structure., PMID:16934497

LIGHT (TNFSF14), a novel mediator of bone resorption, is elevated in rheumatoid arthritis., PMID:16649193

Inhibition of lymphotoxin-beta receptor-mediated cell death by survivin-DeltaEx3., PMID:16540654

LIGHT enhances the bactericidal activity of human monocytes and neutrophils via HVEM., PMID:16275888

LIGHT costimulates CD40 triggering and induces immunoglobulin secretion; a novel key partner in T cell-dependent B cell terminal differentiation., PMID:15549770

Attenuation of graft arterial disease by manipulation of the LIGHT pathway., PMID:15178556

[Eukaryotic expression of human LIGHT-Fc chimeric molecule and its anti-tumor activity]., PMID:15169669

The effect of LIGHT in inducing maturation of monocyte-derived dendritic cells from MDS patients., PMID:15103504

Dysregulated LIGHT expression on T cells mediates intestinal inflammation and contributes to IgA nephropathy., PMID:15067315

A role for the lymphotoxin/LIGHT axis in the pathogenesis of murine collagen-induced arthritis., PMID:12816989

The role of apoptosis signal-regulating kinase 1 in lymphotoxin-beta receptor-mediated cell death., PMID:12566458

LIGHT, a new member of the TNF superfamily., PMID:12456019

Mouse T cells receive costimulatory signals from LIGHT, a TNF family member., PMID:12384428

Recombinant, soluble LIGHT (HVEM ligand) induces increased IL-8 secretion and growth arrest in A375 melanoma cells., PMID:11429164

The three HveA receptor ligands, gD, LT-alpha and LIGHT bind to distinct sites on HveA., PMID:11164894

LIGHT, a TNF-like molecule, costimulates T cell proliferation and is required for dendritic cell-mediated allogeneic T cell response., PMID:10754304

Costimulatory wars: the tumor menace., PMID:11007364

Modulation of T-cell-mediated immunity in tumor and graft-versus-host disease models through the LIGHT co-stimulatory pathway., PMID:10700230

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

Contact Information

Order: order@antibodysystem.com

Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

Need help with your order?

Find out more about placing an order here

Anti-Mouse CD258/TNFSF14/LIGHT Polyclonal Antibody [PMA70801]
Terms of sale Website terms of use Cookie policy Privacy
Copyright © 2025 AntibodySystem SAS. All Rights Reserved.            All Products are for Research Use Only