Catalog No.
PMN41201
Species reactivity
Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Mouse Mgl2 (His192-Leu316).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:200, WB: 1:500-1:4000
Target
Macrophage galactose N-acetyl-galactosamine specific lectin 2, Macrophage galactose-type C-type lectin 2, Mgl2
Concentration
0.53 mg/ml
Purification
Purified by antigen affinity column.
Accession
Q8JZN1
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fluoxetine rescues the depressive-like behaviour induced by reserpine and the altered emotional behaviour induced by nicotine withdrawal in zebrafish: Involvement of tyrosine hydroxylase., PMID:37593958
Type 2 immunity plays an essential role for murine model of allergic contact dermatitis with mixed type 1/type 2 immune response., PMID:34763990
The Tn antigen promotes lung tumor growth by fostering immunosuppression and angiogenesis via interaction with Macrophage Galactose-type lectin 2 (MGL2)., PMID:34144098
CD301 mediates fusion in IL-4-driven multinucleated giant cell formation., PMID:33571108
Knockdown of milk-fat globule EGF factor-8 suppresses glioma progression in GL261 glioma cells by repressing microglial M2 polarization., PMID:32324268
Enhanced Immune Response Against the Thomsen-Friedenreich Tumor Antigen Using a Bivalent Entirely Carbohydrate Conjugate., PMID:32183149
Macrophage galactose lectin is critical for Kupffer cells to clear aged platelets., PMID:31978220
Modulating Macrophage Polarization through CCR2 Inhibition and Multivalent Engagement., PMID:29791797
CD301b/MGL2+ Mononuclear Phagocytes Orchestrate Autoimmune Cardiac Valve Inflammation and Fibrosis., PMID:29386201
Effect of Porphyromonas gingivalis infection in the placenta and umbilical cord in pregnant mice with low birth weight., PMID:29334319
GalNAc-Tyrosine Is a Ligand of Plant Lectins, Antibodies, and Human and Murine Macrophage Galactose-Type Lectins., PMID:28644609
CD301b+ Macrophages Are Essential for Effective Skin Wound Healing., PMID:27287183
A unique dermal dendritic cell subset that skews the immune response toward Th2., PMID:24039898
Distribution and function of macrophage galactose-type C-type lectin 2 (MGL2/CD301b): efficient uptake and presentation of glycosylated antigens by dendritic cells., PMID:20304916
The dermal microenvironment induces the expression of the alternative activation marker CD301/mMGL in mononuclear phagocytes, independent of IL-4/IL-13 signaling., PMID:16849611
Retardation of removal of radiation-induced apoptotic cells in developing neural tubes in macrophage galactose-type C-type lectin-1-deficient mouse embryos., PMID:16096344
Lack of antigen-specific tissue remodeling in mice deficient in the macrophage galactose-type calcium-type lectin 1/CD301a., PMID:15784728
Molecular cloning and characterization of a novel mouse macrophage C-type lectin, mMGL2, which has a distinct carbohydrate specificity from mMGL1., PMID:12016228
For research use only. Not for human or drug use.
