Anti-Mouse CLU Polyclonal Antibody

Catalog No.

PMC84101

Species reactivity

Mouse

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Mouse CLU (Lys380-Glu448).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

APOJ, ApoJalpha, NA1/NA2, Complement cytolysis inhibitor, Complement cytolysis inhibitor a chain, Ku70-binding protein 1, Testosterone-repressed prostate message 2, ApoJbeta, TRPM-2, Complement cytolysis inhibitor b chain, SGP-2, KUB1, Apolipoprotein J, Apo-J, Clusterin, Sulfated glycoprotein 2, Aging-associated gene 4 protein, CLI, CLU, Complement-associated protein SP-40,40

Purification

Purified by antigen affinity column.

Accession

Q06890

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Tracking clusterin expression in hematopoietic stem cells reveals their heterogeneous composition across the lifespan., PMID:40132120

The Platelet-Specific Gene Signature in the Immunoglobulin G4-Related Disease Transcriptome., PMID:39859144

Targeting immune checkpoints on myeloid cells: current status and future directions., PMID:39751898

A non-invasive model for diagnosis of primary Sjogren's disease based on salivary biomarkers, serum autoantibodies, and Schirmer's test., PMID:39695856

Complement C7 and clusterin form a complex in circulation., PMID:38333209

First Data on Ornithodoros moubata Aquaporins: Structural, Phylogenetic and Immunogenic Characterisation as Vaccine Targets., PMID:35745548

A comprehensive molecular approach in fish allergy: Usefulness in daily clinical practice., PMID:35716706

Proteomic Insight into the Role of Exosomes in Proliferative Vitreoretinopathy Development., PMID:35628842

Potential participation of CTRP6, a complement regulator, in the pathology of age related macular degeneration., PMID:35397057

Complement Inhibitors Vitronectin and Clusterin Are Recruited from Human Serum to the Surface of Coronavirus OC43-Infected Lung Cells through Antibody-Dependent Mechanisms., PMID:35062233

Changes in Expression of Specific mRNA Transcripts after Single- or Re-Irradiation in Mouse Testes., PMID:35052491

Genomics of Alzheimer's disease implicates the innate and adaptive immune systems., PMID:34708251

Serum Clusterin Level Could Reflect the Current Activity of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis., PMID:34672135

Clusterin enhances cell survival by suppressing neuronal nitric-oxide synthase expression in the rhodopsin S334ter-line3 retinitis pigmentosa model., PMID:34242654

The Anti-HER3 mAb Seribantumab Effectively Inhibits Growth of Patient-Derived and Isogenic Cell Line and Xenograft Models with Oncogenic NRG1 Fusions., PMID:33824166

Discovery and validation of FBLN1 and ANT3 as potential biomarkers for early detection of cervical cancer., PMID:33602229

Clusterin Deficiency Predisposes C57BL/6j Mice to Cationic Bovine Serum Albumin-Induced Glomerular Inflammation., PMID:33262633

Chronic treatment with the (iso-)glutaminyl cyclase inhibitor PQ529 is a novel and effective approach for glomerulonephritis in chronic kidney disease., PMID:33159802

Silencing of NAMPT leads to up-regulation of insulin receptor substrate 1 gene expression in U87 glioma cells., PMID:32597148

A Path Toward Precision Medicine for Neuroinflammatory Mechanisms in Alzheimer's Disease., PMID:32296418

Colorimetric Paper-Based Immunosensor for Simultaneous Determination of Fetuin B and Clusterin toward Early Alzheimer's Diagnosis., PMID:31661258

Differential effects of apoE and apoJ mimetic peptides on the action of an anti-Aβ scFv in 3xTg-AD mice., PMID:30026023

Development of a Label-Free Immunosensor for Clusterin Detection as an Alzheimer's Biomarker., PMID:29361679

Expression of clusterin in colorectal carcinoma in relation to clinicopathological criteria., PMID:29279586

Inhibiting the Ca2+ Influx Induced by Human CSF., PMID:29241555

Effects of an Aβ-antibody fragment on Aβ aggregation and astrocytic uptake are modulated by apolipoprotein E and J mimetic peptides., PMID:29155887

Downregulation of Apolipoprotein-E and Apolipoprotein-J in Moyamoya Disease-A Proteome Analysis of Cerebrospinal Fluid., PMID:28843803

Spatiotemporal expression patterns of clusterin in the mouse inner ear., PMID:28687930

A Preliminary Study: PS1 Increases U1 snRNA Expression Associated with AD., PMID:28577205

Secretion modification region-derived peptide blocks exosome release and mediates cell cycle arrest in breast cancer cells., PMID:28076321

Toll-like receptor 4 signaling is required for clusterin-induced tumor necrosis factor-α secretion in macrophage., PMID:27965092

The emerging roles of clusterin on reduction of both blood retina barrier breakdown and neural retina damage in diabetic retinopathy., PMID:27232509

Serum Clusterin as a Prognostic Marker of Chronic Spontaneous Urticaria., PMID:27175709

Clusterin facilitates apoptotic cell clearance and prevents apoptotic cell-induced autoimmune responses., PMID:27148688

Clusterin Binds to Aβ1-42 Oligomers with High Affinity and Interferes with Peptide Aggregation by Inhibiting Primary and Secondary Nucleation., PMID:26884339

Clusterin, a gene enriched in intestinal stem cells, is required for L1-mediated colon cancer metastasis., PMID:26399194

Clusterin/Apolipoprotein J immunoreactivity is associated with white matter damage in cerebral small vessel diseases., PMID:25940137

Evaluation of vaccine seroresponse rates and adverse event rates through Bayesian and frequentist methods., PMID:25909683

Role of an extracellular chaperone, Clusterin in the pathogenesis of Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma., PMID:25057782

Clusterin expression in gastrointestinal neuroendocrine tumours is highly correlated with location and is helpful in determining the origin of liver metastases., PMID:24807631

A multimarker panel for circulating tumor cells detection predicts patient outcome and therapy response in metastatic colorectal cancer., PMID:24752533

Diagnostic evaluation of urinary angiogenin (ANG) and clusterin (CLU) as biomarker for bladder cancer., PMID:24696417

Identification and validation of novel candidate protein biomarkers for the detection of human gastric cancer., PMID:24512919

Syndecan-1 knockdown in endometrial epithelial cells alters their apoptotic protein profile and enhances the inducibility of apoptosis., PMID:24478463

Far-infrared radiation inhibits proliferation, migration, and angiogenesis of human umbilical vein endothelial cells by suppressing secretory clusterin levels., PMID:24334140

Quantification of clusterin in paired cerebrospinal fluid and plasma samples., PMID:24146185

Plasma clusterin concentrations may predict resistance to intravenous immunoglobulin in patients with Kawasaki disease., PMID:23956692

Aspirin insensitive thrombophilia: transcript profiling of blood identifies platelet abnormalities and HLA restriction., PMID:23454623

Protective role of clusterin in preserving endothelial function in AL amyloidosis., PMID:22981431

Germline variation in complement genes and event-free survival in follicular and diffuse large B-cell lymphoma., PMID:22718493

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