Catalog No.
PME23901
Species reactivity
Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Mouse COL18A1 (Glu491-Lys678).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
NC1, COL18A1, Collagen alpha-1(XVIII) chain
Purification
Purified by antigen affinity column.
Accession
P39061
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Sintilimab + Nab-PP Combined with Recombinant Human Vascular Endothelial Inhibitor for Locally Advanced/Advanced and Recurrent Metastatic Squamous Non-Small Cell Lung Cancer: Study Protocol for a Single-Arm, Multi-Centre Phase II Clinical Study., PMID:40415559
Gut microbiome influences efficacy of Endostatin combined with PD-1 blockade against colorectal cancer., PMID:39251538
Tofacitinib Regulates Endostatin via Effects on CD147 and Cathepsin S., PMID:39000375
Immunotherapy combined with antiangiogenic therapy as third- or further-line therapy for stage IV non-small cell lung cancer patients with ECOG performance status 2: A retrospective study., PMID:38872402
Soluble CD147 regulates endostatin via its effects on the activities of MMP-9 and secreted proteasome 20S., PMID:38318187
Antibody-Drug Conjugate αEGFR-E-P125A Reduces Triple-negative Breast Cancer Vasculogenic Mimicry, Motility, and Metastasis through Inhibition of EGFR, Integrin, and FAK/STAT3 Signaling., PMID:38315147
Recombinant human endostatin as a potential anti-angiogenic agent: therapeutic perspective and current status., PMID:38123873
A real-world study of recombinant human endostatin combined with PD-1/PD-L1 blockade and chemotherapy for patients with advanced non-small cell lung cancer negative for actionable molecular biomarkers., PMID:37832095
Quantification of extracellular matrix remodeling for the non-invasive identification of graft fibrosis after liver transplantation., PMID:37055472
Proteomic aptamer analysis reveals serum markers that characterize preclinical systemic sclerosis (SSc) patients at risk for progression toward definite SSc., PMID:36707842
Rh-endostatin plus camrelizumab and chemotherapy in first-line treatment of advanced non-small cell lung cancer: A multicenter retrospective study., PMID:36494905
Evaluating the efficacy and microenvironment changes of HER2 + gastric cancer during HLX02 and Endostar treatment using quantitative MRI., PMID:36192709
Comparative proteomic analysis of glomerular proteins in primary and bucillamine-induced membranous nephropathy., PMID:35836124
Analysis of cardio-cerebrovascular adverse events in patients with brain metastasis from lung cancer treated with antiangiogenic drugs., PMID:35221276
Tolerance and Pharmacokinetics of Recombinant Human Endostatin Administered as Single-Dose or Multiple-Dose Infusions in Patients With Advanced Solid Tumors: A Phase I Clinical Trial., PMID:34931914
Study on the clinical effects of targeted therapy on elderly patients with gastric cancer., PMID:34862871
Inhibitory effects of icotinib combined with antiangiogenic drugs in human non-small cell lung cancer xenograft models are better than single target drugs., PMID:34855286
Inhibition of Vasculogenic Mimicry and Angiogenesis by an Anti-EGFR IgG1-Human Endostatin-P125A Fusion Protein Reduces Triple Negative Breast Cancer Metastases., PMID:34831127
A rapid response of lung squamous cell carcinoma following treatment with sintilimab combined with recombinant humane endostatin injection and nab-paclitaxel in an elderly patient: A case report., PMID:34397833
Comparison of endostatin combined with PT-DC versus bevacizumab combined with PT-DC in the first-line treatment of advanced lung adenocarcinoma: a retrospective propensity score-matched cohort study., PMID:34353072
Elevated Levels of Endoglin, Endostatin, FGF-α, HGF, and Thrombospondin-2 in Aqueous Humor of nAMD Patients., PMID:33793358
Novel therapies for malignant pleural effusion: Anti‑angiogenic therapy and immunotherapy (Review)., PMID:33650668
Pretreatment to Posttreatment Hypoxia Inducible Factor-1α Ratios as a Potentially Predictive Marker for First-Line Treatment in Nonsmall Cell Lung Cancer Patients without Known Driver Mutations., PMID:33347392
Elevated Endostatin Expression Is Regulated by the pIgA Immune Complex and Associated with Disease Severity of IgA Nephropathy., PMID:33341801
Synergic effect of PD-1 blockade and endostar on the PI3K/AKT/mTOR-mediated autophagy and angiogenesis in Lewis lung carcinoma mouse model., PMID:32106386
A Protein Microarray Analysis of Plasma Proteins for the Prediction of Spontaneous Preterm Delivery in Women with Preterm Labor., PMID:32046457
Effect of endostatin overexpression on angiotensin II-induced cardiac hypertrophy in rats., PMID:31725448
Type XVIII Collagen Modulates Keratohyalin Granule Formation and Keratinization in Oral Mucosa., PMID:31554264
Validation of an enzyme-linked immunosorbent assay (ELISA) for quantification of endostatin levels in mice as a biomarker of developing glomerulonephritis., PMID:31404120
Anti-Tumor Activity and Pharmacokinetics of AP25-Fc Fusion Protein., PMID:31341417
Comparison of efficacy and toxicity of bevacizumab, endostar and apatinib in transgenic and human lung cancer xenograftzebrafish model., PMID:30367145
A Retrospective Study to Compare Five Induction Chemotherapy Regimens Prior to Radiotherapy in the Reduction of Regional Lymph Node Size in Patients with Nasopharyngeal Carcinoma., PMID:29697098
Circulating Vascular Basement Membrane Fragments are Associated with the Diameter of the Abdominal Aorta and Their Expression Pattern is Altered in AAA Tissue., PMID:29656960
A pre-clinical safety study of PEGylated recombinant human endostatin (M2ES) in Sprague Dawley rats., PMID:29580973
Efficient targeted tumor imaging and secreted endostatin gene delivery by anti-CD105 immunoliposomes., PMID:29499713
Collagen XVIII: A key interfacial component of the skin architecture., PMID:29465380
The endothelial specific isoform of type XVIII collagen correlates to annual bleeding rate in haemophilia patients., PMID:29320534
Mediators of angiogenesis and fibrosis in IgG4-related disease., PMID:29243036
Blood biomarkers in a mouse model of CADASIL., PMID:27174004
[Antiangiogenic drugs enhance the ability of invasion and metastasis of breast cancer cells under serum starvation and hypoxia]., PMID:26462887
Combined Anti-PLGF and Anti-Endostatin Treatments Inhibit Ocular Hemangiomas., PMID:26088746
Extension of the in vivo half-life of endostatin and its improved anti-tumor activities upon fusion to a humanized antibody against tumor-associated glycoprotein 72 in a mouse model of human colorectal carcinoma., PMID:25762629
Letter to the Editor: Fusion antibody Fc-endostatin., PMID:25723300
Targeted antiangiogenesis gene therapy using targeted cationic microbubbles conjugated with CD105 antibody compared with untargeted cationic and neutral microbubbles., PMID:25699099
A Gelatinases-targeting scFv-based Fusion Protein Shows Enhanced Antitumour Activity with Endostar against Hepatoma., PMID:25615234
Investigating the role of angiogenesis in systemic lupus erythematosus., PMID:25359881
Involvement of the NF-кB/p50/Bcl-3 complex in response to antiangiogenic therapy in a mouse model of metastatic renal cell carcinoma., PMID:25113400
Pre-clinical toxicokinetics and safety study of M2ES, a PEGylated recombinant human endostatin, in rhesus monkeys., PMID:24878240
Superficial dermal fibroblasts enhance basement membrane and epidermal barrier formation in tissue-engineered skin: implications for treatment of skin basement membrane disorders., PMID:24004160
For research use only. Not for human or drug use.
