Catalog No.
PHH26901
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human PKN1 (Ser608-Gln871).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Protein kinase C-like PKN, Serine/threonine-protein kinase N1, PRK1, Serine-threonine protein kinase N, PKN, Protease-activated kinase 1, PRKCL1, PKN1, Protein-kinase C-related kinase 1, PAK-1, Protein kinase PKN-alpha, PAK1, Protein kinase C-like 1
Purification
Purified by antigen affinity column.
Accession
Q16512
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
PKN1 kinase-negative knock-in mice develop splenomegaly and leukopenia at advanced age without obvious autoimmune-like phenotypes., PMID:31562379
Cardiolipin activates antigen-presenting cells via TLR2-PI3K-PKN1-AKT/p38-NF-kB signaling to prime antigen-specific naïve T cells in mice., PMID:29313959
The protein kinase C super-family member PKN is regulated by mTOR and influences differentiation during prostate cancer progression., PMID:28875501
Co-immunoprecipitation of Plant Receptor Kinases., PMID:28567647
Seroprevalence of antibodies against Pkn1, a novel potential immunogen, in Chlamydia trachomatis-infected Macaca nemestrina and human patients., PMID:25032212
Protein kinases paralleling late-phase LTP formation in dorsal hippocampus in the rat., PMID:24911953
Protein kinase N1, a cell inhibitor of Akt kinase, has a central role in quality control of germinal center formation., PMID:23223530
The interaction of PKN3 with RhoC promotes malignant growth., PMID:22217540
Infectivity of Leishmania mexicana is associated with differential expression of protein kinase C-like triggered during a cell-cell contact., PMID:19851504
Protein kinase C-related kinase 2 regulates hepatitis C virus RNA polymerase function by phosphorylation., PMID:15364941
Generation of a constitutively active fragment of PKN in microglia/macrophages after middle cerebral artery occlusion in rats., PMID:11723183
Phosphorylation of tau is regulated by PKN., PMID:11104762
Phosphorylation of CPI-17, an inhibitor of myosin phosphatase, by protein kinase N., PMID:10924361
Induction of a 55-kDa PKN cleavage product by ischemia/reperfusion model in the rat retina., PMID:10634597
PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2., PMID:10226025
A protein kinase, PKN, accumulates in Alzheimer neurofibrillary tangles and associated endoplasmic reticulum-derived vesicles and phosphorylates tau protein., PMID:9736660
PKN interacts with a paraneoplastic cerebellar degeneration-associated antigen, which is a potential transcription factor., PMID:9637778
PRK1 is targeted to endosomes by the small GTPase, RhoB., PMID:9478917
Leukocyte function-associated antigen 1-dependent adhesion of rat hepatoma AH66F cells and inhibition by protein kinase C inhibitors., PMID:9214694
Translocation of PKN from the cytosol to the nucleus induced by stresses., PMID:8816775
Monoclonal antibodies against nuclear casein kinase NII (PK-N2)., PMID:2076898
For research use only. Not for human or drug use.
