Catalog No.
PHF64101
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CD156a/ADAM8 (Arg200-Arg390).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Disintegrin and metalloproteinase domain-containing protein 8, ADAM8, CD156a, MS2, Cell surface antigen MS2, ADAM 8
Purification
Purified by antigen affinity column.
Accession
P78325
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
ADAM 8 as a novel target for doxorubicin delivery to TNBC cells using magnetic thermosensitive liposomes., PMID:33338603
ADAM8 localizes to extravillous trophoblasts within the maternal-fetal interface and potentiates trophoblast cell line migration through a β1 integrin-mediated mechanism., PMID:30124911
ADAM8 expression in breast cancer derived brain metastases: Functional implications on MMP-9 expression and transendothelial migration in breast cancer cells., PMID:28986926
Haemorrhagic snake venom metalloproteases and human ADAMs cleave LRP5/6, which disrupts cell-cell adhesions in vitro and induces haemorrhage in vivo., PMID:28425175
IL-5-stimulated eosinophils adherent to periostin undergo stereotypic morphological changes and ADAM8-dependent migration., PMID:28378503
Inducible expression of A Disintegrin and Metalloproteinase 8 in chronic periodontitis and gingival epithelial cells., PMID:27859260
miR-720 is a downstream target of an ADAM8-induced ERK signaling cascade that promotes the migratory and invasive phenotype of triple-negative breast cancer cells., PMID:27039296
The metalloprotease-disintegrin ADAM8 contributes to temozolomide chemoresistance and enhanced invasiveness of human glioblastoma cells., PMID:25825051
Fibronectin fragments and the cleaving enzyme ADAM-8 in the degenerative human intervertebral disc., PMID:25010013
ADAM8 expression in invasive breast cancer promotes tumor dissemination and metastasis., PMID:24375628
Adam8 limits the development of allergic airway inflammation in mice., PMID:23670189
CD155 on human vascular endothelial cells attenuates the acquisition of effector functions in CD8 T cells., PMID:21330602
ADAM-8 isolated from human osteoarthritic chondrocytes cleaves fibronectin at Ala(271)., PMID:19714641
Human parainfluenza virus type 2 (HPIV2) induced host ADAM8 expression in human salivary adenocarcinoma cell line (HSY) during cell fusion., PMID:19284887
Expression and regulation of the metalloproteinase ADAM-8 during human neutrophil pathophysiological activation and its catalytic activity on L-selectin shedding., PMID:17548643
Reactivity of new adhesion molecules on lymphocytes from patients with chronic graft versus host disease., PMID:12793201
For research use only. Not for human or drug use.
