Catalog No.
PHA61501
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human SIAH2 (Ser68-Pro324).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
RING-type E3 ubiquitin transferase SIAH2, SIAH2, hSiah2, Seven in absentia homolog 2, Siah-2, E3 ubiquitin-protein ligase SIAH2
Purification
Purified by antigen affinity column.
Accession
O43255
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Construction and validation of antibody dependent cell phagocytosis related risk model in breast cancer., PMID:40442365
PIWIL2 suppresses Siah2-mediated degradation of HDAC3 and facilitates CK2α-mediated HDAC3 phosphorylation., PMID:29555935
The expression and function of E3 ligase SIAH2 in acute T lymphoblastic leukemia., PMID:26859780
High-density lipoproteins augment hypoxia-induced angiogenesis via regulation of post-translational modulation of hypoxia-inducible factor 1α., PMID:24022405
SIAH-mediated ubiquitination and degradation of acetyl-transferases regulate the p53 response and protein acetylation., PMID:23044042
Siah regulation of Pard3A controls neuronal cell adhesion during germinal zone exit., PMID:21109632
Wnt5a secretion stimulated by the extracellular calcium-sensing receptor inhibits defective Wnt signaling in colon cancer cells., PMID:17463182
Generation and analysis of Siah2 mutant mice., PMID:14645526
Regulation of BOB.1/OBF.1 stability by SIAH., PMID:11483518
For research use only. Not for human or drug use.
