Catalog No.
PHG05301
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human GRIN1/NMDAR1 (Asp23-His371).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
N-methyl-D-aspartate receptor subunit NR1, GluN1, Glutamate [NMDA] receptor subunit zeta-1, Glutamate receptor ionotropic, NMDA 1, NMD-R1, GRIN1, NMDAR1
Purification
Purified by antigen affinity column.
Accession
Q05586
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Bridging the gap: insights into sensorimotor deficits in NMDA receptor antibody encephalitis., PMID:40026244
Molecular scalpels dissect new GluN1 hot spots in anti-NMDA receptor encephalitis., PMID:39752539
NMDAR1 autoantibodies as potential biomarkers for schizophrenia phenotyping., PMID:39300631
NLRP4E regulates actin cap formation through SRC and CDC42 during oocyte meiosis., PMID:38730334
Cellular prion protein in human plasma-derived extracellular vesicles promotes neurite outgrowth via the NMDA receptor-LRP1 receptor system., PMID:35090893
Longitudinal CSF Findings in Autoimmune Encephalitis-A Monocentric Cohort Study., PMID:33828556
Exploratory investigation on antibodies to GluN1 and cognitive dysfunction in patients with chronic autoimmune psychosis., PMID:33359543
Characteristics of internalization of NMDA-type GluRs with antibodies to GluN1 and GluN2B., PMID:33091764
Autoimmune encephalitis., PMID:31808454
An update on anti-NMDA receptor encephalitis for neurologists and psychiatrists: mechanisms and models., PMID:31326280
Anti-N-Methyl-D-Aspartate Receptor Encephalitis: A Challenging Diagnosis in the Emergency Department., PMID:31268960
Rapid onset of altered mental status with progressive autonomic instability and hypoventilation in a 2-year-old male., PMID:32134592
Uncoupling the widespread occurrence of anti-NMDAR1 autoantibodies from neuropsychiatric disease in a novel autoimmune model., PMID:29426955
Serum complement levels in anti-N-methyl-d-aspartate receptor encephalitis., PMID:29053906
[Therapy of Antibody-Associated Autoimmune Encephalitis]., PMID:27299787
Ethanol upregulates NMDA receptor subunit gene expression in human embryonic stem cell-derived cortical neurons., PMID:26266540
Semi-quantitative analyses of antibodies to N-methyl-d-aspartate type glutamate receptor subunits (GluN2B & GluN1) in the clinical course of Rasmussen syndrome., PMID:25986190
Absence of N-Methyl-D-Aspartate Receptor IgG Autoantibodies in Schizophrenia: The Importance of Cross-Validation Studies., PMID:25970159
Differential alterations of neocortical GluN receptor subunits in patients with mixed subcortical ischemic vascular dementia and Alzheimer's disease., PMID:25261450
[Autoimmune encephalitis as a cause of psychosis]., PMID:24730197
Pathological reorganization of NMDA receptors subunits and postsynaptic protein PSD-95 distribution in Alzheimer's disease., PMID:24156266
Stroke patients develop antibodies that react with components of N-methyl-D-aspartate receptor subunit 1 in proportion to lesion size., PMID:23723305
Pilot study of iPS-derived neural cells to examine biologic effects of alcohol on human neurons in vitro., PMID:22486492
Association of GRIN1 and GRIN2A-D with schizophrenia and genetic interaction with maternal herpes simplex virus-2 infection affecting disease risk., PMID:21919190
Breast cancer expresses functional NMDA receptors., PMID:19784770
Dynamic expression patterns of G protein-regulated inducer of neurite outgrowth 1 (GRIN1) and its colocalization with Galphao implicate significant roles of Galphao-GRIN1 signaling in nervous system., PMID:18729205
The clinical potential of antiepileptic gene therapy., PMID:15500405
For research use only. Not for human or drug use.
