Catalog No.
YMJ85301
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Ala127-Leu309
Predicted molecular weight
22.91 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9WU72
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
BAFF, ZTNF4, BLYS, Tumor necrosis factor ligand superfamily member 13B, Dendritic cell-derived TNF-like molecule, TALL-1, TNF- and APOL-related leukocyte expressed ligand 1, BLyS, B lymphocyte stimulator, TNFSF13B, CD257, TNFSF20, TALL1, B-cell-activating factor
The Role of Glomerular and Serum Expression of Lymphocyte Activating Factors BAFF and APRIL in Patient with Membranous and IgA Nephropathies., PMID:40472229
Telitacicept for lupus nephritis with BAFF and APRIL double positivity in children: a case report., PMID:40420262
FCRL1 and BAFF mRNA Expression as Novel Diagnostic and Prognostic Biomarkers in Diffuse Large B-Cell Lymphoma: Expression Signatures Predict R-CHOP Therapy Response and Survival., PMID:39941037
OPG and BAFF as predictive biomarkers of the severity of SARS-CoV-2 infection., PMID:39888266
Development and therapeutic assessment of bispecific nanobodies targeting B-cell activating factor and interleukin-17 for the neutralization of inflammatory mediators in autoimmune diseases., PMID:39870268
CCN1 promotes APRIL/BAFF signaling in esophageal squamous cell carcinoma but attenuates it in esophageal adenocarcinoma., PMID:39806221
Comparative Analysis of Serum BAFF and IL-17 Levels Pre- and Post-Antipsychotic Treatment for Acute Schizophrenia., PMID:39796241
Matched serum- and urine-derived biomarkers of interstitial cystitis/bladder pain syndrome., PMID:39739829
A first-in-human, randomized study of the safety, pharmacokinetics and pharmacodynamics of povetacicept, an enhanced dual BAFF/APRIL antagonist, in healthy adults., PMID:39494621
Venetoclax dose escalation rapidly activates a BAFF/BCL-2 survival axis in chronic lymphocytic leukemia., PMID:39471335
T cell immuno-phenotyping : a source of predictive biomarkers for autoimmune hepatitis relapse., PMID:39424872
B-Cell Maturation Antigen (BCMA) as a Biomarker and Potential Treatment Target in Systemic Lupus Erythematosus., PMID:39409173
BAFF overexpression in triple-negative breast cancer promotes tumor growth by inducing IL-10-secreting regulatory B cells that suppress anti-tumor T cell responses., PMID:39400783
APRIL/BAFF upregulation is associated with clonal B-cell expansion in Hunner-type interstitial cystitis., PMID:39360360
Serum BAFF level is associated with the presence and severity of coronary artery disease and acute myocardial infarction., PMID:39227771
Current status of BAFF targeting immunotherapy in B-cell neoplasm., PMID:39222149
Serum BAFF levels are associated with the prognosis of idiopathic membranous nephropathy., PMID:39143819
Serum levels of B-cell activating factor are associated with a reduced risk of chronic lymphocytic leukemia., PMID:39112445
Changes in peripheral blood IL-9, Th9, and BAFF levels in patients with allergic rhinitis and their clinical implications., PMID:39093090
B Cell-activating factor (BAFF): A promising trans-nosographic biomarker of inflammation and autoimmunity in bipolar disorder and schizophrenia., PMID:39047848
Proof-of-concept study evaluating humoral primary immunodeficiencies via CJ:KREC ratio and serum BAFF level., PMID:38906917
Bronchiectasis, lymphadenopathies related to BAFF overexpression and lymphoplasmacytic cystitis as adverse events associated with prolonged use of rituximab in systemic autoimmune rheumatic diseases., PMID:38849075
A comparative study of different antiviral treatment protocols in HCV related cryoglobulinemic vasculitis., PMID:38782988
Association of B-cell activating factor gene variants with serum anti-JCV antibody positivity in male patients with multiple sclerosis under natalizumab treatment: Implications for progressive multifocal leukoencephalopathy risk stratification., PMID:38761670
Past and present discovery of the BAFF/APRIL system - A bibliometric study from 1999 to 2023., PMID:38714287
Assessment of serum inflammatory parameters in RRMS and SPMS patients., PMID:38697017
Serum BAFF (B-cell activating factor) and APRIL (a proliferation-inducing ligand) levels in the first trimester may predict the future development of gestational diabetes mellitus., PMID:38653036
Immune cell composition and inflammatory profile of human peri-implantitis and periodontitis lesions., PMID:38616555
An IL-1β-driven neutrophil-stromal cell axis fosters a BAFF-rich protumor microenvironment in individuals with multiple myeloma., PMID:38600356
An unappreciated cell survival-independent role for BAFF initiating chronic lymphocytic leukemia., PMID:38469292
Implications of IFNγ SNP rs2069705 in primary Sjögren's syndrome: transcriptional activation and B cell infiltration., PMID:38406824
Correlation Between B-Cell Activating Factor of the Tumor Necrosis Factor Family Level in Serum and Immune Inflammation in Patients with Neuropsychiatric Systemic Lupus Erythematosus and its Clinical Value., PMID:38329469
Associations between TNFSF13B polymorphisms and primary Sjögren's syndrome susceptibility in primary Sjögren's syndrome patients: A meta-analysis., PMID:38156381
Mechanistic insight on the role of iRhom2-TNF-α-BAFF signaling pathway in various autoimmune disorders., PMID:38151421
Human gingival fibroblasts are a source of B cell-activating factor during periodontal inflammation., PMID:38088123
B-cell activating factor gene variants in multiple sclerosis: Possible associations with disease susceptibility among females., PMID:37995946
HOOK1 Inhibits the Progression of Renal Cell Carcinoma via TGF-β and TNFSF13B/VEGF-A Axis., PMID:37085921
Tissue-resident memory T cell maintenance during antigen persistence requires both cognate antigen and interleukin-15., PMID:37083450
The BAFF-APRIL System in Cancer., PMID:36980677
Dysregulation of Gene Expressions in Multiple Sclerosis: TNFSF13B and Other Candidate Genes., PMID:36722235
TNFSF13B rs9514828 gene polymorphism and soluble B cell activating factor levels: Association with apical periodontitis., PMID:36508294
Neutrophilic granulocyte-derived B-cell activating factor supports B cells in skin lesions in hidradenitis suppurativa., PMID:36481267
B cell-activating factor is involved in thrombocytopenia in patients with liver cirrhosis., PMID:36098792
Protein and functional isoform levels and genetic variants of the BAFF and APRIL pathway components in systemic lupus erythematosus., PMID:35780200
Correlation of Serum Levels of Interleukine-16, CCL27, Tumor Necrosis Factor-related Apoptosis-inducing Ligand, and B-cell Activating Factor with Multiple Sclerosis Severity., PMID:35524375
Serum Soluble B Cell-Activating Factor Is a Non-Invasive Biomarker of Antibody-Mediated Rejection in Kidney Allograft With Satisfactory Risk Stratification Performance But Negligible Diagnostic Value., PMID:35493478
B-cell activating factor (BAFF), BAFF promoter and BAFF receptor allelic variants in hepatitis C virus related Cryoglobulinemic Vasculitis and Non-Hodgkin's Lymphoma., PMID:35460540
Analysis of TNFSF13B polymorphisms and BAFF expression in rheumatoid arthritis and primary Sjögren's syndrome patients., PMID:35411715
Genetic Variants of the BAFF Gene and Risk of Fatigue Among Patients With Primary Sjögren's Syndrome., PMID:35371038
BAFF rs9514828 gene polymorphism and the risk of the development of inhibitors in children with severe haemophilia A., PMID:35316553