Catalog No.
YMN42401
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Glu65-Asp214
Predicted molecular weight
19.65 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9R0Q8
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
C-type lectin superfamily member 9, Macrophage-inducible C-type lectin, MINCLE, CLECSF9, CLEC4E, C-type lectin domain family 4 member E
Diagnostic biomarkers and immune infiltration profiles common to COVID-19, acute myocardial infarction and acute ischaemic stroke using bioinformatics methods and machine learning., PMID:40340571
Exploration of the shared gene signatures and molecular mechanisms between cardioembolic stroke and ischemic stroke., PMID:40264650
Phylogenetic and structural insights into the origin of C-type lectin Mincle in vertebrates., PMID:40119899
The miR-22-5p/Clec4e axis has diagnostic potential in fructose-induced nonalcoholic fatty liver disease., PMID:39978254
Microbiota translocation following intestinal barrier disruption promotes Mincle-mediated training of myeloid progenitors in the bone marrow., PMID:39848243
Study on Immune-Related Genes and Clinical Validation of Acute Myocardial Infarction Based on Bioinformatics., PMID:39820825
IL-33, a neutrophil extracellular trap-related gene involved in the progression of diabetic kidney disease., PMID:39797951
Hydrogel activation of Mincle receptors for tumor cell processing: A novel approach in cancer immunotherapy., PMID:39002516
Identification of core genes shared by ischemic stroke and myocardial infarction using an integrated approach., PMID:38968466
Revealing the Molecular Mechanism of Sageretia theezans in the Treatment of Hemorrhoids based on Network Pharmacology., PMID:38934275
Mincle receptor in macrophage and neutrophil contributes to the unresolved inflammation during the transition from acute kidney injury to chronic kidney disease., PMID:38770013
Heterogeneity of immune cells and their communications unveiled by transcriptome profiling in acute inflammatory lung injury., PMID:38745657
Protocol to identify the ligand binding site of Mincle using NMR spectroscopy., PMID:38573861
CLEC4E upregulation in gastric cancer: A potential therapeutic target correlating with tumor-associated macrophages., PMID:38463883
Punicalagin promotes mincle-mediated phagocytosis of macrophages via the NF-κB and MAPK signaling pathways., PMID:38428663
C-type lectin receptor expression is a hallmark of neutrophils infiltrating the skin in epidermolysis bullosa acquisita., PMID:37799716
Idiopathic Pulmonary Fibrosis Molecular Substrates Revealed by Competing Endogenous RNA Regulatory Networks., PMID:37540140
Structural basis for plastic glycolipid recognition of the C-type lectin Mincle., PMID:37348496
Psoriasis and Leprosy: An Arcane Relationship., PMID:37337513
Characterisation of the bovine C-type lectin receptor Mincle and potential evidence for an endogenous ligand., PMID:37275870
Non-invasive STEMI-related biomarkers based on meta-analysis and gene prioritization., PMID:37216774
Proteomic analysis of liver tissue reveals Aeromonas hydrophila infection mediated modulation of host metabolic pathways in Labeo rohita., PMID:36906258
Acute systemic myeloid inflammatory and stress response in severe food allergic reactions., PMID:36756745
FAM21 is critical for TLR2/CLEC4E-mediated dendritic cell function against Candida albicans., PMID:36717248
Astragalus polysaccharides protect against inactivated Vibrio alginolyticus-induced inflammatory injury in macrophages of large yellow croaker., PMID:36206995
Identification of key monocytes/macrophages related gene set of the early-stage abdominal aortic aneurysm by integrated bioinformatics analysis and experimental validation., PMID:36186997
C-type lectin Mincle-dependent and -independent activation of invariant NKT cells by exposure to Helicobacter pylori α-cholesteryl glucosides., PMID:35920835
Macrophage-inducible C-type lectin activates B cells to promote T cell reconstitution in heart allograft recipients., PMID:35294793
Pathogenic TNF-α drives peripheral nerve inflammation in an Aire-deficient model of autoimmunity., PMID:35058362
Single-cell RNA sequencing of mouse left ventricle reveals cellular diversity and intercommunication., PMID:34859688
Decoding the Transcriptional Response to Ischemic Stroke in Obese and Non-obese Mice Brain., PMID:34702150
Upregulation of a nuclear factor-kappa B-interacting immune gene network in mice cochleae with age-related hearing loss., PMID:34679122
Clec4e-Receptor Signaling in Myocardial Repair After Ischemia-Reperfusion Injury., PMID:34466750
A case-control study on correlation between the single nucleotide polymorphism of CLEC4E and the susceptibility to tuberculosis among Han people in Western China., PMID:34376176
Orientia tsutsugamushi selectively stimulates the C-type lectin receptor Mincle and type 1-skewed proinflammatory immune responses., PMID:34320039
Identification and characterization of a C-type lectin in turbot (Scophthalmus maximus) which functioning as a pattern recognition receptor that binds and agglutinates various bacteria., PMID:34062237
Macrophage cytokine responses to commensal Gram-positive Lactobacillus salivarius strains are TLR2-independent and Myd88-dependent., PMID:33723368
The early response expression profiles of miRNA-mRNA in farmed yellow catfish (Pelteobagrus fulvidraco) challenged with Edwardsiella tarda infection., PMID:33476668
Fibronectin-functionalization of 3D collagen networks supports immune tolerance and inflammation suppression in human monocyte-derived macrophages., PMID:33276199
SHP-1 Regulates Antigen Cross-Presentation and Is Exploited by Leishmania to Evade Immunity., PMID:33264612
Conjunctival transcriptome analysis reveals the overexpression of multiple pattern recognition receptors in vernal keratoconjunctivitis., PMID:33098984
Helicobacter pylori metabolites exacerbate gastritis through C-type lectin receptors., PMID:32991669
CLEC4E (Mincle) genetic variation associates with pulmonary tuberculosis in Guinea-Bissau (West Africa)., PMID:32971250
Immune-triggering effect of the foodborne parasite Kudoa septempunctata through the C-type lectin Mincle in HT29 cells., PMID:32843128
Zinc transporter SLC39A7 relieves zinc deficiency to suppress alternative macrophage activation and impairment of phagocytosis., PMID:32645059
Immune Recognition of Pathogen-Derived Glycolipids Through Mincle., PMID:32152942
Sensing Tissue Damage by Myeloid C-Type Lectin Receptors., PMID:31974758
Sighting acute myocardial infarction through platelet gene expression., PMID:31863085
C-type lectin receptors Mcl and Mincle control development of multiple sclerosis-like neuroinflammation., PMID:31725411
Induction of autophagy through CLEC4E in combination with TLR4: an innovative strategy to restrict the survival of Mycobacterium tuberculosis., PMID:31462144
For research use only. Not for human or drug use.
