Catalog No.
YMG02501
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Leu420-Ser653
Predicted molecular weight
27.83 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9R098
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
HGF activator, Hepatocyte growth factor activator, HGFA, HGFAC
Note
For research use only.
Hepatic gene expression and plasma albumin concentration related to outcome after attenuation of a congenital portosystemic shunt in dogs., PMID:21641243
Identification of hepatocyte growth factor activator (Hgfac) gene as a target of HNF1α in mouse β-cells., PMID:22877752
Trans-ethnic meta-analysis identifies common and rare variants associated with hepatocyte growth factor levels in the Multi-Ethnic Study of Atherosclerosis (MESA)., PMID:25998175
Differential expression of genes encoding proteins of the HGF/MET system in insulinomas., PMID:26435753
Aberrant methylation and silencing of the SPINT2 gene in high-grade gliomas., PMID:29987920
Hepatocyte Growth Factor Activator: A Proteinase Linking Tissue Injury with Repair., PMID:30388869
HGFAC expression decreased in liver cancer and its low expression correlated with DNA hypermethylation and poor prognosis., PMID:30635948
Proteome of normal human perilymph and perilymph from people with disabling vertigo., PMID:31185063
Comparative toxicoproteogenomics of mouse and rat liver identifies TCDD-resistance genes., PMID:31511937
Bioinformatics analysis of key biomarkers and potential molecular mechanisms in hepatocellular carcinoma induced by hepatitis B virus., PMID:32443377
TLR3 promotes hepatocyte proliferation after partial hepatectomy by stimulating uPA expression and the release of tissue-bound HGF., PMID:32539223
COVID-19-Related Coagulopathy-Is Transferrin a Missing Link?, PMID:32751741
Epistatic evidence for gender-dependant slow neurotransmission signalling in substance use disorders: PPP1R12B versus PPP1R1B., PMID:33096475
[Liver Tissue-specific Genes IGFALS,CYP3A4,SLC22A1 and CYP2E1 May be Associated with Poor Prognosis of Liver Cancer]., PMID:34238413
Role of ribosomal RNA released from red cells in blood coagulation in zebrafish and humans., PMID:34547768
Genome-wide identification of copy number variation and association with fat deposition in thin and fat-tailed sheep breeds., PMID:35614300
Back-translating GWAS findings to animal models reveals a role for Hgfac and Slc39a8 in alcohol and nicotine consumption., PMID:35661789
Alterations in the kallikrein-kinin system predict death after heart transplant., PMID:35986069
A top-down approach to uncover the hidden ligandome of low-density lipoprotein receptor-related protein 1 in cartilage., PMID:36028175
HGFAC is a ChREBP-regulated hepatokine that enhances glucose and lipid homeostasis., PMID:36413406
The effect of hepatocyte growth factor on intestinal adaption in an experimental model of short bowel syndrome., PMID:36631569
Therapeutic targets for inflammatory bowel disease: proteome-wide Mendelian randomization and colocalization analyses., PMID:36857861
Molecular mechanisms investigation for liver metastasis of colorectal cancer by combined bioinformatic gene expression profile analysis., PMID:36868002
Integrated analysis of the lncRNA-associated ceRNA network in Alzheimer's disease., PMID:37187245
Genetic vulnerability to Crohn's disease reveals a spatially resolved epithelial restitution program., PMID:37878672
Clinical characterization and proteomic profiling of lean nonalcoholic fatty liver disease., PMID:38034020
Integrating plasma proteomics with genome-wide association data to identify novel drug targets for inflammatory bowel disease., PMID:39009667
ADH4-a potential prognostic marker for hepatocellular carcinoma with possible immune-related implications., PMID:39090641
Identification of potential novel targets for treating inflammatory bowel disease using Mendelian randomization analysis., PMID:39414629
p53/HIF-1α regulates neuronal aging and autophagy in spinal cord ischemia/reperfusion injury., PMID:39515667
An exploratory SWATH plasma proteomics analysis of phyllodes tumor- a type of female breast tumor., PMID:39933222
Potential drug targets for ovarian cancer identified through Mendelian randomization and colocalization analysis., PMID:39972314
Combined Therapy Targeting MET and Pro-HGF Activation Shows Significant Therapeutic Effect Against Liver Metastasis of CRPC., PMID:40076928
Sex differences in proteomics of cardiovascular disease - Results from the Yale-CMD registry., PMID:40224648
Multi-omics analyses, cell experiments, and network pharmacology tools identified key proteins and candidate drugs for alopecia areata treatment., PMID:40442619
For research use only. Not for human or drug use.
