Catalog No.
YMA01401
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Ser17-Tyr157
Predicted molecular weight
44.22 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q3U497
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
IREM-3, CLM-7, Leukocyte mono-Ig-like receptor 5, CD300b, Immune receptor expressed on myeloid cells 3, CD300LB, CD300B, Triggering receptor expressed on myeloid cells 5, CMRF35-like molecule 7, LMIR5, CMRF35A2, IREM3, CD300 antigen-like family member B, CMRF35-A2, TREM-5, TREM5, CLM7
Peptidoglycan from Bacillus anthracis Inhibits Human Macrophage Efferocytosis in Part by Reducing Cell Surface Expression of MERTK and TIM-3., PMID:38517345
CD300a blockade enhances efferocytosis by infiltrating myeloid cells and ameliorates neuronal deficit after ischemic stroke., PMID:34652960
The phytosphingosine-CD300b interaction promotes zymosan-induced, nitric oxide-dependent neutrophil recruitment., PMID:30647146
Effect of Specific Mutations in Cd300 Complexes Formation; Potential Implication of Cd300f in Multiple Sclerosis., PMID:29051512
Pertussis toxin targets the innate immunity through DAP12, FcRγ, and MyD88 adaptor proteins., PMID:28089363
Lipopolysaccharide-Induced CD300b Receptor Binding to Toll-like Receptor 4 Alters Signaling to Drive Cytokine Responses that Enhance Septic Shock., PMID:27261276
The immunobiology of Campylobacter jejuni: Innate immunity and autoimmune diseases., PMID:26709064
Evidence for TLR4 and FcRγ-CARD9 activation by cholera toxin B subunit and its direct bindings to TREM2 and LMIR5 receptors., PMID:26021803
3-O-sulfo-β-D-galactose moiety of endogenous sulfoglycolipids is a potential ligand for immunoglobulin-like receptor LMIR5., PMID:25172093
Campylobacter jejuni targets immunoglobulin-like receptor LMIR5., PMID:25172092
CD300b regulates the phagocytosis of apoptotic cells via phosphatidylserine recognition., PMID:25034781
LMIR5 extracellular domain activates myeloid cells through toll-like receptor 4., PMID:25004110
CD300 molecule regulation of human dendritic cell functions., PMID:23072861
A soluble form of LMIR5/CD300b amplifies lipopolysaccharide-induced lethal inflammation in sepsis., PMID:22772446
All-trans-retinoic acid and Erk1/2 signaling synergistically regulate the expression of CD300B in human monocytic cells., PMID:21450279
CD300 heterocomplexes, a new and family-restricted mechanism for myeloid cell signaling regulation., PMID:20959446
TIM1 is an endogenous ligand for LMIR5/CD300b: LMIR5 deficiency ameliorates mouse kidney ischemia/reperfusion injury., PMID:20566714
Molecular and functional characterization of CD300b, a new activating immunoglobulin receptor able to transduce signals through two different pathways., PMID:16920917
For research use only. Not for human or drug use.
