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Anti-DUSP6 Polyclonal Antibody

Catalog #:   PHH38301 Specific References (22) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q16828
Overview

Catalog No.

PHH38301

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human DUSP6 (Met1-Leu347).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Mitogen-activated protein kinase phosphatase 3,MKP3,DUSP6,PYST1,MAP kinase phosphatase 3,Dual specificity protein phosphatase PYST1,Dual specificity protein phosphatase 6,MKP-3

Purification

Purified by antigen affinity column.

Accession

Q16828

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • WESTERN BLOT
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with DUSP6 antibody (PHH38301) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 41 kDa
    Observed MW: 41 kDa
References

Combined KRAS-MAPK pathway inhibitors and HER2-directed drug conjugate is efficacious in pancreatic cancer., PMID:38509064

Combination of an Autoantibody Panel and Alpha-Fetoprotein for Early Detection of Hepatitis B Virus-Associated Hepatocellular Carcinoma., PMID:38489403

A novel immunodiagnosis panel for hepatocellular carcinoma based on bioinformatics and the autoantibody-antigen system., PMID:34821436

The integrin αvβ6 drives pancreatic cancer through diverse mechanisms and represents an effective target for therapy., PMID:31259422

Nuclear-Biased DUSP6 Expression is Associated with Cancer Spreading Including Brain Metastasis in Triple-Negative Breast Cancer., PMID:31238530

p38-MAP Kinase Negatively Regulates the Slow Force Response to Stretch in Rat Myocardium through the Up-Regulation of Dual Specificity Phosphatase 6 (DUSP6)., PMID:30816666

DUSP6 mediates T cell receptor-engaged glycolysis and restrains TFH cell differentiation., PMID:30087184

Effect of FGF2 on the activity of SPRYs/DUSP6/ERK signaling pathway in endometrial glandular epithelial cells of endometriosis., PMID:29630097

Characterization of MK-4166, a Clinical Agonistic Antibody That Targets Human GITR and Inhibits the Generation and Suppressive Effects of T Regulatory Cells., PMID:28611044

Identification of Pharmacodynamic Transcript Biomarkers in Response to FGFR Inhibition by AZD4547., PMID:27550940

CAPE suppresses migration and invasion of prostate cancer cells via activation of non-canonical Wnt signaling., PMID:27191743

Overcoming cetuximab resistance in HNSCC: the role of AURKB and DUSP proteins., PMID:25192874

Novel pathways in the pathobiology of human abdominal aortic aneurysms., PMID:22797469

Phosphorylation of the kinase interaction motif in mitogen-activated protein (MAP) kinase phosphatase-4 mediates cross-talk between protein kinase A and MAP kinase signaling pathways., PMID:21908610

Stem cell property epithelial-to-mesenchymal transition is a core transcriptional network for predicting cetuximab (Erbitux™) efficacy in KRAS wild-type tumor cells., PMID:21104905

Administration of betaHCG leads to dose-dependent changes of gene expression signature of endometriotic stromal cells., PMID:20395176

Identification of protein tyrosine phosphatases and dual-specificity phosphatases in mammalian spermatozoa and their role in sperm motility and protein tyrosine phosphorylation., PMID:19211810

Changes in gene expression induced by tienilic Acid and sulfamethoxazole: testing the danger hypothesis., PMID:18958736

Differential gene expression analysis reveals generation of an autocrine loop by a mutant epidermal growth factor receptor in glioma cells., PMID:16424019

Cell-active dual specificity phosphatase inhibitors identified by high-content screening., PMID:12954332

MAP kinase phosphatase-1 is induced in abnormal fibers in inclusion body myositis., PMID:12913191

Isolation of the human genes encoding the pyst1 and Pyst2 phosphatases: characterisation of Pyst2 as a cytosolic dual-specificity MAP kinase phosphatase and its catalytic activation by both MAP and SAP kinases., PMID:9788880

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-DUSP6 Polyclonal Antibody [PHH38301]
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