Catalog No.
PHH38301
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human DUSP6 (Met1-Leu347).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Mitogen-activated protein kinase phosphatase 3,MKP3,DUSP6,PYST1,MAP kinase phosphatase 3,Dual specificity protein phosphatase PYST1,Dual specificity protein phosphatase 6,MKP-3
Purification
Purified by antigen affinity column.
Accession
Q16828
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Combined KRAS-MAPK pathway inhibitors and HER2-directed drug conjugate is efficacious in pancreatic cancer., PMID:38509064
Combination of an Autoantibody Panel and Alpha-Fetoprotein for Early Detection of Hepatitis B Virus-Associated Hepatocellular Carcinoma., PMID:38489403
A novel immunodiagnosis panel for hepatocellular carcinoma based on bioinformatics and the autoantibody-antigen system., PMID:34821436
The integrin αvβ6 drives pancreatic cancer through diverse mechanisms and represents an effective target for therapy., PMID:31259422
Nuclear-Biased DUSP6 Expression is Associated with Cancer Spreading Including Brain Metastasis in Triple-Negative Breast Cancer., PMID:31238530
p38-MAP Kinase Negatively Regulates the Slow Force Response to Stretch in Rat Myocardium through the Up-Regulation of Dual Specificity Phosphatase 6 (DUSP6)., PMID:30816666
DUSP6 mediates T cell receptor-engaged glycolysis and restrains TFH cell differentiation., PMID:30087184
Effect of FGF2 on the activity of SPRYs/DUSP6/ERK signaling pathway in endometrial glandular epithelial cells of endometriosis., PMID:29630097
Characterization of MK-4166, a Clinical Agonistic Antibody That Targets Human GITR and Inhibits the Generation and Suppressive Effects of T Regulatory Cells., PMID:28611044
Identification of Pharmacodynamic Transcript Biomarkers in Response to FGFR Inhibition by AZD4547., PMID:27550940
CAPE suppresses migration and invasion of prostate cancer cells via activation of non-canonical Wnt signaling., PMID:27191743
Overcoming cetuximab resistance in HNSCC: the role of AURKB and DUSP proteins., PMID:25192874
Novel pathways in the pathobiology of human abdominal aortic aneurysms., PMID:22797469
Phosphorylation of the kinase interaction motif in mitogen-activated protein (MAP) kinase phosphatase-4 mediates cross-talk between protein kinase A and MAP kinase signaling pathways., PMID:21908610
Stem cell property epithelial-to-mesenchymal transition is a core transcriptional network for predicting cetuximab (Erbitux™) efficacy in KRAS wild-type tumor cells., PMID:21104905
Administration of betaHCG leads to dose-dependent changes of gene expression signature of endometriotic stromal cells., PMID:20395176
Identification of protein tyrosine phosphatases and dual-specificity phosphatases in mammalian spermatozoa and their role in sperm motility and protein tyrosine phosphorylation., PMID:19211810
Changes in gene expression induced by tienilic Acid and sulfamethoxazole: testing the danger hypothesis., PMID:18958736
Differential gene expression analysis reveals generation of an autocrine loop by a mutant epidermal growth factor receptor in glioma cells., PMID:16424019
Cell-active dual specificity phosphatase inhibitors identified by high-content screening., PMID:12954332
MAP kinase phosphatase-1 is induced in abnormal fibers in inclusion body myositis., PMID:12913191
Isolation of the human genes encoding the pyst1 and Pyst2 phosphatases: characterisation of Pyst2 as a cytosolic dual-specificity MAP kinase phosphatase and its catalytic activation by both MAP and SAP kinases., PMID:9788880
For research use only. Not for human or drug use.
