Catalog No.
YHN34101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met523-Thr710
Predicted molecular weight
23.87 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9NVR2
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
C8orf35, Int10, INTS10, Integrator complex subunit 10
Note
For research use only.
[Screening PIAS2-interacting proteins in the mouse using the yeast two-hybrid system]., PMID:21961235
Identification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemia., PMID:22076464
Bioinformatics analysis of gene expression profiles in childhood B-precursor acute lymphoblastic leukemia., PMID:25431969
Genome-wide association study of nicotine dependence in American populations: identification of novel risk loci in both African-Americans and European-Americans., PMID:25555482
Genome-wide association study identifies 8p21.3 associated with persistent hepatitis B virus infection among Chinese., PMID:27244555
Somatic Mutation Patterns in Hemizygous Genomic Regions Unveil Purifying Selection during Tumor Evolution., PMID:28027311
Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium., PMID:28430825
INTS10-INTS13-INTS14 form a functional module of Integrator that binds nucleic acids and the cleavage module., PMID:32647223
Structure of the catalytic core of the Integrator complex., PMID:33548203
Effects of genetic polymorphisms in INTS10 and their interaction with environmental factors on progression from persistent HBV infection to hepatocellular carcinoma., PMID:34133796
A Novel Prognostic Model for Oral Squamous Cell Carcinoma: The Functions and Prognostic Values of RNA-Binding Proteins., PMID:34395233
Mutations in the non-coding RNU4ATAC gene affect the homeostasis and function of the Integrator complex., PMID:36537210
Structural basis of Integrator-dependent RNA polymerase II termination., PMID:38570683
Structural basis of the Integrator complex assembly and association with transcription factors., PMID:38823386
The enhancer module of Integrator controls cell identity and early neural fate commitment., PMID:39592860
For research use only. Not for human or drug use.
