Catalog No.
YMD72101
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Phe90-Val232
Predicted molecular weight
19 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O54709
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NKG2-D type II integral membrane protein, Killer cell lectin-like receptor subfamily K member 1, NK cell receptor D, NKG2-D-activating NK receptor, CD314, Klrk1, Nkg2d
Harnessing NKG2D CAR-T cells with radiotherapy: a novel approach for esophageal squamous cell carcinoma treatment., PMID:40510363
Two major human phenotypes of MICA molecules and their differential activation to NK cells via NKG2D receptor., PMID:40458406
Effects of functional antioxidants on the expansion of gamma delta T-cells and their cellular cytotoxicity against bladder cancer cells., PMID:40452041
Curcumin combined with arsenic trioxide enhances autophagy and immune surveillance to inhibit immune escape in acute myeloid leukemia., PMID:40440957
Distinct immunity dynamics of natural killer cells in mild and moderate COVID-19 cases during the Omicron variant phase., PMID:40421029
NKG2D triggering hampers DNAM-1-mediated signaling in human NK cells., PMID:40421025
Tandem CAR T-cells targeting CD19 and NKG2DL can overcome CD19 antigen escape in B-ALL., PMID:40416955
N6-methyladenosine RNA base modification regulates NKG2D-dependent and cytotoxic genes expression in natural killer cells., PMID:40389988
Macrophage-derived pro-inflammatory cytokines augment the cytotoxicity of cytokine-induced killer cells by strengthening the NKG2D pathway in multiple myeloma., PMID:40369131
Epigenetic silencing of DNA sensing pathway by FOXM1 blocks stress ligand-dependent antitumor immunity and immune memory., PMID:40295473
Heterogeneity of γδ T-cell subsets and their clinical correlation in patients with AML., PMID:40236710
23ME-01473, an Fc Effector-Enhanced Anti-ULBP6/2/5 Antibody, Restores NK Cell-Mediated Antitumor Immunity through NKG2D and FcγRIIIa Activation., PMID:40116579
Overexpression of NKG2D and IL24 in NK Cell-Derived Exosomes for Cancer Therapy., PMID:40076725
Impaired immune reconstitution in HIV infection: the role of CD4+ T-cell-associated NKG2D ligands, CD4+ T-cell subsets imbalance, and immune function deficiency., PMID:40061947
Frizzled-7-targeting antibody-derived bifunctional protein retargets NK cells against triple-negative breast cancer cells via MICA-NKG2D axis., PMID:40021214
Diethyldithiocarbamate-copper complex ignites the tumor microenvironment through NKG2D-NKG2DL axis., PMID:40013140
HCMV Variants Expressing ULBP2 Enhance the Function of Human NK Cells via its Receptor NKG2D., PMID:39931744
Sodium valproate enhances efficacy of NKG2D CAR-T cells against glioblastoma., PMID:39877353
Amphiphilic Polyaspartamide Derivatives with Cholesterol Introduction Enhanced Ex Vivo mRNA Transfection Efficiency to Natural Killer Cells., PMID:39847497
Entry into the lytic cycle exposes EBV-infected cells to NK cell killing via upregulation of the MICB ligand for NKG2D and activation of the CD56bright and NKG2A+KIR+CD56dim subsets., PMID:39676862
Blocking CXCR3B Expression Increases Tumor Aggressiveness in Hepatocellular Carcinoma., PMID:39626933
Agonistic anti-NKG2D antibody structure reveals unique stoichiometry and epitope compared to natural ligands., PMID:39582357
MICA and NKG2D gene polymorphisms influence graft survival, and response to therapy in kidney transplantation., PMID:39575256
Solid tumor immunotherapy using NKG2D-based adaptor CAR T cells., PMID:39566469
LIN28 upregulation in primary human T cells impaired CAR T antitumoral activity., PMID:39478867
Thermosensitive hyaluronic acid-manganese-capsaicin complex nanogel improving NKG2D/CAR-T melanoma treatment through adjusting tumor microenvironment., PMID:39389490
An altered natural killer cell immunophenotype characterizes clinically severe pediatric RSV infection., PMID:39383246
MHC class I polypeptide-related sequence B shedding modulates pancreatic tumor immunity via the activation of NKG2DLow T cells., PMID:39379424
Targeted therapy of multiple myeloma by IL21-NKG2D CAR-T cells., PMID:39373147
MAIT Cells in the Bone Marrow of Patients with Aplastic Anemia., PMID:39337644
Soluble MICA concentrations and genetic variability of MICA and its NKG2D receptor as factors affecting Graft-versus-Host Disease development after allogeneic haematopoietic stem cell transplantation., PMID:39332041
Peripheral NK cell phenotypic alteration and dysfunctional state post hepatitis B subviral particles stimulation in CHB patients: evading immune surveillance., PMID:39328404
NKG2D (Natural Killer Group 2, Member D) ligand expression and ameloblastoma recurrence: a retrospective immunohistological pilot study., PMID:39289711
Bispecific killer cell engagers employing species cross-reactive NKG2D binders redirect human and murine lymphocytes to ErbB2/HER2-positive malignancies., PMID:39267747
A potential mechanism of tumor immune escape: Regulation and application of soluble natural killer group 2 member D ligands (Review)., PMID:39155864
Expression and function of the major histocompatibility complex (MHC) class I chain-related A (MICA)*010 in NK cell killing activity., PMID:39116667
NKG2D-bispecific enhances NK and CD8+ T cell antitumor immunity., PMID:39112670
A human autoimmune organoid model reveals IL-7 function in coeliac disease., PMID:39048815
CircARAP2 controls sMICA-induced NK cell desensitization by erasing CTCF/PRC2-induced suppression in early endosome marker RAB5A., PMID:39048814
A novel NKp80-based strategy for universal identification of normal, reactive and tumor/clonal natural killer-cells in blood., PMID:39040115
Regulation of the PD-1/PD-L1 Axis and NK Cell Dysfunction by Exosomal miR-552-5p in Gastric Cancer., PMID:39020183
Endometriotic Tissue-derived Exosomes Downregulate NKG2D-mediated Cytotoxicity and Promote Apoptosis: Mechanisms for Survival of Ectopic Endometrial Tissue in Endometriosis., PMID:38984872
The HHV-6B U20 glycoprotein binds ULBP1, masking it from recognition by NKG2D and interfering with natural killer cell activation., PMID:38953028
Cataloging circulating CD3+CD56+ NKT-like cells through a series of stimulating (NKG2D and DNAM-1) and inhibitory (PD-1, TIGIT, and Tim-3) immune checkpoint receptors in women diagnosed with precancerous cervical lesions or invasive cervical carcinoma., PMID:38945372
BCG priming followed by a novel interleukin combination activates Natural Killer cells to selectively proliferate and become anti-tumour long-lived effectors., PMID:38849432
Exosomal transfer of HCC-derived miR-17-5p downregulates NK cell function by targeting RUNX1-NKG2D axis., PMID:38820961
Immune signature and therapeutic approach of natural killer cell in chronic liver disease and hepatocellular carcinoma., PMID:38800890
Hydrophobic core evolution of major histocompatibility complex class I chain-related protein A for dramatic enhancing binding affinity., PMID:38788878
Memory-like differentiation enhances NK cell responses against colorectal cancer., PMID:38737793
The presence of cytotoxic CD4 and exhausted-like CD8+ T-cells is a signature of active tuberculosis., PMID:38734321
For research use only. Not for human or drug use.
