Catalog No.
PHH16101
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human TPSAB1/Tryptase-1 (Ile31-Pro275).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
TPSB1,TPS2,Tryptase I,Tryptase-1,TPSAB1,Tryptase alpha-1,Tryptase alpha/beta-1,TPS1
Purification
Purified by antigen affinity column.
Accession
Q15661
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Hereditary alpha-tryptasemia - a potential cause of severe anaphylactic reactions and a modifier of mast cell diseases., PMID:40450750
Elevated MS4A2 and IgE interaction in nasal polyps contributing to poor postoperative prognosis in patients with eosinophilic chronic rhinosinusitis., PMID:39828458
Elevated circulating group-2 innate lymphoid cells expressing activation markers and correlated tryptase AB1 levels in active ascariasis., PMID:39524451
Rapid identification of primary atopic disorders (PAD) by a clinical landmark-guided, upfront use of genomic sequencing., PMID:39381601
Idiopathic anaphylaxis: Diagnosis and management., PMID:34871155
Adult allergic rhinitis sufferers have unique nasal mucosal and peripheral blood immune gene expression profiles: A case-control study., PMID:34637606
Small intestinal immunopathology and GI-associated antibody formation in hereditary alpha-tryptasemia., PMID:33865872
Hereditary alpha-tryptasemia in 101 patients with mast cell activation-related symptomatology including anaphylaxis., PMID:33465452
Clinical response to omalizumab in patients with hereditary α-tryptasemia., PMID:31605754
Hereditary Alpha Tryptasemia: Genotyping and Associated Clinical Features., PMID:30007465
Oral sensitization to whey proteins induces age- and sex-dependent behavioral abnormality and neuroinflammatory responses in a mouse model of food allergy: a potential role of mast cells., PMID:29685134
Mast cell restricted mouse and human tryptase·heparin complexes hinder thrombin-induced coagulation of plasma and the generation of fibrin by proteolytically destroying fibrinogen., PMID:22235124
Allergen cleavage by effector cell-derived proteases regulates allergic inflammation., PMID:16585063
The B12 anti-tryptase monoclonal antibody disrupts the tetrameric structure of heparin-stabilized beta-tryptase to form monomers that are inactive at neutral pH and active at acidic pH., PMID:16493076
Potent pruritogenic action of tryptase mediated by PAR-2 receptor and its involvement in anti-pruritic effect of nafamostat mesilate in mice., PMID:16359660
Loss of histochemical identity in mast cells lacking carboxypeptidase A., PMID:15988029
Immunohistochemical evaluation of mast cells and mark activity tryptase and chymase in experimental fibrosarcoma., PMID:15638376
Gastric mucosal mast cells are increased in Helicobacter pylori-negative functional dyspepsia., PMID:15017654
An antibody raised against in vitro-derived human mast cells identifies mature mast cells and a population of cells that are Fc epsilon RI(+), tryptase(-), and chymase(-) in a variety of human tissues., PMID:12704212
Mast cells and macrophages in normal C57/BL/6 mice., PMID:12122446
Temporal distribution of distinct mast cell phenotypes during intestinal schistosomiasis in mice., PMID:12060316
Preliminary evaluation of mast cells and angiogenesis processes in experimental fibrosarcoma., PMID:12056643
Preliminary evaluation of mast cells in rats with an experimental fibrosarcoma induced by 3-methylcholanthrene., PMID:11820645
Mast cells express functional CD30 ligand and are the predominant CD30L-positive cells in Hodgkin's disease., PMID:11552987
IL-6 attenuates apoptosis, while neither IL-6 nor IL-10 affect the numbers or protease phenotype of fetal liver-derived human mast cells., PMID:11467999
[Other forms of immunomodulation in allergic patients]., PMID:10867378
Mast cell tryptase from pig lungs triggers infection by pneumotropic Sendai and influenza A viruses. Purification and characterization., PMID:10824103
Mast cell tryptase stimulates human lung fibroblast proliferation via protease-activated receptor-2., PMID:10645907
Detection of tryptase in bovine mast cells: comparison of enzyme- and immuno-histochemistry., PMID:10213671
Mitochondria-dependent and -independent regulation of Granzyme B-induced apoptosis., PMID:9874570
Involvement of alpha-4 integrins in allergic airway responses and mast cell degranulation in vivo., PMID:9769271
Immunolocalization of bFGF in pterygia: association with mast cells., PMID:9294687
Mast cell tryptase regulates rat colonic myocytes through proteinase-activated receptor 2., PMID:9294103
Molecular basis of proteolytic activation of Sendai virus infection and the defensive compounds for infection., PMID:9165079
[Tryptase: a diagnostic marker in allergic diseases]., PMID:8963645
Mast cells in loosening of totally replaced hips., PMID:8542692
The alpha form of human tryptase is the predominant type present in blood at baseline in normal subjects and is elevated in those with systemic mastocytosis., PMID:8675637
Proteinases of rat mast cells. Peritoneal but not intestinal mucosal mast cells express mast cell proteinase 5 and carboxypeptidase A., PMID:7594601
Expression of the c-kit gene product in normal and neoplastic mast cells but not in neoplastic basophil/mast cell precursors from chronic myelogenous leukaemia., PMID:7490680
Serine proteinases are regionally segregated within mast cell granules., PMID:7837788
Processing of procarboxypeptidase A and other zymogens in murine mast cells., PMID:7929294
Lack of expression of the tryptase mouse mast cell protease 7 in mast cells of the C57BL/6J mouse., PMID:8077672
Development of a new, more sensitive immunoassay for human tryptase: use in systemic anaphylaxis., PMID:7929694
Identification of targeting proteinase for rat alpha 1-macroglobulin in vivo. Mast-cell tryptase is a major component of the alpha 1-macroglobulin-proteinase complex endocytosed into rat liver lysosomes., PMID:7510477
Localization of rat tryptase to a subset of the connective tissue type of mast cell., PMID:7685789
For research use only. Not for human or drug use.
