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Anti-TRADD Polyclonal Antibody

Catalog #:   PHH14501 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q15628
Overview

Catalog No.

PHH14501

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human TRADD (Met61-Leu297).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

TRADD,TNFR1-associated DEATH domain protein,Tumor necrosis factor receptor type 1-associated DEATH domain protein,TNFRSF1A-associated via death domain

Purification

Purified by antigen affinity column.

Accession

Q15628

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • WESTERN BLOT
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with TRADD antibody (PHH14501) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 29 kDa
    Observed MW: 29 kDa
References

PeiTuQingXin formula alleviated atopic dermatitis symptoms via inhibiting TRADD/TRAF2/RIP1 complex mediated NF-κB signaling pathway activation., PMID:40056166

Effects of Aeromonas infection on the immune system, physical barriers and microflora structure in the intestine of juvenile grass carp (Ctenopharyngodon idella)., PMID:39059563

Molecular signatures in prion disease: altered death receptor pathways in a mouse model., PMID:38802941

Potential Molecular Mechanisms of Rare Anti-Tumor Immune Response by SARS-CoV-2 in Isolated Cases of Lymphomas., PMID:34696358

SNHG9, delivered by adipocyte-derived exosomes, alleviates inflammation and apoptosis of endothelial cells through suppressing TRADD expression., PMID:32007500

Downregulation of TNF-α/TNF-R1 Signals by AT-Lipoxin A4 May Be a Significant Mechanism of Attenuation in SAP-Associated Lung Injury., PMID:31097921

The small molecule NSM00191 specifically represses the TNF-α/NF-кB axis in foot and ankle rheumatoid arthritis., PMID:30416388

Increased expression of microRNA-338-3p contributes to production of Dsg3 antibody in pemphigus vulgaris patients., PMID:29749496

A novel synthetic analogue of ω-3 17,18-epoxyeicosatetraenoic acid activates TNF receptor-1/ASK1/JNK signaling to promote apoptosis in human breast cancer cells., PMID:28798154

MutY DNA Glycosylase Protects Cells From Tumor Necrosis Factor Alpha-Induced Necroptosis., PMID:28059467

TNF-α is involved in apoptosis triggered by grass carp reovirus infection in vitro., PMID:27346157

Evolutionarily conserved primary TNF sequences relate to its primitive functions in cell death induction., PMID:26729029

Renal microRNA- and RNA-profiles in progressive chronic kidney disease., PMID:26707063

GBM Derived Gangliosides Induce T Cell Apoptosis through Activation of the Caspase Cascade Involving Both the Extrinsic and the Intrinsic Pathway., PMID:26226135

Loss of tumor suppressive microRNA-31 enhances TRADD/NF-κB signaling in glioblastoma., PMID:26164206

Electrical conduction system apoptosis in type II diabetes mellitus., PMID:24398990

Agonist antibody activates death receptor 6 downstream signaling involving TRADD recruitment., PMID:24374337

Molecular profiling of acute and chronic rejections of renal allografts., PMID:24302958

Effect of infliximab combined with methylprednisolone on expressions of NF-κB, TRADD, and FADD in rat acute spinal cord injury., PMID:23574812

RIP1 expression is necessary for CD30-mediated cell death induction in anaplastic large-cell lymphoma cells., PMID:23545938

Ustekinumab improves psoriasis-related gene expression in noninvolved psoriatic skin without inhibition of the antimicrobial response., PMID:23278632

5-epi-Sinuleptolide induces cell cycle arrest and apoptosis through tumor necrosis factor/mitochondria-mediated caspase signaling pathway in human skin cancer cells., PMID:22348919

Critical role of the death receptor pathway in the antitumoral effects induced by hispanolone derivatives., PMID:22310289

TL1A and DR3, a TNF family ligand-receptor pair that promotes lymphocyte costimulation, mucosal hyperplasia, and autoimmune inflammation., PMID:22017439

Death signal transduction induced by co-immobilized TNF-α plus IFN-γ and the development of polymeric anti-cancer drugs., PMID:20832854

Altered expression of TNF-alpha signaling pathway proteins in systemic lupus erythematosus., PMID:20516030

Azadirachtin interacts with the tumor necrosis factor (TNF) binding domain of its receptors and inhibits TNF-induced biological responses., PMID:20018848

SYUNZ-16, a newly synthesized alkannin derivative, induces tumor cells apoptosis and suppresses tumor growth through inhibition of PKB/AKT kinase activity and blockade of AKT/FOXO signal pathway., PMID:19904742

Decrease in tumor necrosis factor-alpha receptor-associated death domain results from ubiquitin-dependent degradation in obstructive renal injury in rats., PMID:19541932

TRAIL receptor mediates inflammatory cytokine release in an NF-kappaB-dependent manner., PMID:19434100

Tumor necrosis factor alpha induces gamma-glutamyltransferase expression via nuclear factor-kappaB in cooperation with Sp1., PMID:18996094

Immunomagnetic isolation of tumor necrosis factor receptosomes., PMID:18662566

Zfra is an inhibitor of Bcl-2 expression and cytochrome c release from the mitochondria., PMID:18403180

Epidermal growth factor (EGF) activates nuclear factor-kappaB through IkappaBalpha kinase-independent but EGF receptor-kinase dependent tyrosine 42 phosphorylation of IkappaBalpha., PMID:17533369

Endotoxin preconditioning protects against the cytotoxic effects of TNFalpha after stroke: a novel role for TNFalpha in LPS-ischemic tolerance., PMID:17327883

Evidence that TNF-TNFR1-TRADD-TRAF2-RIP-TAK1-IKK pathway mediates constitutive NF-kappaB activation and proliferation in human head and neck squamous cell carcinoma., PMID:16953224

Evidence of tumor necrosis factor receptor 1 signaling in human temporal lobe epilepsy., PMID:16919273

Regulatory mechanisms and functions of intermediate filaments: a study using site- and phosphorylation state-specific antibodies., PMID:16542212

Expression of antiapoptotic and proapoptotic molecules in diabetic retinas., PMID:16424911

Analysis of gene and protein expression during monocyte-macrophage differentiation and cholesterol loading--cDNA and protein array study., PMID:15910854

Surface calreticulin mediates muramyl dipeptide-induced apoptosis in RK13 cells., PMID:15817475

Cloning and characterization of a small-size peptide Zfra that regulates the cytotoxic function of tumor necrosis factor by interacting with JNK1., PMID:15629131

[Signal transduction and biological characteristics of EB virus-encoded latent membrane protein 1 and its correlation with CD40]., PMID:15562778

Compartmentalization of TNF receptor 1 signaling: internalized TNF receptosomes as death signaling vesicles., PMID:15357952

An autocrine/paracrine loop linking keratin 14 aggregates to tumor necrosis factor alpha-mediated cytotoxicity in a keratinocyte model of epidermolysis bullosa simplex., PMID:14660619

TL1A-induced NF-kappaB activation and c-IAP2 production prevent DR3-mediated apoptosis in TF-1 cells., PMID:12882979

IL-12 plays a significant role in the apoptosis of human T cells in the absence of antigenic stimulation., PMID:12242079

Hepatitis C virus NS5A protein impairs TNF-mediated hepatic apoptosis, but not by an anti-FAS antibody, in transgenic mice., PMID:11886269

Treatment with the pure antiestrogen faslodex (ICI 182780) induces tumor necrosis factor receptor 1 (TNFR1) expression in MCF-7 breast cancer cells., PMID:11110059

The serine/threonine kinase HIPK2 interacts with TRADD, but not with CD95 or TNF-R1 in 293T cells., PMID:11032752

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-TRADD Polyclonal Antibody [PHH14501]
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