Catalog No.
EHB80802
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Met1-Gln179
Predicted molecular weight
22.56 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O95971
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CD160 antigen, Natural killer cell receptor BY55, CD160, CD160 antigen, soluble form, CD160, BY55
Targeting B and T lymphocyte attenuator in cancer immunotherapy., PMID:40480574
In vivo RNAi screen and validation reveals Ngp, Hba-a1, and S100a8 as novel inhibitory targets on T lymphocytes in liver cancer., PMID:40352930
Increased Herpesvirus Entry Mediator Expression on Circulating Monocytes and Subsets Predicts Poor Outcomes in Pancreatic Ductal Adenocarcinoma Patients., PMID:40243455
CLL cell-derived exosomes alter the immune and hematopoietic systems., PMID:40186065
Transcriptional signature of CD56bright NK cells predicts favourable prognosis in bladder cancer., PMID:39877370
Bioinformatics Analysis Reveals Microrchidia Family Genes as the Prognostic and Therapeutic Markers for Colorectal Cancer., PMID:39812044
Identification and Validation of Epithelial Cell Centre Regulatory Transcription Factors in the Gastric Cancer Microenvironment., PMID:39759895
Knockdown of RFC4 inhibits cell proliferation of oral squamous cell carcinoma in vitro and in vivo., PMID:39673181
Virus-specific Th17 Cells Are Induced by Human Cytomegalovirus after Renal Transplantation., PMID:39423238
The integrated molecular and histological analysis defines subtypes of esophageal squamous cell carcinoma., PMID:39419971
A study of the association of vitamin D receptor (VDR) as a predictive biomarker for immune checkpoint inhibitor therapy with immune invasion in colon adenocarcinoma., PMID:39378759
CD151 identifies an NK cell subset that is enriched in COVID-19 patients and correlates with disease severity., PMID:39374860
N-Glycan Branching Regulates BTLA Opposite to PD-1 to Limit T Cell Hyperactivity Induced by Branching Deficiency., PMID:39269653
Intratumoral CXCL13+ CD160+ CD8+ T cells promote the formation of tertiary lymphoid structures to enhance the efficacy of immunotherapy in advanced gastric cancer., PMID:39244216
Clinical Significance of TNFSF14/LIGHT and CD160 in Gastric Cancer and Peptic Ulcer Dyspepsia., PMID:39205564
Pan-cancer analysis of immune checkpoint receptors and ligands in various cells in the tumor immune microenvironment., PMID:39120585
Effect of HVEM/CD160 Variations on the Clear Cell Renal Carcinoma Risk and Overall Survival., PMID:38999968
Inhibition of interferon regulatory factor 4 orchestrates T cell dysfunction, extending mouse cardiac allograft survival., PMID:38811343
Diverse immunological dysregulation, chronic inflammation, and impaired erythropoiesis in long COVID patients with chronic fatigue syndrome., PMID:38797051
BET inhibition reforms the immune microenvironment and alleviates T cell dysfunction in chronic lymphocytic leukemia., PMID:38775157
Ex vivo sensitivity to broadly neutralizing antibodies and anti-CD4 antibody UB-421 of infectious viral isolates from people living with multidrug-resistant HIV., PMID:38728839
B-cell-directed CAR T-cell therapy activates CD8+ cytotoxic CARneg bystander T cells in patients and nonhuman primates., PMID:38558106
Identification of CD160-TM as a tumor target on triple negative breast cancers: possible therapeutic applications., PMID:38360636
Intraepithelial lymphocytes promote intestinal regeneration through CD160/HVEM signaling., PMID:38340986
Combination of oligo-fractionated irradiation with nivolumab can induce immune modulation in gastric cancer., PMID:38290769
Exhaustion of CD8+ T Cells in HBV Infection: Searching for Serological Markers., PMID:38182157
Evaluation of circulating plasma proteins in breast cancer using Mendelian randomisation., PMID:37996402
Biomarkers of Pathologic Complete Response to Neoadjuvant Immunotherapy in Mismatch Repair-Deficient Colorectal Cancer., PMID:37906636
Expression of HPV-16 E6 and E7 oncoproteins alters Chlamydia trachomatis developmental cycle and induces increased levels of immune regulatory molecules., PMID:37743859
Linking donor-specific antibody generation with natural killer cells in antibody-mediated kidney graft rejection., PMID:37739612
CD160 Signaling Is Essential for CD8+ T Cell Memory Formation via Upregulation of 4-1BB., PMID:37695685
Beyond the anti-PD-1/PD-L1 era: promising role of the BTLA/HVEM axis as a future target for cancer immunotherapy., PMID:37649037
TIM-3/Galectin-9 and CD160 expression in salivary adenoid cystic carcinoma., PMID:37455567
Screening of key genes related to ferroptosis and a molecular interaction network analysis in colorectal cancer using machine learning and bioinformatics., PMID:37435214
Anti-HVEM mAb therapy improves antitumoral immunity both in vitro and in vivo, in a novel transgenic mouse model expressing human HVEM and BTLA molecules challenged with HVEM expressing tumors., PMID:37230538
Interleukin-21 promotes Type-1 activation and cytotoxicity of CD56dimCD16bright natural killer cells during kidney allograft antibody-mediated rejection showing a new link between adaptive and innate humoral allo-immunity., PMID:37220805
Plasma extracellular vesicle transcriptomics identifies CD160 for predicting immunochemotherapy efficacy in lung cancer., PMID:37014183
Prognostic Value of EMT Gene Signature in Malignant Mesothelioma., PMID:36901697
Digital expression profile of immune checkpoint genes in medulloblastomas identifies CD24 and CD276 as putative immunotherapy targets., PMID:36825029
The role of intestinal immune cells and matrix metalloproteinases in inflammatory bowel disease., PMID:36733384
Trypanosoma cruzi-specific CD8+ T cells and other immunological hallmarks in chronic Chagas cardiomyopathy: Two decades of research., PMID:36683674
Differentially Infiltrated Identification of Novel Diagnostic Biomarkers Associated with Immune Infiltration in Nasopharyngeal Carcinoma., PMID:36438903
CD160 receptor in CLL: Current state and future avenues., PMID:36420268
A prognostic gene signature for gastric cancer and the immune infiltration-associated mechanism underlying the signature gene, PLG., PMID:36376702
[Expression of CD160 in natural killer (NK) cells from patients with active tuberculosis and its relationship with cell functions]., PMID:36163624
Identification of senescence-related molecular subtypes and key genes for prostate cancer., PMID:36124532
CD160 Promotes NK Cell Functions by Upregulating Glucose Metabolism and Negatively Correlates With HIV Disease Progression., PMID:36110864
Potential biomarkers for predicting the overall survival outcome of kidney renal papillary cell carcinoma: an analysis of ferroptosis-related LNCRNAs., PMID:36104680
BTLA inhibition has a dominant role in the cis-complex of BTLA and HVEM., PMID:36081508
Induction of a colitogenic phenotype in Th1-like cells depends on interleukin-23 receptor signaling., PMID:36070768
For research use only. Not for human or drug use.
