Catalog No.
RHA59101
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
ZBTB24, KIAA0441, ZNF450, Zinc finger and BTB domain-containing protein 24, Zinc finger protein 450
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O43167
Applications
ELISA, IF, IP
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
C245
The ICF2 gene Zbtb24 specifically regulates the differentiation of B1 cells via promoting heme synthesis., PMID:39277732
Exploring the intersection of epigenetics, DNA repair, and immunology from studies of ICF syndrome, an inborn error of immunity., PMID:38799442
Enhanced CD19 activity in B cells contributes to immunodeficiency in mice deficient in the ICF syndrome gene Zbtb24., PMID:37990035
Characterization of a mouse model of ICF syndrome reveals enhanced CD19 activation in inducing hypogammaglobulinemia., PMID:36945532
Autoimmunity in monogenic combined immune deficiencies with associated or syndromic features., PMID:36544766
T Cell Repertoire Abnormality in Immunodeficiency Patients with DNA Repair and Methylation Defects., PMID:34825286
Clinical, Immunologic and Molecular Spectrum of Patients with Immunodeficiency, Centromeric Instability, and Facial Anomalies (ICF) Syndrome: A Systematic Review., PMID:32533820
Structural basis of specific DNA binding by the transcription factor ZBTB24., PMID:31226215
ZBTB24 regulates the apoptosis of human T cells via CDCA7/TRAIL-receptor axis., PMID:31030944
Progressive Immunodeficiency with Gradual Depletion of B and CD4⁺ T Cells in Immunodeficiency, Centromeric Instability and Facial Anomalies Syndrome 2 (ICF2)., PMID:30987377
Three Types of Immunodeficiency, Centromeric Instability, and Facial Anomalies (ICF) Syndrome Identified by Whole-Exome Sequencing in Saudi Hypogammaglobulinemia Patients: Clinical, Molecular, and Cytogenetic Features., PMID:30511102
Expanding the mutation spectrum in ICF syndrome: Evidence for a gender bias in ICF2., PMID:28128455
Downregulation of ZBTB24 hampers the G0/1- to S-phase cell-cycle transition via upregulating the expression of IRF-4 in human B cells., PMID:27098601
Genetic, Cellular and Clinical Features of ICF Syndrome: a French National Survey., PMID:26851945
Germline genes hypomethylation and expression define a molecular signature in peripheral blood of ICF patients: implications for diagnosis and etiology., PMID:24742017
Heterogeneous clinical presentation in ICF syndrome: correlation with underlying gene defects., PMID:23486536
Oxidized LDL immune complexes and oxidized LDL differentially affect the expression of genes involved with inflammation and survival in human U937 monocytic cells., PMID:18597759
For research use only. Not for human or drug use.
