Catalog No.
RHA59101
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Applications
ELISA, IF, IP
Target
ZBTB24, KIAA0441, ZNF450, Zinc finger and BTB domain-containing protein 24, Zinc finger protein 450
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O43167
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
C245
Note
For research use only.
Oxidized LDL immune complexes and oxidized LDL differentially affect the expression of genes involved with inflammation and survival in human U937 monocytic cells., PMID:18597759
Heterogeneous clinical presentation in ICF syndrome: correlation with underlying gene defects., PMID:23486536
Germline genes hypomethylation and expression define a molecular signature in peripheral blood of ICF patients: implications for diagnosis and etiology., PMID:24742017
Genetic, Cellular and Clinical Features of ICF Syndrome: a French National Survey., PMID:26851945
Downregulation of ZBTB24 hampers the G0/1- to S-phase cell-cycle transition via upregulating the expression of IRF-4 in human B cells., PMID:27098601
Expanding the mutation spectrum in ICF syndrome: Evidence for a gender bias in ICF2., PMID:28128455
Three Types of Immunodeficiency, Centromeric Instability, and Facial Anomalies (ICF) Syndrome Identified by Whole-Exome Sequencing in Saudi Hypogammaglobulinemia Patients: Clinical, Molecular, and Cytogenetic Features., PMID:30511102
Progressive Immunodeficiency with Gradual Depletion of B and CD4⁺ T Cells in Immunodeficiency, Centromeric Instability and Facial Anomalies Syndrome 2 (ICF2)., PMID:30987377
ZBTB24 regulates the apoptosis of human T cells via CDCA7/TRAIL-receptor axis., PMID:31030944
Structural basis of specific DNA binding by the transcription factor ZBTB24., PMID:31226215
Clinical, Immunologic and Molecular Spectrum of Patients with Immunodeficiency, Centromeric Instability, and Facial Anomalies (ICF) Syndrome: A Systematic Review., PMID:32533820
T Cell Repertoire Abnormality in Immunodeficiency Patients with DNA Repair and Methylation Defects., PMID:34825286
Autoimmunity in monogenic combined immune deficiencies with associated or syndromic features., PMID:36544766
Characterization of a mouse model of ICF syndrome reveals enhanced CD19 activation in inducing hypogammaglobulinemia., PMID:36945532
Enhanced CD19 activity in B cells contributes to immunodeficiency in mice deficient in the ICF syndrome gene Zbtb24., PMID:37990035
Exploring the intersection of epigenetics, DNA repair, and immunology from studies of ICF syndrome, an inborn error of immunity., PMID:38799442
The ICF2 gene Zbtb24 specifically regulates the differentiation of B1 cells via promoting heme synthesis., PMID:39277732
For research use only. Not for human or drug use.
