Anti-ANGPT1 Polyclonal Antibody

Catalog No.

PHH08201

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human ANGPT1 (Pro282-Arg402).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Angiopoietin-1,KIAA0003,ANGPT1,ANG-1

Purification

Purified by antigen affinity column.

Accession

Q15389

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Status of alternative angiogenic pathways in glioblastoma resected under and after bevacizumab treatment., PMID:38619734

Human Keratinocytes and Fibroblasts Co-Cultured on Silk Fibroin Scaffolds Exosomally Overrelease Angiogenic and Growth Factors., PMID:37508492

Detrimental effects of PCSK9 loss-of-function in the pediatric host response to sepsis are mediated through independent influence on Angiopoietin-1., PMID:37365661

Detrimental effects of PCSK9 loss-of-function in the pediatric host response to sepsis are mediated through independent influence on Angiopoietin-1., PMID:36778250

Akt1-dependent expression of angiopoietin 1 and 2 in vascular smooth muscle cells leads to vascular stabilization., PMID:35931736

Effect of Novel Biotherapeutic Elevating Angiopoietin 1 on Progression of Diabetic Nephropathy in Diabetic/Obese Mice., PMID:35779860

Structural insights into the clustering and activation of Tie2 receptor mediated by Tie2 agonistic antibody., PMID:34725372

Apelin Promotes Endothelial Progenitor Cell Angiogenesis in Rheumatoid Arthritis Disease via the miR-525-5p/Angiopoietin-1 Pathway., PMID:34659230

Interleukin-6 as an enhancer of anti-angiogenic therapy for ovarian clear cell carcinoma., PMID:33833265

Genetic Variants of ANGPT1, CD39, FGF2 and MMP9 Linked to Clinical Outcome of Bevacizumab Plus Chemotherapy for Metastatic Colorectal Cancer., PMID:33573134

Genome-Wide Association Study Identifies Genomic Loci Associated With Neurotransmitter Concentration in Cattle., PMID:32292413

Angiopoietin-1 accelerates Alzheimer's disease via FOXA2/PEN2/APP pathway in APP/PS1 mice., PMID:32061671

Identification of Astrocytoma Blood Serum Protein Profile., PMID:31861636

High levels of Notch intracellular cleaved domain are associated with stemness and reduced bevacizumab efficacy in patients with advanced colon cancer., PMID:31578584

Rapid Development of Glaucoma Via ITV Nonselective ANGPT 1/2 Antibody: A Potential Role for ANGPT/TIE2 Signaling in Primate Aqueous Humor Outflow., PMID:31574535

Tie-2/Angiopoietin pathway modulation as a therapeutic strategy for retinal disease., PMID:31513439

Dl-3-n-Butylphthalide regulates the Ang-1/Ang-2/Tie-2 signaling axis to promote neovascularization in chronic cerebral hypoperfusion., PMID:30897537

Tie2 activation promotes choriocapillary regeneration for alleviating neovascular age-related macular degeneration., PMID:30788433

Coculture with bone marrow‑derived mesenchymal stem cells attenuates inflammation and apoptosis in lipopolysaccharide‑stimulated alveolar epithelial cells via enhanced secretion of keratinocyte growth factor and angiopoietin‑1 modulating the Toll‑like receptor‑4 signal pathway., PMID:30628710

Angiopoietin-1/Tie2 signaling pathway contributes to the therapeutic effect of thymosin β4 on diabetic peripheral neuropathy., PMID:30326249

Angiopoietin-2 exacerbates cardiac hypoxia and inflammation after myocardial infarction., PMID:30295643

The neurotrophic effects of different human dental mesenchymal stem cells., PMID:28974767

Impaired angiopoietin/Tie2 signaling compromises Schlemm's canal integrity and induces glaucoma., PMID:28920924

Homocysteine Facilitates Prominent Polygonal Angiogenetic Networks of a Choroidal Capillary Sprouting Model., PMID:28806447

Intravenous neutralization of vascular endothelial growth factor reduces vascular function/permeability of the ovary and prevents development of OHSS-like symptoms in rhesus monkeys., PMID:28683759

Angiopoietin-1 enhances neutrophil chemotaxis in vitro and migration in vivo through interaction with CD18 and release of CCL4., PMID:28539655

[Effects of TNF-alpha/NF-kappa B signaling pathway on etanercept alleviating rheumatoid arthritis]., PMID:29926646

Complementary actions of dopamine D2 receptor agonist and anti-vegf therapy on tumoral vessel normalization in a transgenic mouse model., PMID:28152577

Germline Genetic Variants in TEK, ANGPT1, ANGPT2, MMP9, FGF2 and VEGFA Are Associated with Pathologic Complete Response to Bevacizumab in Breast Cancer Patients., PMID:28045923

Role of vascular endothelial growth factor in inducing production of angiopoetin-1 - in vivo study in Fisher rats., PMID:29517203

The Osmopressor-Induced Angiopoietin-1 Secretion in Plasma and Subsequent Activation of the Tie-2/Akt/eNOS Signaling Pathway in Red Blood Cell., PMID:28034894

Hydroxysafflor Yellow A Promotes Angiogenesis via the Angiopoietin 1/ Tie-2 Signaling Pathway., PMID:27894114

Angiogenic factors are associated with multiple sclerosis., PMID:27887749

Aflibercept and Ang1 supplementation improve neoadjuvant or adjuvant chemotherapy in a preclinical model of resectable breast cancer., PMID:27841282

Role of angiopoietin-2 in infection - A double-edged sword?, PMID:27038015

Induction of Angiogenesis by a Type III Phosphodiesterase Inhibitor, Cilostazol, Through Activation of Peroxisome Proliferator-Activated Receptor-γ and cAMP Pathways in Vascular Cells., PMID:26769045

miR-92a regulates angiogenic activity of adipose-derived mesenchymal stromal cells., PMID:26477824

Topical Application of Insulin Accelerates Vessel Maturation of Wounds by Regulating Angiopoietin-1 in Diabetic Mice., PMID:26349856

Characterization of cells from patient-derived fibrovascular membranes in proliferative diabetic retinopathy., PMID:26120272

[Effects of adenovirus-delivered angiopoietin-1 siRNA on expression of matrix metalloproteinases in rats with acute lung injury induced by phosgene]., PMID:25511264

Inhibition of angiopoietin-1 (ANGPT1) affects vascular integrity in ovarian hyperstimulation syndrome (OHSS)., PMID:25485810

[Research advances on anti-ANGPT2 antibody in acute myeloid leukemia]., PMID:25338607

The angiopoietin1-Akt pathway regulates barrier function of the cultured spinal cord microvascular endothelial cells through Eps8., PMID:25149679

Angiopoietins promote ovarian cancer progression by establishing a procancer microenvironment., PMID:25043619

Inhibition of Ninjurin 1 restores erectile function through dual angiogenic and neurotrophic effects in the diabetic mouse., PMID:24979788

The combination of circulating Ang1 and Tie2 levels predicts progression-free survival advantage in bevacizumab-treated patients with ovarian cancer., PMID:24947924

Sonic hedgehog secreted by neurons regulates angiopoietin expression in neighboring fibroblasts., PMID:24807580

Angiopoietin1 inhibits mast cell activation and protects against anaphylaxis., PMID:24586553

High-circulating Tie2 Is Associated With Pathologic Complete Response to Chemotherapy and Antiangiogenic Therapy in Breast Cancer., PMID:24577164

Angiopoietins modulate endothelial adaptation, glomerular and podocyte hypertrophy after uninephrectomy., PMID:24367525

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