Catalog No.
PHH06301
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human RALBP1 (Arg403-Met499).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Dinitrophenyl S-glutathione ATPase,RLIP1,RalBP1,DNP-SG ATPase,76 kDa Ral-interacting protein,Ral-interacting protein 1,RalA-binding protein 1,RLIP76,RALBP1
Purification
Purified by antigen affinity column.
Accession
Q15311
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Enhancing carboplatin sensitivity in ovarian cancer cells by blocking the mercapturic acid pathway transporter., PMID:39051454
Astrocyte-Derived TNF-α-Activated Platelets Promote Cerebral Ischemia/Reperfusion Injury by Regulating the RIP1/RIP3/AKT Signaling Pathway., PMID:35781632
Casp8 acts through A20 to inhibit PD-L1 expression: The mechanism and its implication in immunotherapy., PMID:33934451
RLIP depletion induces apoptosis associated with inhibition of JAK2/STAT3 signaling in melanoma cells., PMID:33623991
Prevention of mammary carcinogenesis in MMTV-neu mice by targeting RLIP., PMID:33544936
Rlip Depletion Suppresses Growth of Breast Cancer., PMID:32498332
Dynamic alterations of genome and transcriptome in KRAS G13D mutant CRC PDX model treated with cetuximab., PMID:32404198
Synergistic efficacy of RLIP inhibition and 2'-hydroxyflavanone against DMBA-induced mammary carcinogenesis in SENCAR mice., PMID:31006917
RLIP inhibition suppresses breast-to-lung metastasis., PMID:30684594
Anticancer activity of 2'-hydroxyflavanone towards lung cancer., PMID:30546837
Metastasis of breast tumor cells to brain is suppressed by targeting RLIP alone and in combination with 2'-Hydroxyflavanone., PMID:30223070
2'-Hydroxyflavanone inhibits in vitro and in vivo growth of breast cancer cells by targeting RLIP76., PMID:30136444
Rlip depletion prevents spontaneous neoplasia in TP53 null mice., PMID:29572430
RLIP76 Inhibition: A Promising Developmental Therapy for Neuroblastoma., PMID:28386633
P-selectin-mediated LOX expression promotes insulinoma growth in Rip1-Tag2 mice by increasing tissue stiffness., PMID:27877081
24-Hydroxycholesterol participates in pancreatic neuroendocrine tumor development., PMID:27671648
The matricellular protein CYR61 interferes with normal pancreatic islets architecture and promotes pancreatic neuroendocrine tumor progression., PMID:26625209
The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling., PMID:26525107
TAK1 inhibition-induced RIP1-dependent apoptosis in murine macrophages relies on constitutive TNF-α signaling and ROS production., PMID:26381601
Genes involved in pericyte-driven tumor maturation predict treatment benefit of first-line FOLFIRI plus bevacizumab in patients with metastatic colorectal cancer., PMID:25069475
Smac mimetic and glucocorticoids synergize to induce apoptosis in childhood ALL by promoting ripoptosome assembly., PMID:24855207
Differential regulation of inflammation and apoptosis in Fas-resistant hepatocyte-specific Bid-deficient mice., PMID:24681344
Micrometastasis expressing insulin arise in lung and spleen at advanced stage of rip1-tag2 transgenic mice., PMID:24520211
Identification of a human protein-derived HIV-1 fusion inhibitor targeting the gp41 fusion core structure., PMID:23741527
RIP1 mediates the protection of geldanamycin on neuronal injury induced by oxygen-glucose deprivation combined with zVAD in primary cortical neurons., PMID:21985437
Gender disparity in susceptibility to oxidative stress and apoptosis induced by autoantibodies specific to RLIP76 in vascular cells., PMID:21671802
RLIP76: a versatile transporter and an emerging target for cancer therapy., PMID:20097178
Rlip76 transports sunitinib and sorafenib and mediates drug resistance in kidney cancer., PMID:19626587
RLIP76: a target for kidney cancer therapy., PMID:19417134
Regression of prostate cancer xenografts by RLIP76 depletion., PMID:19073149
RLIP76 and Cancer., PMID:18628450
Vascular targeting of anti-CD40 antibodies and IL-2 into autochthonous tumors enhances immunotherapy in mice., PMID:18398504
Autoantibodies to the C-terminal subunit of RLIP76 induce oxidative stress and endothelial cell apoptosis in immune-mediated vascular diseases and atherosclerosis., PMID:17993611
Identification of differentially expressed proteins in ovarian cancer using high-density protein microarrays., PMID:17954908
The non-ABC drug transporter RLIP76 (RALBP-1) plays a major role in the mechanisms of drug resistance., PMID:17504221
Regression of lung and colon cancer xenografts by depleting or inhibiting RLIP76 (Ral-binding protein 1)., PMID:17483352
Lack of support for a role for RLIP76 (RALBP1) in response to treatment or predisposition to epilepsy., PMID:17437410
RALBP1/RLIP76 mediates multidrug resistance., PMID:17143522
Regression of melanoma in a murine model by RLIP76 depletion., PMID:16489041
Depletion of RLIP76 sensitizes lung cancer cells to doxorubicin., PMID:15950949
RLIP76 transports vinorelbine and mediates drug resistance in non-small cell lung cancer., PMID:15705900
RLIP76 (RALBP1)-mediated transport of leukotriene C4 (LTC4) in cancer cells: implications in drug resistance., PMID:15386349
Mechanisms and physiological significance of the transport of the glutathione conjugate of 4-hydroxynonenal in human lens epithelial cells., PMID:12882793
Lipid peroxidation and cell cycle signaling: 4-hydroxynonenal, a key molecule in stress mediated signaling., PMID:12833161
Role of RLIP76 in lung cancer doxorubicin resistance: III. Anti-RLIP76 antibodies trigger apoptosis in lung cancer cells and synergistically increase doxorubicin cytotoxicity., PMID:12632061
Role of RLIP76 in lung cancer doxorubicin resistance: II. Doxorubicin transport in lung cancer by RLIP76., PMID:12632060
Role of RLIP76 in lung cancer doxorubicin resistance: I. The ATPase activity of RLIP76 correlates with doxorubicin and 4-hydroxynonenal resistance in lung cancer cells., PMID:12527936
RLIP76 is the major ATP-dependent transporter of glutathione-conjugates and doxorubicin in human erythrocytes., PMID:11437348
Regulation of complex formation of POB1/epsin/adaptor protein complex 2 by mitotic phosphorylation., PMID:10764745
For research use only. Not for human or drug use.
