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Anti-RALBP1 Polyclonal Antibody

Catalog #:   PHH06301 Specific References (49) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q15311
Overview

Catalog No.

PHH06301

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human RALBP1 (Arg403-Met499).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Dinitrophenyl S-glutathione ATPase,RLIP1,RalBP1,DNP-SG ATPase,76 kDa Ral-interacting protein,Ral-interacting protein 1,RalA-binding protein 1,RLIP76,RALBP1

Purification

Purified by antigen affinity column.

Accession

Q15311

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • WESTERN BLOT
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with RALBP1 antibody (PHH06301) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 14 kDa
    Observed MW: 14 kDa
References

Enhancing carboplatin sensitivity in ovarian cancer cells by blocking the mercapturic acid pathway transporter., PMID:39051454

Astrocyte-Derived TNF-α-Activated Platelets Promote Cerebral Ischemia/Reperfusion Injury by Regulating the RIP1/RIP3/AKT Signaling Pathway., PMID:35781632

Casp8 acts through A20 to inhibit PD-L1 expression: The mechanism and its implication in immunotherapy., PMID:33934451

RLIP depletion induces apoptosis associated with inhibition of JAK2/STAT3 signaling in melanoma cells., PMID:33623991

Prevention of mammary carcinogenesis in MMTV-neu mice by targeting RLIP., PMID:33544936

Rlip Depletion Suppresses Growth of Breast Cancer., PMID:32498332

Dynamic alterations of genome and transcriptome in KRAS G13D mutant CRC PDX model treated with cetuximab., PMID:32404198

Synergistic efficacy of RLIP inhibition and 2'-hydroxyflavanone against DMBA-induced mammary carcinogenesis in SENCAR mice., PMID:31006917

RLIP inhibition suppresses breast-to-lung metastasis., PMID:30684594

Anticancer activity of 2'-hydroxyflavanone towards lung cancer., PMID:30546837

Metastasis of breast tumor cells to brain is suppressed by targeting RLIP alone and in combination with 2'-Hydroxyflavanone., PMID:30223070

2'-Hydroxyflavanone inhibits in vitro and in vivo growth of breast cancer cells by targeting RLIP76., PMID:30136444

Rlip depletion prevents spontaneous neoplasia in TP53 null mice., PMID:29572430

RLIP76 Inhibition: A Promising Developmental Therapy for Neuroblastoma., PMID:28386633

P-selectin-mediated LOX expression promotes insulinoma growth in Rip1-Tag2 mice by increasing tissue stiffness., PMID:27877081

24-Hydroxycholesterol participates in pancreatic neuroendocrine tumor development., PMID:27671648

The matricellular protein CYR61 interferes with normal pancreatic islets architecture and promotes pancreatic neuroendocrine tumor progression., PMID:26625209

The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling., PMID:26525107

TAK1 inhibition-induced RIP1-dependent apoptosis in murine macrophages relies on constitutive TNF-α signaling and ROS production., PMID:26381601

Genes involved in pericyte-driven tumor maturation predict treatment benefit of first-line FOLFIRI plus bevacizumab in patients with metastatic colorectal cancer., PMID:25069475

Smac mimetic and glucocorticoids synergize to induce apoptosis in childhood ALL by promoting ripoptosome assembly., PMID:24855207

Differential regulation of inflammation and apoptosis in Fas-resistant hepatocyte-specific Bid-deficient mice., PMID:24681344

Micrometastasis expressing insulin arise in lung and spleen at advanced stage of rip1-tag2 transgenic mice., PMID:24520211

Identification of a human protein-derived HIV-1 fusion inhibitor targeting the gp41 fusion core structure., PMID:23741527

RIP1 mediates the protection of geldanamycin on neuronal injury induced by oxygen-glucose deprivation combined with zVAD in primary cortical neurons., PMID:21985437

Gender disparity in susceptibility to oxidative stress and apoptosis induced by autoantibodies specific to RLIP76 in vascular cells., PMID:21671802

RLIP76: a versatile transporter and an emerging target for cancer therapy., PMID:20097178

Rlip76 transports sunitinib and sorafenib and mediates drug resistance in kidney cancer., PMID:19626587

RLIP76: a target for kidney cancer therapy., PMID:19417134

Regression of prostate cancer xenografts by RLIP76 depletion., PMID:19073149

RLIP76 and Cancer., PMID:18628450

Vascular targeting of anti-CD40 antibodies and IL-2 into autochthonous tumors enhances immunotherapy in mice., PMID:18398504

Autoantibodies to the C-terminal subunit of RLIP76 induce oxidative stress and endothelial cell apoptosis in immune-mediated vascular diseases and atherosclerosis., PMID:17993611

Identification of differentially expressed proteins in ovarian cancer using high-density protein microarrays., PMID:17954908

The non-ABC drug transporter RLIP76 (RALBP-1) plays a major role in the mechanisms of drug resistance., PMID:17504221

Regression of lung and colon cancer xenografts by depleting or inhibiting RLIP76 (Ral-binding protein 1)., PMID:17483352

Lack of support for a role for RLIP76 (RALBP1) in response to treatment or predisposition to epilepsy., PMID:17437410

RALBP1/RLIP76 mediates multidrug resistance., PMID:17143522

Regression of melanoma in a murine model by RLIP76 depletion., PMID:16489041

Depletion of RLIP76 sensitizes lung cancer cells to doxorubicin., PMID:15950949

RLIP76 transports vinorelbine and mediates drug resistance in non-small cell lung cancer., PMID:15705900

RLIP76 (RALBP1)-mediated transport of leukotriene C4 (LTC4) in cancer cells: implications in drug resistance., PMID:15386349

Mechanisms and physiological significance of the transport of the glutathione conjugate of 4-hydroxynonenal in human lens epithelial cells., PMID:12882793

Lipid peroxidation and cell cycle signaling: 4-hydroxynonenal, a key molecule in stress mediated signaling., PMID:12833161

Role of RLIP76 in lung cancer doxorubicin resistance: III. Anti-RLIP76 antibodies trigger apoptosis in lung cancer cells and synergistically increase doxorubicin cytotoxicity., PMID:12632061

Role of RLIP76 in lung cancer doxorubicin resistance: II. Doxorubicin transport in lung cancer by RLIP76., PMID:12632060

Role of RLIP76 in lung cancer doxorubicin resistance: I. The ATPase activity of RLIP76 correlates with doxorubicin and 4-hydroxynonenal resistance in lung cancer cells., PMID:12527936

RLIP76 is the major ATP-dependent transporter of glutathione-conjugates and doxorubicin in human erythrocytes., PMID:11437348

Regulation of complex formation of POB1/epsin/adaptor protein complex 2 by mitotic phosphorylation., PMID:10764745

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-RALBP1 Polyclonal Antibody [PHH06301]
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