Catalog No.
YHN07101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln23-Met212
Predicted molecular weight
23.76 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9HBJ0
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Placenta-specific protein 1, PLAC1
Plac1+ Tumor Cell-Treg Interplay Supports Tumorigenesis and Progression of Head and Neck Cancer., PMID:40056047
Identification of PLAC1 as a prognostic biomarker and molecular target in clear cell renal cell carcinoma., PMID:39814247
PLAC1 augments the malignant phenotype of cervical cancer through the mTOR/HIF-1α/Snail signaling pathway., PMID:39549936
Placental gene therapy in nonhuman primates: a pilot study of maternal, placental, and fetal response to non-viral, polymeric nanoparticle delivery of IGF1., PMID:39499161
Nanoparticle-mediated delivery of placental gene therapy via uterine artery catheterization in a pregnant rhesus macaque., PMID:39362807
Production and characterization of a panel of anti-mouse placenta-specific protein 1 (plac1) monoclonal antibodies., PMID:39332465
Identification of placenta-specific protein 1 (PLAC-1) expression on human PC-3 cell line-derived prostate cancer stem cells compared to the tumor parental cells., PMID:38943028
Effect of Early pregnancy associated protein-1 on Spike protein and ACE2 interactions: Implications in SARS Cov-2 vertical transmission., PMID:38788480
A Novel Four‑Gene Biomarker for Tobacco Smoking-Induced Colorectal Cancer Progression., PMID:38602278
Changes in plasma PLAC-1 concentration and its expression during early-mid pregnancy in bovine placental tissues - a pilot study., PMID:38378537
Maternal, placental and fetal response to a non-viral, polymeric nanoparticle gene therapy in nonhuman primates., PMID:38168281
Differential expression of PLAC1 and Netrin-1 in liver metastasis of colorectal cancer and its predictive value., PMID:37568074
Investigation of Expression Profile of Placenta-specific 1 (PLAC1) in Acute Myeloid and Lymphoid Leukemias., PMID:37538244
Peptide-functionalized zinc oxide nanoparticles for the selective targeting of breast cancer expressing placenta-specific protein 1., PMID:37210795
Identification of Cancer/Testis Antigens Related to Gastric Cancer Prognosis Based on Co-Expression Network and Integrated Transcriptome Analyses., PMID:37057240
The Oncogenic Theory of Preeclampsia: Is Amniotic Mesenchymal Stem Cells-Derived PLAC1 Involved?, PMID:36835024
Peptide-functionalized graphene oxide quantum dots as colorectal cancer theranostics., PMID:36274405
Immunization with placenta-specific 1 (plac1) induces potent anti-tumor responses and prolongs survival in a mouse model of melanoma., PMID:36084365
Optimization of Expression and Purification of Recombinant Mouse plac1., PMID:35509359
Sex-specific effects of bisphenol A on the signaling pathway of ESRRG in the human placenta†., PMID:35220427
The Synthetic Curcumin Analog HO-3867 Rescues Suppression of PLAC1 Expression in Ovarian Cancer Cells., PMID:34577642
Placenta-specific protein 1 (PLAC1) expression is significantly down-regulated in preeclampsia via a hypoxia-mediated mechanism., PMID:34565269
PLAC1 is an independent predictor of poor survival, and promotes cell proliferation and invasion in cervical cancer., PMID:34523695
PLAC1 affects cell to cell communication by interacting with the desmosome complex., PMID:34118612
Placenta-specific protein 1 promotes cell proliferation via the AKT/GSK-3β/cyclin D1 signaling pathway in gastric cancer., PMID:34110086
Expression level of PLAC1 in osteosarcoma patients and its regulatory effect on the development of osteosarcoma., PMID:34077010
PLAC1 Regulates the Occurrence of Fetal Growth Restriction by Inhibiting the Apoptosis of Trophoblast Cells., PMID:33941557
Insulin-like growth factor 1 signaling in the placenta requires endothelial nitric oxide synthase to support trophoblast function and normal fetal growth., PMID:33621475
Expression of placenta-specific 1 and its potential for eliciting anti-tumor helper T-cell responses in head and neck squamous cell carcinoma., PMID:33457076
Plac1 promotes nasopharyngeal carcinoma cells proliferation, migration and invasion via Furin/NICD/PTEN pathway., PMID:33418237
Intermittent fasting from dawn to sunset for four consecutive weeks induces anticancer serum proteome response and improves metabolic syndrome., PMID:33110154
Discovery of a potential biomarker for immunotherapy of melanoma: PLAC1 as an emerging target., PMID:33106058
High expression of PLAC1 in colon cancer as a predictor of poor prognosis: A study based on TCGA data., PMID:32827679
Placenta-specific protein 1 enhances liver metastatic potential and is associated with the PI3K/AKT/NF-κB signaling pathway in colorectal cancer., PMID:32701605
PLAC1 is essential for FGF7/FGFRIIIb-induced Akt-mediated cancer cell proliferation., PMID:32499871
Syncytiotrophoblast extracellular microvesicle profiles in maternal circulation for noninvasive diagnosis of preeclampsia., PMID:32286341
CRISPR/Cas9-Mediated Genome Editing Reveals Oosp Family Genes are Dispensable for Female Fertility in Mice., PMID:32231122
Expression of Human Placenta-specific 1 (PLAC1) in CHO-K1 Cells., PMID:32153735
Nanoparticle mediated increased insulin-like growth factor 1 expression enhances human placenta syncytium function., PMID:32090963
In silico Evaluation of PLAC1-fliC As a Chimeric Vaccine against Breast Cancer., PMID:31952435
Placenta specific protein-1 in recurrent pregnancy loss and in In Vitro Fertilisation failure: a prospective observational case-control study., PMID:31791163
Declined placental PLAC1 expression is involved in preeclampsia., PMID:31689783
PLAC1: biology and potential application in cancer immunotherapy., PMID:31165204
Expression profiling of plac1 in murine cancer cell lines., PMID:30932401
Association of Higher Maternal Serum Levels of Plac1 Protein with Intrauterine Growth Restriction., PMID:30267394
Placenta-specific 1 regulates oocyte meiosis and fertilization through furin., PMID:29723063
Cancer/testis antigen-Plac1 promotes invasion and metastasis of breast cancer through Furin/NICD/PTEN signaling pathway., PMID:29704427
Maternal placi protein levels in early- and late-onset preeclampsia., PMID:29664550
Plac1 Is a Key Regulator of the Inflammatory Response and Immune Tolerance In Mammary Tumorigenesis., PMID:29632317
PLAC1-specific TCR-engineered T cells mediate antigen-specific antitumor effects in breast cancer., PMID:29556312