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Anti-AGER Polyclonal Antibody

Catalog #:   PHH01901 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q15109
Overview

Catalog No.

PHH01901

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human AGER (Ile91-Asp274).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Receptor for advanced glycosylation end products,Advanced glycosylation end product-specific receptor,AGER,RAGE

Purification

Purified by antigen affinity column.

Accession

Q15109

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western Blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with AGER antibody (PHH01901) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 22 kDa
    Observed MW: 22 kDa
References

Sex Differences in Long COVID., PMID:39841477

2024 Update of the RECOVER-Adult Long COVID Research Index., PMID:39693079

An anti-RAGE chimeric antibody alleviates CCl4-induced liver fibrosis via RAGE/NF-kB pathway in mice., PMID:39657505

Fc-enhanced anti-CTLA-4 depletes tumor-infiltrating regulatory T cells to augment immune effects of androgen ablation in high-risk prostate cancer., PMID:39314954

Molecular dynamics simulation of the brain-isolated single-domain antibody/nanobody from camels through in vivo phage display screening., PMID:39290991

Extracellular NCOA4 is a mediator of septic death by activating the AGER-NFKB pathway., PMID:38916095

Insight into the Interplay of Gd-IgA1, HMGB1, RAGE and PCDH1 in IgA Vasculitis (IgAV)., PMID:38673968

Lupus autoantibodies initiate neuroinflammation sustained by continuous HMGB1:RAGE signaling and reversed by increased LAIR-1 expression., PMID:38448779

Neoadjuvant durvalumab plus radiation versus durvalumab alone in stages I-III non-small cell lung cancer: survival outcomes and molecular correlates of a randomized phase II trial., PMID:38114518

Specific serum autoantibodies predict the development and progression of Alzheimer's disease with high accuracy., PMID:37989443

HMGB1-RAGE axis contributes to myocardial ischemia/reperfusion injury via regulation of cardiomyocyte autophagy and apoptosis in diabetic mice., PMID:37768929

Human intestine and placenta exhibit tissue-specific expression of RAGE isoforms., PMID:37533998

Oxidised IL-33 drives COPD epithelial pathogenesis via ST2-independent RAGE/EGFR signalling complex., PMID:37442582

Evaluating the effect of measles and rubella mass vaccination campaigns on seroprevalence in India: a before-and-after cross-sectional household serosurvey in four districts, 2018-2020., PMID:36240831

LRG1 destabilizes tumor vessels and restricts immunotherapeutic potency., PMID:35590198

Soluble RAGE attenuates Ang II-induced arterial calcification via inhibiting AT1R-HMGB1-RAGE axis., PMID:35278873

Heparan sulfate-dependent RAGE oligomerization is indispensable for pathophysiological functions of RAGE., PMID:35137686

Generation, biochemical characterizations and validation of potent nanobodies derived from alpaca specific for human receptor of advanced glycation end product., PMID:34653677

High potency STING agonists engage unique myeloid pathways to reverse pancreatic cancer immune privilege., PMID:34341132

RAGE and αVβ3-integrin are essential for suPAR signaling in podocytes., PMID:34166766

SARS-CoV-2 proteins regulate inflammatory, thrombotic and diabetic responses in human arterial fibroblasts., PMID:33895357

HMGB1/RAGE/TLR4 axis and glutamate as novel targets for PCSK9 inhibitor in high fat cholesterol diet induced cognitive impairment and amyloidosis., PMID:33667517

Pretreatment of aged mice with retinoic acid supports alveolar regeneration via upregulation of reciprocal PDGFA signalling., PMID:33479039

Integrated Single-Cell RNA-Sequencing Analysis of Aquaporin 5-Expressing Mouse Lung Epithelial Cells Identifies GPRC5A as a Novel Validated Type I Cell Surface Marker., PMID:33187367

HMGB1 and its membrane receptors as therapeutic targets in an intravesical substance P-induced bladder pain syndrome mouse model., PMID:32222337

Integrated transcriptomic correlation network analysis identifies COPD molecular determinants., PMID:32099002

Autophagy-based unconventional secretion of HMGB1 by keratinocytes plays a pivotal role in psoriatic skin inflammation., PMID:32019420

Can the AGE/RAGE/ERK signalling pathway and the epithelial-to-mesenchymal transition interact in the pathogenesis of chronic rhinosinusitis with nasal polyps?, PMID:31988531

The Trp triad within the V-domain of the receptor for advanced glycation end products modulates folding, stability and ligand binding., PMID:31912881

Clinical Implications of Extracellular HMGA1 in Breast Cancer., PMID:31779212

TLR9 activation cooperates with T cell checkpoint blockade to regress poorly immunogenic melanoma., PMID:31771649

Discovery of IACS-8803 and IACS-8779, potent agonists of stimulator of interferon genes (STING) with robust systemic antitumor efficacy., PMID:31500996

Mumps outbreak and MMR IgG surveillance as a predictor for immunity in military trainees., PMID:31493948

Atorvastatin Blocks Advanced Glycation End Products Induced Reduction in Macrophage Cholesterol Efflux Mediated With ATP-Binding Cassette Transporters G 1., PMID:31378770

S100B Protein Stimulates Proliferation and Angiogenic Mediators Release through RAGE/pAkt/mTOR Pathway in Human Colon Adenocarcinoma Caco-2 Cells., PMID:31266264

Relevance of Receptor for Advanced Glycation end Products (RAGE) in Murine Antibody-Mediated Autoimmune Diseases., PMID:31266174

Role of Calbindin-D28k in Diabetes-Associated Advanced Glycation End-Products-Induced Renal Proximal Tubule Cell Injury., PMID:31262060

Differential Effects of Dry vs. Wet Heating of β-Lactoglobulin on Formation of sRAGE Binding Ligands and sIgE Epitope Recognition., PMID:31242665

High mobility group box 1 protein regulates osteoclastogenesis through direct actions on osteocytes and osteoclasts in vitro., PMID:31106449

Acute exposure to glycated proteins reduces cardiomyocyte contractile capacity., PMID:30997698

Alarmin HMGB1 and Soluble RAGE as New Tools to Evaluate the Risk Stratification in Patients With the Antiphospholipid Syndrome., PMID:30923525

Advanced glycation end-product 2 and Porphyromonas gingivalis lipopolysaccharide increase sclerostin expression in mouse osteocyte-like cells., PMID:30735798

Ethyl pyruvate reduces organic dust-induced airway inflammation by targeting HMGB1-RAGE signaling., PMID:30728013

Quantification of the soluble Receptor of Advanced Glycation End-Products (sRAGE) by LC-MS after enrichment by strong cation exchange (SCX) solid-phase extraction (SPE) at the protein level., PMID:30392668

Interferon-γ mediates the protective effects of soluble receptor for advanced glycation end-product in myocardial ischemia/reperfusion., PMID:30089851

Targeting RAGE as a potential therapeutic approach to Duchenne muscular dystrophy., PMID:30085099

Advanced glycation end products evoke inflammatory reactions in proximal tubular cells via autocrine production of dipeptidyl peptidase-4., PMID:30056058

Affimers as an Alternative to Antibodies in an Affinity LC-MS Assay for Quantification of the Soluble Receptor of Advanced Glycation End-Products (sRAGE) in Human Serum., PMID:30005571

Inorganic Polyphosphate Amplifies High Mobility Group Box 1-Mediated Von Willebrand Factor Release and Platelet String Formation on Endothelial Cells., PMID:29930000

Target achievement and cardiovascular event rates with Lomitapide in homozygous Familial Hypercholesterolaemia., PMID:29925433

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-AGER Polyclonal Antibody [PHH01901]
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