Monoclonal Antibodies Targeting Porcine Macrophages Are Able to Inhibit the Cell Entry of Macrophage-Tropic Viruses (PRRSV and ASFV)., PMID:40006922
Porcine peritoneal macrophages are susceptible to porcine reproductive and respiratory syndrome virus infection., PMID:39723134
Insights into genetic determinants of piglet survival during a PRRSV outbreak., PMID:39696499
The neonatal Fc receptor (FcRn) is required for porcine reproductive and respiratory syndrome virus uncoating., PMID:39651859
PRRSV infection facilitates the shedding of soluble CD163 to induce inflammatory responses., PMID:39047452
Nanobody peptide conjugate: a novel CD163 based broad neutralizing strategy against porcine reproductive and respiratory syndrome virus., PMID:38956618
Characterization of in vitro viral neutralization targets of highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) in alveolar macrophage and evaluation of protection potential against HP-PRRSV challenged based on combination of HP-PRRSV-structure proteins in vitro., PMID:38484577
Nanobodies against porcine CD163 as PRRSV broad inhibitor., PMID:37858656
Porcine Reproductive and Respiratory Syndrome (PRRS) and CD163 Resistance Polymorphic Markers: What Is the Scenario in Naturally Infected Pig Livestock in Central Italy?, PMID:37570285
A Single Amino Acid Substitution in Porcine Reproductive and Respiratory Syndrome Virus Glycoprotein 2 Significantly Impairs Its Infectivity in Macrophages., PMID:36560826
Characterization of the immune system of Ellegaard Göttingen Minipigs - An important large animal model in experimental medicine., PMID:36203585
Activating Fc Gamma Receptors and Viral Receptors Are Required for Antibody-Dependent Enhancement of Porcine Reproductive and Respiratory Syndrome Virus Infection., PMID:36136686
Immune cell composition of the bronchoalveolar lavage fluid in healthy and respiratory diseased dromedary camels., PMID:36131278
PRRS virus receptors and an alternative pathway for viral invasion., PMID:35948131
Identification of CD163 regions that are required for porcine reproductive and respiratory syndrome virus (PRRSV) infection but not for binding to viral envelope glycoproteins., PMID:35933832
Identification of MYH9 Key Domain Involved in the Entry of PRRSV Into Permissive Cells., PMID:35694306
Broad antiviral peptides against PRRSV based on novel linear epitopes on porcine CD163., PMID:35288165
CD200R family receptors are expressed on porcine monocytes and modulate the production of IL-8 and TNF-α triggered by TLR4 or TLR7 in these cells., PMID:35231818
The Isolation and Replication of African Swine Fever Virus in Primary Renal-Derived Swine Macrophages., PMID:33816588
Development of a Monoclonal Antibody Against Porcine CD163 SRCR5 Domain Which Partially Blocks Infection of PRRSV., PMID:33251273
Activation of pro- and anti-inflammatory responses in lung tissue injury during the acute phase of PRRSV-1 infection with the virulent strain Lena., PMID:32605751
Characterization of the IgA response to PRRS virus in pig oral fluids., PMID:32126095
Highly Efficient Generation of Pigs Harboring a Partial Deletion of the CD163 SRCR5 Domain, Which Are Fully Resistant to Porcine Reproductive and Respiratory Syndrome Virus 2 Infection., PMID:31440241
TNF-α induced by porcine reproductive and respiratory syndrome virus inhibits the replication of classical swine fever virus C-strain., PMID:31213269
Development and application of a porcine specific ELISA for the quantification of soluble CD163., PMID:30947982
Challenges for Porcine Reproductive and Respiratory Syndrome (PRRS) Vaccine Design: Reviewing Virus Glycoprotein Interactions with CD163 and Targets of Virus Neutralization., PMID:30658381
Pigs Lacking the Scavenger Receptor Cysteine-Rich Domain 5 of CD163 Are Resistant to Porcine Reproductive and Respiratory Syndrome Virus 1 Infection., PMID:29925651
Recombinant adenovirus-delivered soluble CD163 and sialoadhesin receptors protected pigs from porcine reproductive and respiratory syndrome virus infection., PMID:29778179
A highly pathogenic porcine reproductive and respiratory syndrome virus type 1 (PRRSV-1) strongly modulates cellular innate and adaptive immune subsets upon experimental infection., PMID:29519531
CD163 knockout pigs are fully resistant to highly pathogenic porcine reproductive and respiratory syndrome virus., PMID:29337166
Generation of murine macrophage-derived cell lines expressing porcine CD163 that support porcine reproductive and respiratory syndrome virus infection., PMID:29121904
Long-term culture and differentiation of porcine red bone marrow hematopoietic cells co-cultured with immortalized mesenchymal cells., PMID:28895865
African swine fever virus infection in Classical swine fever subclinically infected wild boars., PMID:28764692
Relative contribution of porcine reproductive and respiratory syndrome virus open reading frames 2-4 to the induction of protective immunity., PMID:28689650
Gene editing as applied to prevention of reproductive porcine reproductive and respiratory syndrome., PMID:28390179
Precision engineering for PRRSV resistance in pigs: Macrophages from genome edited pigs lacking CD163 SRCR5 domain are fully resistant to both PRRSV genotypes while maintaining biological function., PMID:28231264
Splenic CD163+ macrophages as targets of porcine reproductive and respiratory virus: Role of Siglecs., PMID:28062010
Macrophage colony-stimulating factor (CSF1) controls monocyte production and maturation and the steady-state size of the liver in pigs., PMID:27445344
Comparison of the immune competence of Turopolje, German Landrace × Turopolje, and German Landrace × Pietrain pigs after PRRSV vaccination., PMID:27185261
Treatment with a human recombinant monoclonal IgG antibody against oxidized LDL in atherosclerosis-prone pigs reduces cathepsin S in coronary lesions., PMID:27135822
Effect of polymorphisms in the GBP1, Mx1 and CD163 genes on host responses to PRRSV infection in pigs., PMID:26711047
Evaluation of the efficacy of a new modified live porcine reproductive and respiratory syndrome virus (PRRSV) vaccine (Fostera PRRS) against heterologous PRRSV challenge., PMID:24970363
Targeting dexamethasone to macrophages in a porcine endotoxemic model., PMID:23928834
Porcine reproductive and respiratory syndrome virus infection is associated with an increased number of Sn-positive and CD8-positive cells in the maternal-fetal interface., PMID:23707347
Development and characterization of two porcine monocyte-derived macrophage cell lines., PMID:23610747
Functionalized multiwalled carbon nanotubes as ultrasound contrast agents., PMID:23012426
Interaction of the European genotype porcine reproductive and respiratory syndrome virus (PRRSV) with sialoadhesin (CD169/Siglec-1) inhibits alveolar macrophage phagocytosis., PMID:22630829
Influence of N-linked glycosylation of minor proteins of porcine reproductive and respiratory syndrome virus on infectious virus recovery and receptor interaction., PMID:22537809
Different expression patterns of PRRSV mediator genes in the lung tissues of PRRSV resistant and susceptible pigs., PMID:22305867
Delivery of antigen to sialoadhesin or CD163 improves the specific immune response in pigs., PMID:21557980