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Anti-CRMP1 Polyclonal Antibody

Catalog #:   PHG74901 Specific References (24) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q14194
Overview

Catalog No.

PHG74901

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CRMP1 (Met1-Val250).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

ULIP-3,Inactive dihydropyrimidinase,CRMP1,DPYSL1,DRP-1,Dihydropyrimidinase-related protein 1,ULIP3,Collapsin response mediator protein 1,Unc-33-like phosphoprotein 3,CRMP-1

Purification

Purified by antigen affinity column.

Accession

Q14194

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western Blot
    Various lysates were subjected to SDS PAGE followed by western blot with CEMP1 antibody (PHG74901) at 1μg/ml.

    Lane 1: Mouse brain lysate
    Lane 2: Mouse Cerebellum lysate
    Lane 3: Rat brain lysate
    Lane 4: Rat Cerebellum lysate

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 62 kDa
    Observed MW: 70 kDa
  • Immunohistochemical
    Immunohistochemical analysis of mouse brain stained for CRMP1 with PHG74901.
  • Western Blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with CRMP1 antibody (PHG74901) at 1 µg/ml.

    Lane 1: Recombinant Protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 30 kDa
    Observed MW: 30 kDa
References

Maternal autoantibody profiles as biomarkers for ASD and ASD with co-occurring intellectual disability., PMID:35618885

Identification of Anti-Collapsin Response Mediator Protein 2 Antibodies in Patients With Encephalitis or Encephalomyelitis., PMID:35479088

Risk assessment analysis for maternal autoantibody-related autism (MAR-ASD): a subtype of autism., PMID:33483694

Peptides of neuron specific enolase as potential ASD biomarkers: From discovery to epitope mapping., PMID:31812776

Primary culture of mouse embryonic spinal cord neurons: cell composition and suitability for axonal regeneration studies., PMID:30621485

Design, Synthesis and Pharmacological Evalution of 1,3,4-Oxadiazole Derivatives as Collapsin Response Mediator Protein 1 (CRMP 1) Inhibitors., PMID:30398117

Differentially expressed proteins in glioblastoma multiforme identified with a nanobody-based anti-proteome approach and confirmed by OncoFinder as possible tumor-class predictive biomarker candidates., PMID:28498803

Immunohistochemistry-based prognostic biomarkers in NSCLC: novel findings on the road to clinical use?, PMID:25599124

Aggregation of the protein TRIOBP-1 and its potential relevance to schizophrenia., PMID:25333879

Dihydropyrimidinase-like protein 3 expression is negatively regulated by MYCN and associated with clinical outcome in neuroblastoma., PMID:24011394

Autism-specific maternal autoantibodies recognize critical proteins in developing brain., PMID:23838888

Proteomic, genomic and translational approaches identify CRMP1 for a role in schizophrenia and its underlying traits., PMID:22798627

Axon growth and guidance genes identify nascent, immature, and mature olfactory sensory neurons., PMID:20882566

Long form collapsin response mediator protein-1 (LCRMP-1) expression is associated with clinical outcome and lymph node metastasis in non-small cell lung cancer patients., PMID:19362386

Modulation of the expression of the invasion-suppressor CRMP-1 by cyclooxygenase-2 inhibition via reciprocal regulation of Sp1 and C/EBPalpha., PMID:18524846

Antibodies to CRMP3-4 associated with limbic encephalitis and thymoma., PMID:17403058

CRMP-5-autoantibodies in testicular cancer associated with limbic encephalitis and choreiform dyskinesias., PMID:17389803

Transient alterations in granule cell proliferation, apoptosis and migration in postnatal developing cerebellum of CRMP1-/- mice., PMID:17121542

The collapsin response mediator protein 1 (CRMP-1) and the promyelocytic leukemia zinc finger protein (PLZF) bind to UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE), the key enzyme of sialic acid biosynthesis., PMID:17118363

Differential expression of CRMP1, CRMP2A, CRMP2B, and CRMP5 in axons or dendrites of distinct neurons in the mouse brain., PMID:15834957

Involvement of collapsin response mediator proteins in the neurite extension induced by neurotrophins in dorsal root ganglion neurons., PMID:15033171

Connective tissue growth factor and its role in lung adenocarcinoma invasion and metastasis., PMID:14996858

p80 ROKalpha binding protein is a novel splice variant of CRMP-1 which associates with CRMP-2 and modulates RhoA-induced neuronal morphology., PMID:12482610

Mapping of eight testis-specific genes to mouse chromosomes., PMID:9403069

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-CRMP1 Polyclonal Antibody [PHG74901]
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