Catalog No.
                        EVV12703
                        
                                            
                                            
                                            Expression system
                        
                        Mammalian Cells                        
                                                
                                            Species
                        
                        Monkeypox virus (strain Zaire-96-I-16) (MPX)                        
                                                
                                            Protein length
                        
                        Ala2-Phe282                        
                                                
                                            Predicted molecular weight
                        
                        60.89 kDa                        
                                                
                                            Nature
                        
                        Recombinant                        
                                                
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            Endotoxin level
                        
                        Please contact with the lab for this information.                        
                                                
                                            Purity
                        
                        >90% as determined by SDS-PAGE.                        
                                                
                                            
                                            Accession
                        
                        Q8V4Z2                        
                                                
                                            
                                            Applications
                        
                        ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress                        
                                                
                                            Form
                        
                        Lyophilized                        
                                                
                                            Storage buffer
                        
                        Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.                        
                                                
                                            Reconstitution
                        
                        Reconstitute in sterile water for a stock solution.                        
                                                
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            Shipping
                        
                        In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.                        
                                                
                                            Stability and Storage
                        
                        Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.                        
                                                
                                            
                                            
                                                Alternative Names
                            H3L
                            
                                                    
                                            
                                            
                                        
                 
                
                
                                            Serological Response to Mpox and Direct Virus Detection in Asymptomatic Patient Prior to the First Diagnosed Case: A Retrospective Study of the 2022 Montpellier Epidemic., PMID:40289589
                                            Monkeypox virus H3L protein as the target antigen for developing neutralizing antibody and serological assay., PMID:40172630
                                            A Hybrid Plasmonic Nanoplatform for One-Pot DNA and Antibody Detection of Hepatitis B, Monkeypox, and Associated Infections., PMID:40143629
                                            Immunogenicity of monkeypox virus surface proteins and cross-reactive antibody responses in vaccinated and infected individuals: implications for vaccine and therapeutic development., PMID:39994775
                                            Glycosylation profiling of monkeypox virus structural proteins with poly Ser-Arg materials., PMID:39831787
                                            Computational identification of monkeypox virus epitopes to generate a novel vaccine antigen against Mpox., PMID:39471737
                                            Systematic evaluation of the induction of efficient neutralizing antibodies by recombinant multicomponent subunit vaccines against monkeypox virus., PMID:39321566
                                            Monkeypox virus protein H3L induces injuries in human and mouse., PMID:39168969
                                            Exploring computational approaches to design mRNA Vaccine against vaccinia and Mpox viruses., PMID:39150224
                                            Identification of neutralizing antibodies against monkeypox virus using high-throughput sequencing of A35+H3L+B cells from patients with convalescent monkeypox., PMID:39002567
                                            Analysis of binding and authentic virus-neutralizing activities of immune sera induced by various monkeypox virus antigens., PMID:38829493
                                            Longitudinal viral shedding and antibody response characteristics of men with acute infection of monkeypox virus: a prospective cohort study., PMID:38802350
                                            In silico development of a novel anti-mutation, multi-epitope mRNA vaccine against MPXV variants of emerging lineage and sub-lineages by using immunoinformatics approaches., PMID:38450722
                                            Immunogenic proteins and potential delivery platforms for mpox virus vaccine development: A rapid review., PMID:37353117
                                            Multi-valent mRNA vaccines against monkeypox enveloped or mature viron surface antigens demonstrate robust immune response and neutralizing activity., PMID:37300753
                                            Development of multi-epitope vaccines against the monkeypox virus based on envelope proteins using immunoinformatics approaches., PMID:36993967
                                            Monkeypox infection elicits strong antibody and B cell response against A35R and H3L antigens., PMID:36687315
                                            Protection of rabbits and immunodeficient mice against lethal poxvirus infections by human monoclonal antibodies., PMID:23133652