Anti-PTK6 Polyclonal Antibody

Catalog No.

PHG66301

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human PTK6 (Phe191-Thr445).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Protein-tyrosine kinase 6,BRK,PTK6,Breast tumor kinase,Tyrosine-protein kinase BRK

Purification

Purified by antigen affinity column.

Accession

Q13882

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

High heterogeneity of cross-reactive immunoglobulins in multiple sclerosis presumes combining of B-cell epitopes for diagnostics: a case-control study., PMID:39669579

Molecular features and clinical implications of the heterogeneity in Chinese patients with HER2-low breast cancer., PMID:37607916

CD147 monoclonal antibody attenuates abdominal aortic aneurysm formation in angiotensin II-Infused apoE-/- mice., PMID:37393837

Kinase activity profiling reveals contribution of G-protein signaling modulator 2 deficiency to impaired regulatory T cell migration in rheumatoid arthritis., PMID:34555678

Effects of simultaneous knockdown of HER2 and PTK6 on malignancy and tumor progression in human breast cancer cells., PMID:23364537

Brk/PTK6 sustains activated EGFR signaling through inhibiting EGFR degradation and transactivating EGFR., PMID:22231447

Detection of Brk expression in non-small cell lung cancer: clinicopathological relevance., PMID:21603980

Breast tumor kinase and extracellular signal-regulated kinase 5 mediate Met receptor signaling to cell migration in breast cancer cells., PMID:20687930

PTK6 regulates IGF-1-induced anchorage-independent survival., PMID:20668531

PTK6 inhibits down-regulation of EGF receptor through phosphorylation of ARAP1., PMID:20554524

STAP-2 is phosphorylated at tyrosine-250 by Brk and modulates Brk-mediated STAT3 activation., PMID:19393627

Breast tumor kinase BRK requires kinesin-2 subunit KAP3A in modulation of cell migration., PMID:18077133

Signal transducer and activator of transcription 5b: a new target of breast tumor kinase/protein tyrosine kinase 6., PMID:17997837

Tyrosine phosphorylation of sam68 by breast tumor kinase regulates intranuclear localization and cell cycle progression., PMID:16179349

Role of breast tumour kinase in the in vitro differentiation of HaCaT cells., PMID:16086737

Regulated association of protein kinase B/Akt with breast tumor kinase., PMID:15539407

Characterization of the 5'-flanking region of the human PTK6 gene., PMID:11997104

BRK tyrosine kinase expression in a high proportion of human breast carcinomas., PMID:9266966

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