Catalog No.
VHB98604
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
Apo-E, Apolipoprotein E, APOE
Concentration
1.7 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P02649
Applications
ELISA, FuncS
Form
Liquid
Storage buffer
100 mM Pro-Ac, 20 mM Arg, pH 5.0
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
HJ15.4
Robust Serum Proteomic Signatures of APOE2., PMID:40501769
Visualization of Apolipoprotein E-Binding Amyloid Plaques in Postmortem Alzheimer's Disease Brains Using a Novel Fluorescent Probe THK-5320., PMID:40292539
A Quantitative Trait Locus for Reduced Microglial APOE Expression Associates with Reduced Cerebral Amyloid Angiopathy., PMID:40162256
Generation of novel anti-apoE monoclonal antibodies that selectively recognize apoE isoforms., PMID:38529702
Landscape of protein-protein interactions during hepatitis C virus assembly and release., PMID:38230952
Hepatitis C virus E1 recruits high-density lipoprotein to support infectivity and evade antibody recognition., PMID:38174935
Association of Apolipoprotein E Gene Polymorphism with Type 2 Diabetic Nephropathy in the Southern Chinese Population., PMID:38034901
Molecular genetic testing and measurement of levels of GPIHBP1 autoantibodies in patients with severe hypertriglyceridemia: The importance of identifying the underlying cause of hypertriglyceridemia., PMID:37981531
The E2 glycoprotein holds key residues for Mayaro virus adaptation to the urban Aedes aegypti mosquito., PMID:37018377
The impact of the PCSK-9/VLDL-Receptor axis on inflammatory cell polarization., PMID:36356495
Does the imbalance in the apolipoprotein E isoforms underlie the pathophysiological process of sporadic Alzheimer's disease?, PMID:35900209
ApoE Cascade Hypothesis in the pathogenesis of Alzheimer's disease and related dementias., PMID:35298921
Incorporation of apolipoprotein E into HBV-HCV subviral envelope particles to improve the hepatitis vaccine strategy., PMID:34750487
Hyperlipidemic myeloma, a rare form of acquired dysbetalipoproteinemia, in an HIV seropositive African female., PMID:34052205
Bibliometric analysis of the top 100 most cited studies in apolipoprotein E (ApoE) research., PMID:38449775
Kallikrein-1 Blockade Inhibits Aortic Expansion in a Mouse Model and Reduces Prostaglandin E2 Secretion From Human Aortic Aneurysm Explants., PMID:33599139
The SNPs rs429358 and rs7412 of APOE gene are association with cerebral infarction but not SNPs rs2306283 and rs4149056 of SLCO1B1 gene in southern Chinese Hakka population., PMID:32891149
25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner., PMID:32552741
Functional Characterization of Apolipoproteins in the HCV Life Cycle., PMID:30593630
A case of nephrotic syndrome showing contemporary presence of apolipoprotein E2 homozygote glomerulopathy and membranous nephropathy-like findings modified by apolipoprotein E Toyonaka., PMID:30542638
Membranous Nephropathy-Like Apolipoprotein E Deposition Disease with Apolipoprotein E Toyonaka (Ser197Cys) and a Homozygous Apolipoprotein E2/2., PMID:29692990
A fast and cost-effective method for apolipoprotein E isotyping as an alternative to APOE genotyping for patient screening and stratification., PMID:29654261
Maturation of secreted HCV particles by incorporation of secreted ApoE protects from antibodies by enhancing infectivity., PMID:28438690
Apolipoprotein E2 and E3, but Not E4, Promote Retinal Pathologic Neovascularization., PMID:28241308
[A case of diagnosing lipoprotein glomerulopathy in Russia]., PMID:28139603
Neglected but Important Role of Apolipoprotein E Exchange in Hepatitis C Virus Infection., PMID:27535051
Development of new quantitative mass spectrometry and semi-automatic isofocusing methods for the determination of Apolipoprotein E typing., PMID:26707914
Threonine modulates immune response, antioxidant status and gene expressions of antioxidant enzymes and antioxidant-immune-cytokine-related signaling molecules in juvenile blunt snout bream (Megalobrama amblycephala)., PMID:26631806
Apolipoprotein E Mediates Evasion From Hepatitis C Virus Neutralizing Antibodies., PMID:26404951
Association of Apolipoprotein E Polymorphism with Intravitreal Ranibizumab Treatment Outcomes in Age-Related Macular Degeneration., PMID:26398858
New Insights into the Understanding of Hepatitis C Virus Entry and Cell-to-Cell Transmission by Using the Ionophore Monensin A., PMID:26041282
APOE Genotype Alters Immunoglobulin Subtypes in Knock-In Mice., PMID:25737044
Role of hypervariable region 1 for the interplay of hepatitis C virus with entry factors and lipoproteins., PMID:25142595
CSF Apo-E levels associate with cognitive decline and MRI changes., PMID:24385135
Hypervariable region 1 deletion and required adaptive envelope mutations confer decreased dependency on scavenger receptor class B type I and low-density lipoprotein receptor for hepatitis C virus., PMID:24257605
Ultrastructural analysis of hepatitis C virus particles., PMID:23690609
Neocortical β-amyloid area is associated with dementia and APOE in the oldest-old., PMID:23474043
Hepatitis C virus attachment mediated by apolipoprotein E binding to cell surface heparan sulfate., PMID:22532692
High plasma level of nucleocapsid-free envelope glycoprotein-positive lipoproteins in hepatitis C patients., PMID:22290760
Hepatitis C virus epitope exposure and neutralization by antibodies is affected by time and temperature., PMID:22078164
Hepatitis C virus E1 envelope glycoprotein interacts with apolipoproteins in facilitating entry into hepatocytes., PMID:21735466
Involvement of NADPH oxidase in up-regulation of plasminogen activator inhibitor-1 and heat shock factor-1 in mouse embryo fibroblasts induced by oxidized LDL and in apolipoprotein E-deficient mice., PMID:21651452
Variants in the APOE gene are associated with improved outcome after anti-VEGF treatment for neovascular AMD., PMID:21245410
C5a receptor targeting in neointima formation after arterial injury in atherosclerosis-prone mice., PMID:20733098
Morphological characterization and fusion properties of triglyceride-rich lipoproteins obtained from cells transduced with hepatitis C virus glycoproteins., PMID:20551330
Method for the simultaneous quantitation of apolipoprotein E isoforms using tandem mass spectrometry., PMID:19653990
Apolipoprotein-mediated lipid antigen presentation in B cells provides a pathway for innate help by NKT cells., PMID:19620401
Antibodies against oxidized LDL and apolipoprotein E polymorphism in demented patients., PMID:19303604
Macrophage-mediated degradation of beta-amyloid via an apolipoprotein E isoform-dependent mechanism., PMID:19295164
For research use only. Not for human or drug use.
