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Anti-PKP1 Polyclonal Antibody

Catalog #:   PHG65701 Specific References (21) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q13835
Overview

Catalog No.

PHG65701

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human PKP1 (Asn500-Asn742).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

B6P,Plakophilin-1,Band 6 protein,PKP1

Purification

Purified by antigen affinity column.

Accession

Q13835

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • WESTERN BLOT
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with PKP1 antibody (PHG65701) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 53 kDa
    Observed MW: 53 kDa
References

Plakophilin 1 deficiency in prostatic tumours is correlated with immune cell recruitment and controls the up-regulation of cytokine expression post-transcriptionally., PMID:36380691

The value of desmosomal plaque-related markers to distinguish squamous cell carcinoma and adenocarcinoma of the lung., PMID:31809668

Searching for serum protein markers of equine squamous gastric disease using gel electrophoresis and mass spectrometry., PMID:30636330

c-Src mediated tyrosine phosphorylation of plakophilin 3 as a new mechanism to control desmosome composition in cells exposed to oxidative stress., PMID:25501895

Plakophilins, desmogleins, and pemphigus: the tail wagging the dog., PMID:24646797

Plakophilin-3 catenin associates with the ETV1/ER81 transcription factor to positively modulate gene activity., PMID:24475179

An alternative promoter of the human plakophilin-3 gene controls the expression of the new isoform PKP3b., PMID:24178805

Plakophilin-1 protects keratinocytes from pemphigus vulgaris IgG by forming calcium-independent desmosomes., PMID:24056861

Identification of the junctional plaque protein plakophilin 3 in cytoplasmic particles containing RNA-binding proteins and the recruitment of plakophilins 1 and 3 to stress granules., PMID:16407409

Expression of desmosomal proteins in squamous cell carcinomas of the skin., PMID:14744087

Alterations in desmosome size and number coincide with the loss of keratinocyte cohesion in skin with homozygous and heterozygous defects in the desmosomal protein plakophilin 1., PMID:12839569

Immunohistochemical localization of plakophilins (PKP1, PKP2, PKP3, and p0071) in primary oropharyngeal tumors: correlation with clinical parameters., PMID:12827610

Defining desmosomal plakophilin-3 interactions., PMID:12707304

Genomic amplification of the human plakophilin 1 gene and detection of a new mutation in ectodermal dysplasia/skin fragility syndrome., PMID:10951270

The function of plakophilin 1 in desmosome assembly and actin filament organization., PMID:10747098

Plakophilin 3--a novel cell-type-specific desmosomal plaque protein., PMID:10374265

Desmosomal plakophilin 2 as a differentiation marker in normal and malignant tissues., PMID:10374264

Plakophilins 1a and 1b: widespread nuclear proteins recruited in specific epithelial cells as desmosomal plaque components., PMID:9369526

The distribution of the desmosomal protein, plakophilin 1, in human skin and skin tumors., PMID:9008225

Plakophilins 2a and 2b: constitutive proteins of dual location in the karyoplasm and the desmosomal plaque., PMID:8922383

Cell type-specific desmosomal plaque proteins of the plakoglobin family: plakophilin 1 (band 6 protein)., PMID:7890138

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Anti-PKP1 Polyclonal Antibody [PHG65701]
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