Catalog No.
PHG65701
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human PKP1 (Asn500-Asn742).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
B6P,Plakophilin-1,Band 6 protein,PKP1
Purification
Purified by antigen affinity column.
Accession
Q13835
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Plakophilin 1 deficiency in prostatic tumours is correlated with immune cell recruitment and controls the up-regulation of cytokine expression post-transcriptionally., PMID:36380691
The value of desmosomal plaque-related markers to distinguish squamous cell carcinoma and adenocarcinoma of the lung., PMID:31809668
Searching for serum protein markers of equine squamous gastric disease using gel electrophoresis and mass spectrometry., PMID:30636330
c-Src mediated tyrosine phosphorylation of plakophilin 3 as a new mechanism to control desmosome composition in cells exposed to oxidative stress., PMID:25501895
Plakophilins, desmogleins, and pemphigus: the tail wagging the dog., PMID:24646797
Plakophilin-3 catenin associates with the ETV1/ER81 transcription factor to positively modulate gene activity., PMID:24475179
An alternative promoter of the human plakophilin-3 gene controls the expression of the new isoform PKP3b., PMID:24178805
Plakophilin-1 protects keratinocytes from pemphigus vulgaris IgG by forming calcium-independent desmosomes., PMID:24056861
Identification of the junctional plaque protein plakophilin 3 in cytoplasmic particles containing RNA-binding proteins and the recruitment of plakophilins 1 and 3 to stress granules., PMID:16407409
Expression of desmosomal proteins in squamous cell carcinomas of the skin., PMID:14744087
Alterations in desmosome size and number coincide with the loss of keratinocyte cohesion in skin with homozygous and heterozygous defects in the desmosomal protein plakophilin 1., PMID:12839569
Immunohistochemical localization of plakophilins (PKP1, PKP2, PKP3, and p0071) in primary oropharyngeal tumors: correlation with clinical parameters., PMID:12827610
Defining desmosomal plakophilin-3 interactions., PMID:12707304
Genomic amplification of the human plakophilin 1 gene and detection of a new mutation in ectodermal dysplasia/skin fragility syndrome., PMID:10951270
The function of plakophilin 1 in desmosome assembly and actin filament organization., PMID:10747098
Plakophilin 3--a novel cell-type-specific desmosomal plaque protein., PMID:10374265
Desmosomal plakophilin 2 as a differentiation marker in normal and malignant tissues., PMID:10374264
Plakophilins 1a and 1b: widespread nuclear proteins recruited in specific epithelial cells as desmosomal plaque components., PMID:9369526
The distribution of the desmosomal protein, plakophilin 1, in human skin and skin tumors., PMID:9008225
Plakophilins 2a and 2b: constitutive proteins of dual location in the karyoplasm and the desmosomal plaque., PMID:8922383
Cell type-specific desmosomal plaque proteins of the plakoglobin family: plakophilin 1 (band 6 protein)., PMID:7890138
For research use only. Not for human or drug use.
