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Anti-ENPP2 Polyclonal Antibody

Catalog #:   PHG65301 Specific References (31) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q13822
Overview

Catalog No.

PHG65301

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human ENPP2 (Ser637-Ile863).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

LysoPLD,Extracellular lysophospholipase D,ENPP2,Ectonucleotide pyrophosphatase/phosphodiesterase family member 2,E-NPP 2,PDNP2,Autotaxin,ATX

Purification

Purified by antigen affinity column.

Accession

Q13822

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • WESTERN BLOT
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with ENPP2 antibody (PHG65301) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 28 kDa
    Observed MW: 28 kDa
References

Rate of Decrease in Serum Autotaxin Can Predict Relapse of Type 1 Autoimmune Pancreatitis After Initial Steroid Therapy., PMID:40237760

Discovery of Imidazo[1,2-a]pyrazine Derivatives as Potent ENPP1 Inhibitors., PMID:39357030

Regulation of TGF-β1-induced fibroblast differentiation of human periodontal ligament stem cells through the mutually antagonistic action of ectonucleotide pyrophosphatase/phosphodiesterase 1 and 2., PMID:39291269

Tumour-specific activation of a tumour-blood transport improves the diagnostic accuracy of blood tumour markers in mice., PMID:38889481

Autotaxin inhibitor IOA-289 reduces gastrointestinal cancer progression in preclinical models., PMID:37550785

Decrease in serum levels of autotaxin in COVID-19 patients., PMID:36369824

Hepatocyte-Secreted Autotaxin Exacerbates Nonalcoholic Fatty Liver Disease Through Autocrine Inhibition of the PPARα/FGF21 Axis., PMID:35931383

Pain-like behavior in the collagen antibody-induced arthritis model is regulated by lysophosphatidic acid and activation of satellite glia cells., PMID:35026421

Aberrant ENPP2 expression promotes tumor progression in multiple myeloma., PMID:34847837

Effects of topical TGF-β1, TGF-β2, ATX, and LPA on IOP elevation and regulation of the conventional aqueous humor outflow pathway., PMID:33633440

Evolution and treatment of idiopathic pulmonary fibrosis., PMID:32437841

Ectonucleotide pyrophosphatase 2 (ENPP2) plays a crucial role in myogenic differentiation through the regulation by WNT/β-Catenin signaling., PMID:31805399

CSF levels of apolipoprotein C1 and autotaxin found to associate with neuropathic pain and fibromyalgia., PMID:31686904

In vivo evidence for possible up-regulating roles of lysophosphatidic acid around fertilization in rats., PMID:29162771

Inhibition of lysophosphatidic acid receptor ameliorates Sjögren's syndrome in NOD mice., PMID:28460477

Type I Interferons Function as Autocrine and Paracrine Factors to Induce Autotaxin in Response to TLR Activation., PMID:26313906

Interaction of platelet-derived autotaxin with tumor integrin αVβ3 controls metastasis of breast cancer cells to bone., PMID:25277122

Modulation of LPA receptor expression in the human brain following neurotrauma., PMID:21234797

Lysophosphatidic acid and autotaxin: emerging roles in innate and adaptive immunity., PMID:19184538

Identification of small-molecule inhibitors of autotaxin that inhibit melanoma cell migration and invasion., PMID:18852138

Monitoring the expression of purinoceptors and nucleotide-metabolizing ecto-enzymes with antibodies directed against proteins in native conformation., PMID:18404449

Positive feedback between vascular endothelial growth factor-A and autotaxin in ovarian cancer cells., PMID:18337445

Validation of an autotaxin enzyme immunoassay in human serum samples and its application to hypoalbuminemia differentiation., PMID:17963703

Production of bioactive lysophosphatidic acid by lysophospholipase D in hen egg white., PMID:17321793

Autotaxin (NPP-2) in the brain: cell type-specific expression and regulation during development and after neurotrauma., PMID:17192809

Purification and characterization of lysophospholipase D from rat brain., PMID:17071136

Cyclic phosphatidic acid is produced by autotaxin in blood., PMID:16837466

Target genes of the WNT/beta-catenin pathway in Wilms tumors., PMID:16575872

Characterization of nucleotide pyrophosphatase-5 as an oligomannosidic glycoprotein in rat brain., PMID:12927778

The nucleoside triphosphate pyrophosphohydrolase isozyme PC-1 directly promotes cartilage calcification through chondrocyte apoptosis and increased calcium precipitation by mineralizing vesicles., PMID:11764218

cDNA cloning of the human tumor motility-stimulating protein, autotaxin, reveals a homology with phosphodiesterases., PMID:7982964

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-ENPP2 Polyclonal Antibody [PHG65301]
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