Catalog No.
PHG65301
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human ENPP2 (Ser637-Ile863).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
LysoPLD,Extracellular lysophospholipase D,ENPP2,Ectonucleotide pyrophosphatase/phosphodiesterase family member 2,E-NPP 2,PDNP2,Autotaxin,ATX
Purification
Purified by antigen affinity column.
Accession
Q13822
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Rate of Decrease in Serum Autotaxin Can Predict Relapse of Type 1 Autoimmune Pancreatitis After Initial Steroid Therapy., PMID:40237760
Discovery of Imidazo[1,2-a]pyrazine Derivatives as Potent ENPP1 Inhibitors., PMID:39357030
Regulation of TGF-β1-induced fibroblast differentiation of human periodontal ligament stem cells through the mutually antagonistic action of ectonucleotide pyrophosphatase/phosphodiesterase 1 and 2., PMID:39291269
Tumour-specific activation of a tumour-blood transport improves the diagnostic accuracy of blood tumour markers in mice., PMID:38889481
Autotaxin inhibitor IOA-289 reduces gastrointestinal cancer progression in preclinical models., PMID:37550785
Decrease in serum levels of autotaxin in COVID-19 patients., PMID:36369824
Hepatocyte-Secreted Autotaxin Exacerbates Nonalcoholic Fatty Liver Disease Through Autocrine Inhibition of the PPARα/FGF21 Axis., PMID:35931383
Pain-like behavior in the collagen antibody-induced arthritis model is regulated by lysophosphatidic acid and activation of satellite glia cells., PMID:35026421
Aberrant ENPP2 expression promotes tumor progression in multiple myeloma., PMID:34847837
Effects of topical TGF-β1, TGF-β2, ATX, and LPA on IOP elevation and regulation of the conventional aqueous humor outflow pathway., PMID:33633440
Evolution and treatment of idiopathic pulmonary fibrosis., PMID:32437841
Ectonucleotide pyrophosphatase 2 (ENPP2) plays a crucial role in myogenic differentiation through the regulation by WNT/β-Catenin signaling., PMID:31805399
CSF levels of apolipoprotein C1 and autotaxin found to associate with neuropathic pain and fibromyalgia., PMID:31686904
In vivo evidence for possible up-regulating roles of lysophosphatidic acid around fertilization in rats., PMID:29162771
Inhibition of lysophosphatidic acid receptor ameliorates Sjögren's syndrome in NOD mice., PMID:28460477
Type I Interferons Function as Autocrine and Paracrine Factors to Induce Autotaxin in Response to TLR Activation., PMID:26313906
Interaction of platelet-derived autotaxin with tumor integrin αVβ3 controls metastasis of breast cancer cells to bone., PMID:25277122
Modulation of LPA receptor expression in the human brain following neurotrauma., PMID:21234797
Lysophosphatidic acid and autotaxin: emerging roles in innate and adaptive immunity., PMID:19184538
Identification of small-molecule inhibitors of autotaxin that inhibit melanoma cell migration and invasion., PMID:18852138
Monitoring the expression of purinoceptors and nucleotide-metabolizing ecto-enzymes with antibodies directed against proteins in native conformation., PMID:18404449
Positive feedback between vascular endothelial growth factor-A and autotaxin in ovarian cancer cells., PMID:18337445
Validation of an autotaxin enzyme immunoassay in human serum samples and its application to hypoalbuminemia differentiation., PMID:17963703
Production of bioactive lysophosphatidic acid by lysophospholipase D in hen egg white., PMID:17321793
Autotaxin (NPP-2) in the brain: cell type-specific expression and regulation during development and after neurotrauma., PMID:17192809
Purification and characterization of lysophospholipase D from rat brain., PMID:17071136
Cyclic phosphatidic acid is produced by autotaxin in blood., PMID:16837466
Target genes of the WNT/beta-catenin pathway in Wilms tumors., PMID:16575872
Characterization of nucleotide pyrophosphatase-5 as an oligomannosidic glycoprotein in rat brain., PMID:12927778
The nucleoside triphosphate pyrophosphohydrolase isozyme PC-1 directly promotes cartilage calcification through chondrocyte apoptosis and increased calcium precipitation by mineralizing vesicles., PMID:11764218
cDNA cloning of the human tumor motility-stimulating protein, autotaxin, reveals a homology with phosphodiesterases., PMID:7982964
For research use only. Not for human or drug use.
