Catalog No.
PHG52901
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human SLC39A6 (Lys445-Gln656).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
SLC39A6,LIV1,Zrt- and Irt-like protein 6,Zinc transporter ZIP6,ZIP-6,Estrogen-regulated protein LIV-1,Solute carrier family 39 member 6,ZIP6
Purification
Purified by antigen affinity column.
Accession
Q13433
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Zinc transporter ZnT5 is associated with epithelial mesenchymal transition via SMAD1 in breast cancer., PMID:39138630
Patritumab deruxtecan in HER2-negative breast cancer: part B results of the window-of-opportunity SOLTI-1805 TOT-HER3 trial and biological determinants of early response., PMID:38992028
Expression of cell surface zinc transporter LIV1 in triple negative breast cancer is an indicator of poor prognosis and therapy failure., PMID:38345361
Prognostic and Predictive Value of LIV1 Expression in Early Breast Cancer and by Molecular Subtype., PMID:36986799
Zinc transporter LIV1: A promising cell surface target for triple negative breast cancer., PMID:36181695
The importance of targeting signalling mechanisms of the SLC39A family of zinc transporters to inhibit endocrine resistant breast cancer., PMID:35591900
Genomic, Transcriptomic, and Proteomic Profiling of Metastatic Breast Cancer., PMID:33782032
The ZIP6/ZIP10 heteromer is essential for the zinc-mediated trigger of mitosis., PMID:32797246
Recombinant Expression of Zinc Transporter SLC39A6 and Its Functional Antibody Production., PMID:31009334
SGN-LIV1A: a novel antibody-drug conjugate targeting LIV-1 for the treatment of metastatic breast cancer., PMID:25253783
LIV-1 promotes prostate cancer epithelial-to-mesenchymal transition and metastasis through HB-EGF shedding and EGFR-mediated ERK signaling., PMID:22110740
Concordant correlation of LIV-1 and E-cadherin expression in human breast cancer cell MCF-7., PMID:18330719
For research use only. Not for human or drug use.
