Anti-PLD1 Polyclonal Antibody

Catalog No.

PHG50701

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human PLD1 (Thr725-Thr1074).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Choline phosphatase 1,PLD1,Phospholipase D1,PLD 1,Phosphatidylcholine-hydrolyzing phospholipase D1,hPLD1

Purification

Purified by antigen affinity column.

Accession

Q13393

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Innovative production of highly potent equine neutralizing antibody against Hemiscorpius lepturus scorpion venom using recombinant mPLD1 protein., PMID:39842515

Predicting a Stable Dimeric Form of the PD1-PDL1 Complex: Implications for Understanding the PD1 Activation Mechanism., PMID:37343227

A fusion protein comprising pneumococcal surface protein A and a pneumolysin derivate confers protection in a murine model of pneumococcal pneumonia., PMID:36477013

Disruption of RBMS3 suppresses PD-L1 and enhances antitumor immune activities and therapeutic effects of auranofin against triple-negative breast cancer., PMID:36414028

Inhibition of phospholipase D1 induces immunogenic cell death and potentiates cancer immunotherapy in colorectal cancer., PMID:36131027

Immunocytochemistry of phospholipase D1 and D2 in cultured cells., PMID:35963162

Sexual dimorphism in gut microbiota dictates therapeutic efficacy of intravenous immunoglobulin on radiotherapy complications., PMID:35700918

Integrin αIIbβ3 outside-in signaling activates human platelets through serine 24 phosphorylation of Disabled-2., PMID:33557943

CD4+ T Cell-Mimicking Nanoparticles Broadly Neutralize HIV-1 and Suppress Viral Replication through Autophagy., PMID:32934078

Protection against Borreliella burgdorferi infection mediated by a synthetically engineered DNA vaccine., PMID:32783701

BCALM (AC099524.1) Is a Human B Lymphocyte-Specific Long Noncoding RNA That Modulates B Cell Receptor-Mediated Calcium Signaling., PMID:32571842

Complete neutralization of the lethality of Hemiscorpius lepturus crude venom by a novel anti-recombinant phospholipase D1 IgGs., PMID:32445840

Humanized anti-CD123 antibody facilitates NK cell antibody-dependent cell-mediated cytotoxicity (ADCC) of Hodgkin lymphoma targets via ARF6/PLD-1., PMID:30647406

Regulation of the Hippo Pathway by Phosphatidic Acid-Mediated Lipid-Protein Interaction., PMID:30293781

Developing recombinant phospholipase D1 (rPLD1) toxoid from Iranian Hemiscorpius lepturus scorpion and its protective effects in BALB/c mice., PMID:29981815

Phospholipase D2 promotes disease progression of renal cell carcinoma through the induction of angiogenin., PMID:29660846

Characteristics and Lethality of a Novel Recombinant  Dermonecrotic Venom Phospholipase D from  Hemiscorpius lepturus., PMID:28335389

[Anti-PLD1 and anti-PD1 in advanced urothelial cancers: promises from early phase trials]., PMID:27712832

Phosphatidic acid-mediated activation and translocation to the cell surface of sialidase NEU3, promoting signaling for cell migration., PMID:25678627

Lipotubuloids in ovary epidermis of Ornithogalum umbellatum act as metabolons: suggestion of the name 'lipotubuloid metabolon'., PMID:25540439

TGF-β directs trafficking of the epithelial sodium channel ENaC which has implications for ion and fluid transport in acute lung injury., PMID:24324142

Chemokine unresponsiveness of chronic lymphocytic leukemia cells results from impaired endosomal recycling of Rap1 and is associated with a distinctive type of immunological anergy., PMID:23804711

Both Kdr and Flt1 play a vital role in hypoxia-induced Src-PLD1-PKCγ-cPLA(2) activation and retinal neovascularization., PMID:23319572

Morphoproteomics provides support for TGF-β pathway signaling in the osteoclastogenesis and immune dysregulation of osteolytic Langerhans cell histiocytosis., PMID:22949932

Shear stress induces cell apoptosis via a c-Src-phospholipase D-mTOR signaling pathway in cultured podocytes., PMID:22472346

β-1,3-Glucan-induced host phospholipase D activation is involved in Aspergillus fumigatus internalization into type II human pneumocyte A549 cells., PMID:21760893

Constitutive activation with overexpression of the mTORC2-phospholipase D1 pathway in uterine leiomyosarcoma and STUMP: morphoproteomic analysis with therapeutic implications., PMID:21326806

The phospholipase D1 pathway modulates macroautophagy., PMID:21266992

Phospholipase D1, but not D2, regulates protein secretion via Rho/ROCK in a Ras/Raf-independent, MEK-dependent manner in rat lacrimal gland., PMID:21212180

Gene expression profiling identifies ARSD as a new marker of disease progression and the sphingolipid metabolism as a potential novel metabolism in chronic lymphocytic leukemia., PMID:22820137

Functional role of phospholipase D (PLD) in di(2-ethylhexyl) phthalate-induced hepatotoxicity in Sprague-Dawley rats., PMID:20954081

PLD1-dependent PKCgamma activation downstream to Src is essential for the development of pathologic retinal neovascularization., PMID:20421451

The cytokine interleukin-33 mediates anaphylactic shock., PMID:19506243

Phospholipase D2 regulates endothelial permeability through cytoskeleton reorganization and occludin downregulation., PMID:19371764

Functional involvement of protein kinase C-betaII and its substrate, myristoylated alanine-rich C-kinase substrate (MARCKS), in insulin-stimulated glucose transport in L6 rat skeletal muscle cells., PMID:19252893

Phospholipase D in the human ocular surface and in pterygium., PMID:18580262

Phospholipase D in human platelets: presence of isoenzymes and participation of autocrine stimulation during thrombin activation., PMID:18432522

PLD1 and ERK2 regulate cytosolic lipid droplet formation., PMID:16723731

Phospholipase D1 regulates cell migration in a lipase activity-independent manner., PMID:16608858

Dynamics and function of phospholipase D and phosphatidic acid during phagocytosis., PMID:16497229

Peroxiredoxin II functions as a signal terminator for H2O2-activated phospholipase D1., PMID:16045763

Somatostatin increases phospholipase D activity and phosphatidylinositol 4,5-bisphosphate synthesis in clonal beta cells HIT-T15., PMID:15784846

Regulation of acetylcholine-induced phosphorylation of PLD1 in porcine tracheal smooth muscle., PMID:15591778

Phospholipase D2 localizes to the plasma membrane and regulates angiotensin II receptor endocytosis., PMID:14718562

Disruption of lipid order by short-chain ceramides correlates with inhibition of phospholipase D and downstream signaling by FcepsilonRI., PMID:12829737

Regulated secretion in chromaffin cells: an essential role for ARF6-regulated phospholipase D in the late stages of exocytosis., PMID:12438119

Phospholipase D2 is localized to the rims of the Golgi apparatus in mammalian cells., PMID:12429836

Dichotomy of Ca2+ signals triggered by different phospholipid pathways in antigen stimulation of human mast cells., PMID:11856736

Isolation and characterization of a 66-kDa protein from rat liver plasma membrane with RhoA-stimulated phospholipase D activity., PMID:11812216

Dimerization of phospholipase d isozymes., PMID:11779179

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