Catalog No.
RHJ83304
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
BAI-associated protein 2, Insulin receptor substrate p53, IRS-58, BAI1-associated protein 2, IRSp53, Insulin receptor substrate p53/p58, Fas ligand-associated factor 3, BAIAP2, FLAF3, Insulin receptor substrate protein of 53 kDa, Brain-specific angiogenesis inhibitor 1-associated protein 2, Protein BAP2, IRSp53/58
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
L117/1
Primary Central Nervous System (CNS) Lymphoma B Cell Receptors Recognize CNS Proteins., PMID:26116512
Nck adaptors, besides promoting N-WASP mediated actin-nucleation activity at pedestals, influence the cellular levels of enteropathogenic Escherichia coli Tir effector., PMID:25482634
Postsynaptic distribution of IRSp53 in spiny excitatory and inhibitory neurons., PMID:24639075
Insulin receptor substrate protein 53kDa (IRSp53) is a negative regulator of myogenic differentiation., PMID:22465711
Nonmuscle myosin IIA is required for lamellipodia formation through binding to WAVE2 and phosphatidylinositol 3,4,5-triphosphate., PMID:21184743
Insulin receptor substrate protein 53 (IRSp53) as a binding partner of antimetastasis molecule NESH, a member of Abelson interactor protein family., PMID:18480067
Regulation of dendritic spine morphogenesis by insulin receptor substrate 53, a downstream effector of Rac1 and Cdc42 small GTPases., PMID:15673667
WAVE/Scars in platelets., PMID:15280206
IRSp53 is colocalised with WAVE2 at the tips of protruding lamellipodia and filopodia independently of Mena., PMID:12734400
Distinctive tissue distribution and phosphorylation of IRSp53 isoforms., PMID:11741283
Dentatorubral-pallidoluysian atrophy protein interacts through a proline-rich region near polyglutamine with the SH3 domain of an insulin receptor tyrosine kinase substrate., PMID:10332026