Anti-NR1H3 Polyclonal Antibody

Catalog No.

PHG41701

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human NR1H3 (Asn95-Lys434).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Nuclear receptor subfamily 1 group H member 3,Oxysterols receptor LXR-alpha,NR1H3,Liver X receptor alpha,LXRA

Purification

Purified by antigen affinity column.

Accession

Q13133

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Screening of key genes involved in endometritis in cows and the regulatory role of CD83 in bovine endometrial epithelial cells., PMID:39892172

LXRα agonist differentially regulates BAFF expression and biological effects in RAW264.7 cells depending on growth status: LXRα activation and BAFF signaling in RAW264.7 cells., PMID:39632295

Interrupting tumor necrosis factor-alpha signaling prevents parenteral nutrition-associated cholestasis in mice., PMID:34664730

Genome-wide Association Study Identifies 2 New Loci Associated With Anti-NMDAR Encephalitis., PMID:34584012

Liver X Receptor α in Sciatic Nerve Exerts an Alleviating Effect on Neuropathic Pain Behaviors Induced by Crush Injury., PMID:33200264

Activation of LXRs using the synthetic agonist GW3965 represses the production of pro-inflammatory cytokines by murine mast cells., PMID:26344074

Mer signaling increases the abundance of the transcription factor LXR to promote the resolution of acute sterile inflammation., PMID:25714463

Levels of liver X receptors in testicular biopsies of patients with azoospermia., PMID:24842676

Infliximab reverses suppression of cholesterol efflux proteins by TNF-α: a possible mechanism for modulation of atherogenesis., PMID:24587984

Effects of Alisma Decoction on lipid metabolism and inflammatory response are mediated through the activation of the LXRα pathway in macrophage-derived foam cells., PMID:24504056

Activation of soluble guanylyl cyclase prevents foam cell formation and atherosclerosis., PMID:24299003

Novel effect of paeonol on the formation of foam cells: promotion of LXRα-ABCA1-dependent cholesterol efflux in macrophages., PMID:24117070

Ligation of RAGE with ligand S100B attenuates ABCA1 expression in monocytes., PMID:23523156

Exercise-associated generation of PPARγ ligands activates PPARγ signaling events and upregulates genes related to lipid metabolism., PMID:22174394

Anti-atherogenic effect of berberine on LXRalpha-ABCA1-dependent cholesterol efflux in macrophages., PMID:20506155

Tryptase promotes human monocyte-derived macrophage foam cell formation by suppressing LXRalpha activation., PMID:20139031

Tumor-mediated liver X receptor-alpha activation inhibits CC chemokine receptor-7 expression on dendritic cells and dampens antitumor responses., PMID:20037595

Liver X receptors control IgE expression in B cells., PMID:19380774

Stromal growth and epithelial cell proliferation in ventral prostates of liver X receptor knockout mice., PMID:19122149

Liver X receptor-alpha regulates proopiomelanocortin (POMC) gene transcription in the pituitary., PMID:19036902

TLR/MyD88 and liver X receptor alpha signaling pathways reciprocally control Chlamydia pneumoniae-induced acceleration of atherosclerosis., PMID:18981139

C-reactive protein induces pro- and anti-inflammatory effects, including activation of the liver X receptor alpha, on human monocytes., PMID:18327405

Liver X receptor is a key regulator of cytokine release in human monocytes., PMID:17724434

Attenuation of neuroinflammation and Alzheimer's disease pathology by liver x receptors., PMID:17563384

Expression of liver X receptor alpha in rat fetal tissues at different developmental stages., PMID:17341476

Gene expression changes in foam cells and the role of chemokine receptor CCR7 during atherosclerosis regression in ApoE-deficient mice., PMID:16537455

Placental expression of the nuclear receptors for oxysterols LXRalpha and LXRbeta during mouse and human development., PMID:15674823

Expression of the LXRalpha protein in human atherosclerotic lesions., PMID:15625283

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