Catalog No.
RHN21501
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
TrpC4, Trp-related protein 4, hTrp4, TRPC4, hTrp-4, Short transient receptor potential channel 4
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
N77/15
Direct modulation of TRPC ion channels by Gα proteins., PMID:38384797
Interactions between the Polysialylated Neural Cell Adhesion Molecule and the Transient Receptor Potential Canonical Channels 1, 4, and 5 Induce Entry of Ca2+ into Neurons., PMID:36077460
Involvement of TRPC4 and 5 Channels in Persistent Firing in Hippocampal CA1 Pyramidal Cells., PMID:32033274
3'-O-Methylorobol Inhibits the Voltage-Gated Sodium Channel Nav1.7 with Anti-Itch Efficacy in A Histamine-Dependent Itch Mouse Model., PMID:31805638
Complementary roles of KCa3.1 channels and β1-integrin during alveolar epithelial repair., PMID:26335442
Functional expression of transient receptor potential channels in human endometrial stromal cells during the luteal phase of the menstrual cycle., PMID:25820697
Involvement of TRPC channels in lung cancer cell differentiation and the correlation analysis in human non-small cell lung cancer., PMID:23840757
STIM1 controls endothelial barrier function independently of Orai1 and Ca2+ entry., PMID:23512989
TRPC channels and their splice variants are essential for promoting human ovarian cancer cell proliferation and tumorigenesis., PMID:22920441
Mass spectrometric analysis of novel phosphorylation sites in the TRPC4β channel., PMID:22847694
Orai1 determines calcium selectivity of an endogenous TRPC heterotetramer channel., PMID:22534489
TRP channel gene expression in the mouse retina., PMID:22037305
Activation of TRPC cationic channels by mercurial compounds confers the cytotoxicity of mercury exposure., PMID:21984481
Rat hypocretin/orexin neurons are maintained in a depolarized state by TRPC channels., PMID:21179559
Ca2+ paradox injury mediated through TRPC channels in mouse ventricular myocytes., PMID:20718730
Increased rhythmicity in hypertensive arterial smooth muscle is linked to transient receptor potential canonical channels., PMID:19725917
Inhibition of TRPC1/TRPC3 by PKG contributes to NO-mediated vasorelaxation., PMID:19502552
Identification of mesenchymal stem cell (MSC)-transcription factors by microarray and knockdown analyses, and signature molecule-marked MSC in bone marrow by immunohistochemistry., PMID:19228201
The specific activation of TRPC4 by Gi protein subtype., PMID:18854172
Ca2+ entry through TRPC1 channels contributes to intracellular Ca2+ dynamics and consequent glutamate release from rat astrocytes., PMID:18338793
High glucose enhances transient receptor potential channel canonical type 6-dependent calcium influx in human platelets via phosphatidylinositol 3-kinase-dependent pathway., PMID:18258814
Transient potential receptor channel 4 controls thrombospondin-1 secretion and angiogenesis in renal cell carcinoma., PMID:18021253
Immunohistochemical study on the distribution of canonical transient receptor potential channels in rat basal ganglia., PMID:17590510
Immunohistochemical study on the distribution of TRPC channels in the rat hippocampus., PMID:16580647
TRPC3 and TRPC4 associate to form a redox-sensitive cation channel. Evidence for expression of native TRPC3-TRPC4 heteromeric channels in endothelial cells., PMID:16537542
Expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells., PMID:16418302
TRPC4 is an essential component of the nonselective cation channel activated by muscarinic stimulation in mouse visceral smooth muscle cells., PMID:16404161
Identification and localization of TRPC channels in the rat kidney., PMID:16303855
Synaptic activation of transient receptor potential channels by metabotropic glutamate receptors in the lateral amygdala., PMID:16289832
Transient receptor potential protein subunit assembly and membrane distribution in human platelets., PMID:16270640
Expression and functional evaluation of transient receptor potential channel 4 in bovine corneal endothelial cells., PMID:15978249
Specific detection and semi-quantitative analysis of TRPC4 protein expression by antibodies., PMID:15965705
Cell-cell interaction underlies formation of fluid in the male reproductive tract of the rat., PMID:15851503
Plasticity of TRPC expression in arterial smooth muscle: correlation with store-operated Ca2+ entry., PMID:15561760
Canonical transient receptor potential channel 4 (TRPC4) co-localizes with the scaffolding protein ZO-1 in human fetal astrocytes in culture., PMID:15540229
Immunolocalization of TRPC channel subunits 1 and 4 in the chicken retina., PMID:14658773
Distribution of transient receptor potential channels in the rat carotid chemosensory pathway., PMID:12900933
Evidence for the expression of transient receptor potential proteins in guinea pig airway smooth muscle cells., PMID:12856738
TRPC1 store-operated cationic channel subunit., PMID:12765688