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Anti-Gephyrin Antibody (L106/93)

Catalog #:   RHK31205 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: IHC, WB
Overview

Catalog No.

RHK31205

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

MPT Mo-transferase, GPHN, GPH, Gephyrin, KIAA1385, Domain G, Domain E, MPT adenylyltransferase

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Applications

IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

L106/93

Data Image
References

High-affinity detection of biotinylated endogenous neuroligin-1 at excitatory and inhibitory synapses using a tagged knock-in mouse., PMID:40424132

Anti-NMDAR1 antibody impairs dendritic branching in immature cultured neurons., PMID:39434510

Stiff person syndrome., PMID:39174250

Stiff Person Syndrome and GAD Antibody-Spectrum Disorders., PMID:39088290

Glycine Receptor β-Targeting Autoantibodies Contribute to the Pathology of Autoimmune Diseases., PMID:38215349

Region-Specific Phosphorylation Determines Neuroligin-3 Localization to Excitatory Versus Inhibitory Synapses., PMID:38154503

Anti-Gephyrin Antibodies: A Novel Specificity in Patients With Systemic Sclerosis and Lower Bowel Dysfunction., PMID:37530745

A DARPin-based molecular toolset to probe gephyrin and inhibitory synapse biology., PMID:36314779

A Versatile Synthetic Affinity Probe Reveals Inhibitory Synapse Ultrastructure and Brain Connectivity., PMID:35421279

Expression Analyses of Cep152, a Responsible Gene Product for Autosomal Recessive Primary Microcephaly, during Mouse Brain Development., PMID:35259752

The Effect of TGF-β1 Reduced Functionality on the Expression of Selected Synaptic Proteins and Electrophysiological Parameters: Implications of Changes Observed in Acute Hepatic Encephalopathy., PMID:35163004

Stiff-person Syndrome and GAD Antibody-spectrum Disorders: GABAergic Neuronal Excitability, Immunopathogenesis and Update on Antibody Therapies., PMID:35084720

Immunohistochemical Characterization of the Nervous System of Culex pipiens (Diptera, Culicidae)., PMID:35053056

Identification of amacrine neurons with a glycinergic and GABAergic phenotype in the mouse retina., PMID:37124720

Binding of gephyrin to microtubules is regulated by its phosphorylation at Ser270., PMID:33796945

Reciprocal stabilization of glycine receptors and gephyrin scaffold proteins at inhibitory synapses., PMID:33539789

High-resolution Immunoelectron Microscopy Techniques for Revealing Distinct Subcellular Type 1 Cannabinoid Receptor Domains in Brain., PMID:33654890

Early alterations in hippocampal perisomatic GABAergic synapses and network oscillations in a mouse model of Alzheimer's disease amyloidosis., PMID:30645585

HIV gp120-induced neuroinflammation potentiates NMDA receptors to overcome basal suppression of inhibitory synapses by p38 MAPK., PMID:30520043

The role of agrin, Lrp4 and MuSK during dendritic arborization and synaptogenesis in cultured embryonic CNS neurons., PMID:30385274

Ganglion Cell Assessment in Rodents with Retinal Degeneration., PMID:29564795

In vivo transgenic expression of collybistin in neurons of the rat cerebral cortex., PMID:27804142

Mapping the connectivity of serotonin transporter immunoreactive axons to excitatory and inhibitory neurochemical synapses in the mouse limbic brain., PMID:27485750

An E3-ligase-based method for ablating inhibitory synapses., PMID:27271196

Immunostaining for Homer reveals the majority of excitatory synapses in laminae I-III of the mouse spinal dorsal horn., PMID:27185486

Clinical and Immunologic Investigations in Patients With Stiff-Person Spectrum Disorder., PMID:27065452

Inhibitory axons are targeted in hippocampal cell culture by anti-Caspr2 autoantibodies associated with limbic encephalitis., PMID:26217189

Antibodies to inhibitory synaptic proteins in neurological syndromes associated with glutamic acid decarboxylase autoimmunity., PMID:25774787

Synaptic localization of α5 GABA (A) receptors via gephyrin interaction regulates dendritic outgrowth and spine maturation., PMID:25663431

Neural circuit interactions between the dorsal raphe nucleus and the lateral hypothalamus: an experimental and computational study., PMID:24516577

Isolating specific cell and tissue compartments from 3D images for quantitative regional distribution analysis using novel computer algorithms., PMID:24487018

Encephalitis with refractory seizures, status epilepticus, and antibodies to the GABAA receptor: a case series, characterisation of the antigen, and analysis of the effects of antibodies., PMID:24462240

[The stiff-person syndrome: a brief review and report of two cases]., PMID:24317357

Regulation of α3-containing GABAA receptors in guinea-pig adrenal medullary cells by adrenal steroids., PMID:24012744

Recombinant probes for visualizing endogenous synaptic proteins in living neurons., PMID:23791193

Neurexin-1β binding to neuroligin-1 triggers the preferential recruitment of PSD-95 versus gephyrin through tyrosine phosphorylation of neuroligin-1., PMID:23770246

The adhesion protein IgSF9b is coupled to neuroligin 2 via S-SCAM to promote inhibitory synapse development., PMID:23751499

[Stiff-person syndrome and related autoantibodies]., PMID:23568987

GlyRα1, GAD65, amphiphysin, and gephyrin autoantibodies: leading or supporting roles in stiff-person disorders?, PMID:23318510

Cell type-specific inhibitory inputs to dendritic and somatic compartments of parvalbumin-expressing neocortical interneuron., PMID:23303934

Down-regulation of gephyrin and GABAA receptor subunits during epileptogenesis in the CA1 region of hippocampus., PMID:23294024

Inhibitory inputs to four types of spinocerebellar tract neurons in the cat spinal cord., PMID:22989920

Phosphorylation of gephyrin in hippocampal neurons by cyclin-dependent kinase CDK5 at Ser-270 is dependent on collybistin., PMID:22778260

Distribution of the glycine receptor β-subunit in the mouse CNS as revealed by a novel monoclonal antibody., PMID:22592841

Amacrine and bipolar inputs to midget and parasol ganglion cells in marmoset retina., PMID:22564345

Selective distribution of GABA(A) receptor subtypes in mouse spinal dorsal horn neurons and primary afferents., PMID:22522945

Neuronal profilin isoforms are addressed by different signalling pathways., PMID:22470532

Expression and subcellular distribution of gephyrin in non-neuronal tissues and cells., PMID:22270318

Inhibitory synapse dynamics: coordinated presynaptic and postsynaptic mobility and the major contribution of recycled vesicles to new synapse formation., PMID:21775594

Selective localization of collybistin at a subset of inhibitory synapses in brain circuits., PMID:21681748

Datasheet
$ 328
Product specifications
100 μg 328 1 mg 1640

Contact Information

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For research use only. Not for human or drug use.

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Anti-Gephyrin Antibody (L106/93) [RHK31205]
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