Catalog No.
PHG29001
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human HYAL1 (Phe22-Trp435).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
LuCa-1,HYAL1,Hyaluronidase-1,Hyal-1,LUCA1,Lung carcinoma protein 1,Hyaluronoglucosaminidase-1
Purification
Purified by antigen affinity column.
Accession
Q12794
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
WNT5B drives osteosarcoma stemness, chemoresistance and metastasis., PMID:38689429
An oncolytic vaccinia virus encoding hyaluronidase reshapes the extracellular matrix to enhance cancer chemotherapy and immunotherapy., PMID:38458640
Complement protein C1q stimulates hyaluronic acid degradation via gC1qR/HABP1/p32 in malignant pleural mesothelioma., PMID:37334363
Hyaluronan size alters chondrogenesis of mesenchymal stem cells cultured on tricalcium phosphate-collagen-hyaluronan scaffolds., PMID:34859573
Hyaluronidase-4 is produced by mast cells and can cleave serglycin chondroitin sulfate chains into lower molecular weight forms., PMID:31175155
Is low molecular weight hyaluronan an early indicator of disease in avian systemic sclerosis?, PMID:27135250
Targeting hyaluronic acid family for cancer chemoprevention and therapy., PMID:25081525
Hyaluronan deposition and co-localization with inflammatory cells and collagen in a murine model of fungal allergic asthma., PMID:24519432
The diagnostic efficacy of urinary survivin and hyaluronidase mRNA as urine markers in patients with bladder cancer., PMID:24133921
Hyaluronan initiates chondrogenesis mainly via CD44 in human adipose-derived stem cells., PMID:23449937
Evidence of epigenetic regulation of the tumor suppressor gene cluster flanking RASSF1 in breast cancer cell lines., PMID:22139571
HYAL1 overexpression is correlated with the malignant behavior of human breast cancer., PMID:20473947
Expression of HYAL1 and survivin RNA as diagnostic molecular markers for bladder cancer., PMID:20006858
Hyaluronic acid and HYAL-1 in prostate biopsy specimens: predictors of biochemical recurrence., PMID:19683287
Platelet-derived hyaluronidase 2 cleaves hyaluronan into fragments that trigger monocyte-mediated production of proinflammatory cytokines., PMID:19443707
Mammalian hyaluronidase induces ovarian granulosa cell apoptosis and is involved in follicular atresia., PMID:18653706
Growth factor regulation of hyaluronan synthesis and degradation in human dermal fibroblasts: importance of hyaluronan for the mitogenic response of PDGF-BB., PMID:17324121
Characterization of hyaluronan cable structure and function in renal proximal tubular epithelial cells., PMID:16900089
Evaluation of the prognostic potential of hyaluronic acid and hyaluronidase (HYAL1) for prostate cancer., PMID:12750291
Regulation of hyaluronidase activity by alternative mRNA splicing., PMID:12084718
Characterization of the murine hyaluronidase gene region reveals complex organization and cotranscription of Hyal1 with downstream genes, Fus2 and Hyal3., PMID:11929860
Elevated tissue expression of hyaluronic acid and hyaluronidase validates the HA-HAase urine test for bladder cancer., PMID:11371930
Hyaluronidase expression in human skin fibroblasts., PMID:10581201
Purification and microsequencing of hyaluronidase isozymes from human urine., PMID:9409739
Purification, cloning, and expression of human plasma hyaluronidase., PMID:9223416
For research use only. Not for human or drug use.
