Catalog No.
PHG17501
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CD300c (Gly21-Arg183).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
IgSF16,CD300c,CMRF-35,CMRF35-like molecule 6,CMRF35A1,CMRF35A,CD300C,Immunoglobulin superfamily member 16,IGSF16,CLM-6,CMRF35,CMRF35-A1,CD300 antigen-like family member C
Purification
Purified by antigen affinity column.
Accession
Q08708
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
The Combination of CD300c Antibody with PD-1 Blockade Suppresses Tumor Growth and Metastasis by Remodeling the Tumor Microenvironment in Triple-Negative Breast Cancer., PMID:40507854
Engagement of CD300c by a Novel Monoclonal Antibody Ameliorates Behavioral Deficits in a 5xFAD Mouse Model of Alzheimer's Disease., PMID:40426995
Engagement of CD300c by a novel monoclonal antibody induces the differentiation of monocytes to M1 macrophages., PMID:38159528
Recombinant CD300c-Ig fusion protein attenuates collagen-induced arthritis in mice., PMID:34021311
CD300c costimulates IgE-mediated basophil activation, and its expression is increased in patients with cow's milk allergy., PMID:29906528
Leukocyte mono-immunoglobulin-like receptor 8 (LMIR8)/CLM-6 is an FcRγ-coupled receptor selectively expressed in mouse tissue plasmacytoid dendritic cells., PMID:29844322
Antibody to CMRF35-Like Molecule 2, CD300e A Novel Biomarker Detected in Patients with Fulminant Type 1 Diabetes., PMID:27513516
CD300c is uniquely expressed on CD56 bright Natural Killer Cells and differs from CD300a upon ligand recognition., PMID:27040328
The interaction between CD300a and phosphatidylserine inhibits tumor cell killing by NK cells., PMID:23640773
CD300c is an activating receptor expressed on human monocytes., PMID:23571507
Human CD300C delivers an Fc receptor-γ-dependent activating signal in mast cells and monocytes and differs from CD300A in ligand recognition., PMID:23372157
Differential expression of CD300a/c on human TH1 and TH17 cells., PMID:22046970
Stimulation of FasL induces production of proinflammatory mediators through activation of mitogen-activated protein kinases and nuclear factor-κB in THP-1 cells., PMID:21152963
Expression and function of CD300 in NK cells., PMID:20656921
CD300a/c regulate type I interferon and TNF-alpha secretion by human plasmacytoid dendritic cells stimulated with TLR7 and TLR9 ligands., PMID:18535206
Novel human CD4+ T lymphocyte subpopulations defined by CD300a/c molecule expression., PMID:17702825
Monocytes immunoselected via the novel monocyte specific molecule, CD300e, differentiate into active migratory dendritic cells., PMID:17414321
Expression, crystallization and X-ray data collection from microcrystals of the extracellular domain of the human inhibitory receptor expressed on myeloid cells IREM-1., PMID:17329815
The crystal structure of the extracellular domain of the inhibitor receptor expressed on myeloid cells IREM-1., PMID:17275839
IREM-1 is a novel inhibitory receptor expressed by myeloid cells., PMID:15549731
CMRF-35-like molecule-1, a novel mouse myeloid receptor, can inhibit osteoclast formation., PMID:14662855
For research use only. Not for human or drug use.
