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Anti-MHC class I Antibody (N163/3)

Catalog #:   RHN14702 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: IHC, WB
Overview

Catalog No.

RHN14702

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

Class I histocompatibility antigen-like protein, MR1, MHC class I-related gene protein, Major histocompatibility complex class I-related gene protein

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Applications

IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

N163/3

Data Image
References

Nivolumab plus relatlimab in advanced melanoma: RELATIVITY-047 4-year update., PMID:40513285

Beta-2 microglobulin in lymphoma., PMID:40490112

Myositis Due to Parvovirus B19: A Case Report and Literature Review., PMID:40486395

Two major human phenotypes of MICA molecules and their differential activation to NK cells via NKG2D receptor., PMID:40458406

Immunoinformatic-driven design and evaluation of multi-epitope mRNA vaccine targeting HIV-1 gp120., PMID:40433366

NKG2D triggering hampers DNAM-1-mediated signaling in human NK cells., PMID:40421025

Effective cellular and neutralizing immunity against SARS-CoV-2 after mRNA booster vaccination is associated with pDC and B cell activation., PMID:40421016

The Validation of Antibodies Suitable for Flow Cytometric Analysis and Immunopeptidomics of Peptide-MHC Complexes in the Outbred Swiss Albino Mouse Strain., PMID:40407470

Rationale and feasibility of a rapid integral biomarker program that informs immune-oncology clinical trials: the ADVISE trial., PMID:40389374

Enhancing T cell cytotoxicity against lung cancer with an αPD-L1 protein engager and gemcitabine combination therapy., PMID:40381506

Protocol for in-plate staining of clinical peripheral blood mononuclear cell samples for high-throughput analysis via spectral flow cytometry., PMID:40347474

The Influence of the Germline HSD3B1 Adrenal-Permissive Allele (c.1100 C) on the Somatic Alteration Landscape, the Transcriptome, and Immune Cell Infiltration in Prostate Cancer., PMID:40282446

"Virtual crossmatch reveals donor-specific MICA antibodies in antibody mediated rejection: First established Indian case"., PMID:40280498

Engineering a multi-epitope chimera derived from Acinetobacter baumannii CAM87009.1 and FilF fimbriae proteins: immunogenic and antibiofilm activity., PMID:40274757

CLN-619, a MICA/B monoclonal antibody that promotes innate immune cell-mediated antitumor activity., PMID:40274283

Cross-variant immune shield: computational multiepitope vaccine design against B.617.2 to Omicron sub-lineages in SARS-CoV-2., PMID:40202023

Designing a Multi-Epitope Vaccine Candidate for Visceral Leishmaniasis Targeting Leishmania and Sand Fly Vector Antigens: An In Silico Approach., PMID:40154672

Genetic Polymorphisms in MHC Classes I and II Predict Outcomes in Metastatic Colorectal Cancer., PMID:40141198

Frizzled-7-targeting antibody-derived bifunctional protein retargets NK cells against triple-negative breast cancer cells via MICA-NKG2D axis., PMID:40021214

An epitope-directed mRNA vaccine inhibits tumor metastasis through the blockade of MICA/B α1/2 shedding., PMID:39999840

Vaccine Development T-cell (MHC-I) Epitopes Identification Against the Indian HCV Genotype: An Approach Based on Immunoinformatic., PMID:39994132

Clinico-genomic features predict distinct metastatic phenotypes in cutaneous melanoma., PMID:39975034

Detection and Quantification of Polymorphic MICA and MICB Molecules in Immunoassays: Initial Insights., PMID:39902633

Natural Killer Cell-Secreted IFN-γ and TNF-α Mediated Differentiation in Lung Stem-like Tumors, Leading to the Susceptibility of the Tumors to Chemotherapeutic Drugs., PMID:39851518

In Situ Detection of Individual Classic MHC-I Gene Products in Cancer., PMID:39804685

Novel and potent MICA/B antibody is therapeutically effective in KRAS LKB1 mutant lung cancer models., PMID:39762078

The HIP mouse and all of its organs are completely invisible to allogeneic immune cells., PMID:39758817

HLA-E: Immune Receptor Functional Mechanisms Revealed by Structural Studies., PMID:39753525

Cigarette Smoking and Symptom Burden: Baseline Results From Nine ECOG-ACRIN Cancer Clinical Trials., PMID:39746495

Circulating cytokine associations with clinical outcomes in melanoma patients treated with combination nivolumab plus ipilimumab., PMID:39699928

The Novel HDAC Inhibitor OBP-801 Promotes MHC Class I Presentation Through LMP2 Upregulation, Enhancing the PD-1-Targeting Therapy in Clear Cell Renal Cell Carcinoma., PMID:39682244

Harnessing antibody-mediated recognition of the intracellular proteome with T cell receptor-like specificity., PMID:39650646

Different MHC class I cell surface expression levels in diverse chicken lines, associations with B blood group, and proposed relationship to antigen-binding repertoire., PMID:39642749

Expression and delivery of HA1-M2e antigen using an innovative attenuated Salmonella-mediated delivery system confers promising protection against H9N2 avian influenza challenge., PMID:39631285

Long-term outcomes among patients who respond within the first year to nivolumab plus ipilimumab or nivolumab monotherapy: A pooled analysis in 935 patients., PMID:39612757

Impaired SARS-CoV-2-Specific CD8+ T Cells After Infection or Vaccination but Robust Hybrid T Cell Immunity in Patients with Multiple Myeloma., PMID:39591152

MR1 presents vitamin B6-related compounds for recognition by MR1-reactive T cells., PMID:39589872

MICA and NKG2D gene polymorphisms influence graft survival, and response to therapy in kidney transplantation., PMID:39575256

Non-RBD peptides of SARS-CoV-2 spike protein exhibit immunodominance as they elicit both innate and adaptive immune responses., PMID:39568852

Stratified analysis identifies HIF-2α as a therapeutic target for highly immune-infiltrated melanomas., PMID:39554029

Autophagy-activating aluminum hydroxide nanovaccine for enhanced antigen presentation and anti-tumor immunity., PMID:39547420

Homeostatic self-MHC-I recognition regulates anti-metastatic function of mature lung natural killer cells., PMID:39527850

Targeting RAF1 gene fusions with MEK inhibition in metastatic melanoma., PMID:39504576

Protective effect of TCR-mediated MAIT cell activation during experimental autoimmune encephalomyelitis., PMID:39468055

Characterization of Tumor-Infiltrating Lymphocyte-Derived Atypical TCRs Recognizing Breast Cancer in an MR1-Dependent Manner., PMID:39451228

Distinct Non-Human Leukocyte Antigen Antibody Signatures Correlate with Endothelial Crossmatch Status in Lung and Renal Transplant Recipients., PMID:39408890

Direct recognition of an intact foreign protein by an αβ T cell receptor., PMID:39394178

Craters on the melanoma surface facilitate tumor-immune interactions and demonstrate pathologic response to checkpoint blockade in humans., PMID:39345527

Comprehensive antitumor immune response boosted by dual inhibition of SUMOylation and MEK in MYC-expressing KRAS-mutant cancers., PMID:39334463

Converting an HLA-B27 flow assay from the BD FACSCanto to the BD FACSLyric., PMID:39287115

Datasheet
$ 328
Product specifications
100 μg 328 1 mg 1640

Contact Information

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For research use only. Not for human or drug use.

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Anti-MHC class I Antibody (N163/3) [RHN14702]
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