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Anti-NrCAM Antibody (N343/26)

Catalog #:   RHK55701 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: IHC, WB
Overview

Catalog No.

RHK55701

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

Ng-CAM-related, KIAA0343, hBravo, NRCAM, NgCAM-related cell adhesion molecule, Neuronal cell adhesion molecule, Neuronal surface protein Bravo, Nr-CAM

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Applications

IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

N343/26

Data Image
References

Neuronal cell adhesion molecule (NRCAM) variant defined by microexon skipping is an essential, antigenically distinct, and targetable proteoform in high-grade glioma., PMID:39868324

NrCAM activates the NF-κB signalling pathway by competitively binding to SUMO-1 and promotes Th17 cell differentiation in Graves' disease., PMID:39155774

Antibody-directed extracellular proximity biotinylation reveals that Contactin-1 regulates axo-axonic innervation of axon initial segments., PMID:37884508

Antibody-directed extracellular proximity biotinylation reveals Contactin-1 regulates axo-axonic innervation of axon initial segments., PMID:36945454

Investigating SH-SY5Y Neuroblastoma Cell Surfaceome as a Model for Neuronal-Targeted Novel Therapeutic Modalities., PMID:36499391

Serum molecular biomarkers in neuromyelitis optica and multiple sclerosis., PMID:35172264

Human Amniotic Epithelial Cells Alleviate a Mouse Model of Parkinson's Disease Mainly by Neuroprotective, Anti-Oxidative and Anti-Inflammatory Factors., PMID:33164162

Microfluidic production and characterization of biofunctionalized giant unilamellar vesicles for targeted intracellular cargo delivery., PMID:32987317

mRNA profiling reveals determinants of trastuzumab efficiency in HER2-positive breast cancer., PMID:25710561

Regulation of adhesion by flexible ectodomains of IgCAMs., PMID:23054071

Comparison of immune responses against FMD by a DNA vaccine encoding the FMDV/O/IRN/2007 VP1 gene and the conventional inactivated vaccine in an animal model., PMID:23001482

Nodal proteins are target antigens in Guillain-Barré syndrome., PMID:22462667

Periaxin is required for hexagonal geometry and membrane organization of mature lens fibers., PMID:21745462

CIDP - the relevance of recent advances in Schwann cell/axonal neurobiology., PMID:21504498

A glial signal consisting of gliomedin and NrCAM clusters axonal Na+ channels during the formation of nodes of Ranvier., PMID:20188654

The cell adhesion nectin-like molecules (Necl) 1 and 4 suppress the growth and tumorigenic ability of colon cancer cells., PMID:19565570

Diagnostic use of cytokeratins, CD34, and neuronal cell adhesion molecule staining in focal nodular hyperplasia and hepatic adenoma., PMID:19157505

Fast turnover of L1 adhesions in neuronal growth cones involving both surface diffusion and exo/endocytosis of L1 molecules., PMID:17538021

CAMs are stopping cancer in its metastatic tracks., PMID:16670381

Application of radioisotopes in inflammation., PMID:16611077

Increased levels of SNAP-25 and synaptophysin in the dorsolateral prefrontal cortex in bipolar I disorder., PMID:16542183

Weak effect of membrane diffusion on the rate of receptor accumulation at adhesive contacts., PMID:16169990

Gliomedin mediates Schwann cell-axon interaction and the molecular assembly of the nodes of Ranvier., PMID:16039564

Nr-CAM is a target gene of the beta-catenin/LEF-1 pathway in melanoma and colon cancer and its expression enhances motility and confers tumorigenesis., PMID:12183361

Analysis of interactions of the adhesion molecule TAG-1 and its domains with other immunoglobulin superfamily members., PMID:12139915

A neuronal inhibitory domain in the N-terminal half of agrin., PMID:11793362

Overlapping functions of the cell adhesion molecules Nr-CAM and L1 in cerebellar granule cell development., PMID:11564762

Nr-CAM expression in the developing mouse nervous system: ventral midline structures, specific fiber tracts, and neuropilar regions., PMID:11329126

The involvement of axonin-1/SC2 in mediating notochord-derived chemorepulsive activities for dorsal root ganglion neurites., PMID:10926753

A direct interaction of axonin-1 with NgCAM-related cell adhesion molecule (NrCAM) results in guidance, but not growth of commissural axons., PMID:10811834

Use of lipophilic dyes in studies of axonal pathfinding in vivo., PMID:10620782

Functional interactions of the immunoglobulin superfamily member F11 are differentially regulated by the extracellular matrix proteins tenascin-R and tenascin-C., PMID:10446214

Nr-CAM promotes neurite outgrowth from peripheral ganglia by a mechanism involving axonin-1 as a neuronal receptor., PMID:10328925

Dissection of complex molecular interactions of neurofascin with axonin-1, F11, and tenascin-R, which promote attachment and neurite formation of tectal cells., PMID:9722619

Functional cooperation of beta1-integrins and members of the Ig superfamily in neurite outgrowth induction., PMID:9465004

Cell adhesion molecules regulate guidance of dorsal root ganglion axons in the marginal zone and their invasion into the mantle layer of embryonic spinal cord., PMID:9405103

Morphogenesis of the node of Ranvier: co-clusters of ankyrin and ankyrin-binding integral proteins define early developmental intermediates., PMID:9278538

Induction of neurite outgrowth through contactin and Nr-CAM by extracellular regions of glial receptor tyrosine phosphatase beta., PMID:9049255

Chicken acidic leucine-rich EGF-like domain containing brain protein (CALEB), a neural member of the EGF family of differentiation factors, is implicated in neurite formation., PMID:9049254

Molecular composition of the node of Ranvier: identification of ankyrin-binding cell adhesion molecules neurofascin (mucin+/third FNIII domain-) and NrCAM at nodal axon segments., PMID:8947556

Neurofascin induces neurites by heterophilic interactions with axonal NrCAM while NrCAM requires F11 on the axonal surface to extend neurites., PMID:8922386

Structural features of a close homologue of L1 (CHL1) in the mouse: a new member of the L1 family of neural recognition molecules., PMID:8921253

Binding between the neural cell adhesion molecules axonin-1 and Nr-CAM/Bravo is involved in neuron-glia interaction., PMID:7490283

Axonin-1, Nr-CAM, and Ng-CAM play different roles in the in vivo guidance of chick commissural neurons., PMID:7541632

Developmental changes in epitope accessibility as an indicator of multiple states of an immunoglobulin-like neural cell adhesion molecule., PMID:7608337

Expression of four immunoglobulin superfamily adhesion molecules (L1, Nr-CAM/Bravo, neurofascin/ABGP, and N-CAM) in the developing mouse spinal cord., PMID:7706555

Induction of axonal growth by heterophilic interactions between the cell surface recognition proteins F11 and Nr-CAM/Bravo., PMID:8274278

Homophilic and heterophilic binding activities of Nr-CAM, a nervous system cell adhesion molecule., PMID:1527169

Bravo/Nr-CAM is closely related to the cell adhesion molecules L1 and Ng-CAM and has a similar heterodimer structure., PMID:1512296

Structure of the axonal surface recognition molecule neurofascin and its relationship to a neural subgroup of the immunoglobulin superfamily., PMID:1377696

Datasheet
$ 328
Product specifications
100 μg 328 1 mg 1640

Contact Information

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For research use only. Not for human or drug use.

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Anti-NrCAM Antibody (N343/26) [RHK55701]
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