Catalog No.
RHN13901
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
HASPIN, GSG2, Serine/threonine-protein kinase haspin, Germ cell-specific gene 2 protein, Haploid germ cell-specific nuclear protein kinase, H-haspin
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
N128A/2
Effects and mechanisms of GSG2 in esophageal cancer progression., PMID:35939116
GSG2 Promotes Development and Predicts Poor Prognosis of Ovarian Cancer., PMID:33500663
HASPIN is involved in the progression of gallbladder carcinoma., PMID:31987787
Haspin knockdown can inhibit progression and development of pancreatic cancer in vitro and vivo., PMID:31493385
OTSSP167 Abrogates Mitotic Checkpoint through Inhibiting Multiple Mitotic Kinases., PMID:27082996
Haspin inhibitors reveal centromeric functions of Aurora B in chromosome segregation., PMID:23071152
Histone H3 Thr-3 phosphorylation by Haspin positions Aurora B at centromeres in mitosis., PMID:20705812
Phosphorylation of histone H3 at Thr3 is part of a combinatorial pattern that marks and configures mitotic chromatin., PMID:19622635
Identification of small molecule inhibitors of the mitotic kinase haspin by high-throughput screening using a homogeneous time-resolved fluorescence resonance energy transfer assay., PMID:18978305
The kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignment., PMID:15681610
Identification and characterization of a haploid germ cell-specific nuclear protein kinase (Haspin) in spermatid nuclei and its effects on somatic cells., PMID:10358056
For research use only. Not for human or drug use.
