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Anti-C1QBP Polyclonal Antibody

Catalog #:   PHG11201 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q07021
Overview

Catalog No.

PHG11201

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human C1QBP (Thr76-Gln282).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Hyaluronan-binding protein 1,SF2AP32,C1QBP,gC1q-R protein,SF2P32,Glycoprotein gC1qBP,Complement component 1 Q subcomponent-binding protein,mitochondrial,ASF/SF2-associated protein p32,GC1QBP,HABP1,p33,C1qBP,Mitochondrial matrix protein p32

Purification

Purified by antigen affinity column.

Accession

Q07021

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • WESTERN BLOT
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with C1QBP antibody (PHG11201) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 26 kDa
    Observed MW: 26 kDa
References

Macrophages Promote Atherosclerosis Development by Inhibiting CD8T Cell Apoptosis., PMID:39345351

Targeting tumor cell-to-macrophage communication by blocking Vtn-C1qbp interaction inhibits tumor progression via enhancing macrophage phagocytosis., PMID:38773982

Complement protein C1q stimulates hyaluronic acid degradation via gC1qR/HABP1/p32 in malignant pleural mesothelioma., PMID:37334363

gC1qR: A New Target for Cancer Immunotherapy., PMID:36776869

gC1qR/C1qBP/HABP-1: Structural Analysis of the Trimeric Core Region, Interactions With a Novel Panel of Monoclonal Antibodies, and Their Influence on Binding to FXII., PMID:35865516

An approach to p32/gC1qR/HABP1: a multifunctional protein with an essential role in cancer., PMID:35441886

Identification of Mitofusin 1 and Complement Component 1q Subcomponent Binding Protein as Mitochondrial Targets in Systemic Lupus Erythematosus., PMID:35128841

gC1qR Antibody Can Modulate Endothelial Cell Permeability in Angioedema., PMID:34494203

SARS-CoV-2 proteins regulate inflammatory, thrombotic and diabetic responses in human arterial fibroblasts., PMID:33895357

Heterozygous P32/C1QBP/HABP1 Polymorphism rs56014026 Reduces Mitochondrial Oxidative Phosphorylation and Is Expressed in Low-grade Colorectal Carcinomas., PMID:33628739

Role of C1QBP/p32 and its Therapeutic Potential in Breast Carcinoma and other Cancers., PMID:33390103

Therapeutic Zfra4-10 or WWOX7-21 Peptide Induces Complex Formation of WWOX with Selective Protein Targets in Organs that Leads to Cancer Suppression and Spleen Cytotoxic Memory Z Cell Activation In Vivo., PMID:32764489

Autoantigens in the trabecular meshwork and glaucoma-specific alterations in the natural autoantibody repertoire., PMID:32140226

Porcine reproductive and respiratory syndrome virus infection promotes C1QBP secretion to enhance inflammatory responses., PMID:31928703

The C1q Receptors: Focus on gC1qR/p33 (C1qBP, p32, HABP-1)1., PMID:31744753

Phylogenetically Defined Isoforms of Listeria monocytogenes Invasion Factor InlB Differently Activate Intracellular Signaling Pathways and Interact with the Receptor gC1q-R., PMID:31450632

Complement component 1q subcomponent binding protein in the brain of the rat., PMID:30872665

Dynamic Hyaluronan drives liver endothelial cells towards angiogenesis., PMID:29890947

A novel small molecule inhibitor of p32 mitochondrial protein overexpressed in glioma., PMID:29047383

C1QBP is upregulated in colon cancer and binds to apolipoprotein A-I., PMID:28565870

Cytoadhesion to gC1qR through Plasmodium falciparum Erythrocyte Membrane Protein 1 in Severe Malaria., PMID:27835682

Antibody neutralization of cell-surface gC1qR/HABP1/SF2-p32 prevents lamellipodia formation and tumorigenesis., PMID:27363031

Identification of the gC1qR sites for the HIV-1 viral envelope protein gp41 and the HCV core protein: Implications in viral-specific pathogenesis and therapy., PMID:27111569

ADAM28 is expressed by epithelial cells in human normal tissues and protects from C1q-induced cell death., PMID:26918856

Disrupted hyaluronan binding protein 1 (HABP1) expression: one of the key mediator for ovarian dysfunction in polycystic ovary rat., PMID:25300617

cC1qR/CR and gC1qR/p33: observations in cancer., PMID:25044096

Autophagic vacuolation induced by excess ROS generation in HABP1/p32/gC1qR overexpressing fibroblasts and its reversal by polymeric hyaluronan., PMID:24205125

Occlusal trauma accelerates attachment loss at the onset of experimental periodontitis in rats., PMID:23808820

Lectin-dependent enhancement of Ebola virus infection via soluble and transmembrane C-type lectin receptors., PMID:23573288

Gram-positive bacteria as an antigen topically applied into gingival sulcus of immunized rat accelerates periodontal destruction., PMID:23137272

gC1qR expression in normal and pathologic human tissues: differential expression in tissues of epithelial and mesenchymal origin., PMID:22638269

Interaction of HmC1q with leech microglial cells: involvement of C1qBP-related molecule in the induction of cell chemotaxis., PMID:22356764

The formation of immune complexes is involved in the acute phase of periodontal destruction in rats., PMID:22283745

The multicompartmental p32/gClqR as a new target for antibody-based tumor targeting strategies., PMID:21156793

HIV gp41 engages gC1qR on CD4+ T cells to induce the expression of an NK ligand through the PIP3/H2O2 pathway., PMID:20617170

Activation of the plasma kallikrein-kinin system on human lung epithelial cells., PMID:20536386

PPAR-delta senses and orchestrates clearance of apoptotic cells to promote tolerance., PMID:19838202

Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans., PMID:19029902

Evidence for a novel chemotactic C1q domain-containing factor in the leech nerve cord., PMID:18952286

Human p32 is a novel FOXC1-interacting protein that regulates FOXC1 transcriptional activity in ocular cells., PMID:18676636

Expression of complement components and inhibitors on platelet microparticles., PMID:18432523

Novel tyrosine phosphorylated and cardiolipin-binding protein CLPABP functions as mitochondrial RNA granule., PMID:18191643

The exosporium of B. cereus contains a binding site for gC1qR/p33: implication in spore attachment and/or entry., PMID:17892212

HCV core protein interaction with gC1q receptor inhibits Th1 differentiation of CD4+ T cells via suppression of dendritic cell IL-12 production., PMID:17881511

Classical pathway complement activation on human endothelial cells., PMID:17173972

Blood platelets activate the classical pathway of human complement., PMID:16961611

gC1qR/p33 serves as a molecular bridge between the complement and contact activation systems and is an important catalyst in inflammation., PMID:16893067

Acetylated Tat regulates human immunodeficiency virus type 1 splicing through its interaction with the splicing regulator p32., PMID:16537587

gC1q receptor ligation selectively down-regulates human IL-12 production through activation of the phosphoinositide 3-kinase pathway., PMID:16177118

Chemotaxis of human monocyte-derived dendritic cells to complement component C1q is mediated by the receptors gC1qR and cC1qR., PMID:16140380

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-C1QBP Polyclonal Antibody [PHG11201]
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