Catalog No.
PHG10401
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human FMOD (Gln19-Ile376).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Collagen-binding 59 kDa protein,KSPG fibromodulin,FMOD,FM,Fibromodulin,Keratan sulfate proteoglycan fibromodulin,SLRR2E
Purification
Purified by antigen affinity column.
Accession
Q06828
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Tumor-matched and unmatched cancer associated fibroblasts exhibit differential effect on proliferation and FMOD and MMP9 gene expression in head and neck squamous cell carcinoma cells when cocultured in spheroids., PMID:38822309
A Novel Fibromodulin Antagonist Peptide RP4 Exerts Antitumor Effects on Colorectal Cancer., PMID:36986805
A novel ADC targeting cell surface fibromodulin in a mouse model of triple-negative breast cancer., PMID:35982394
The Association of Cell Surface Fibromodulin Expression and Bladder Carcinoma., PMID:34247360
OPG-Fc treatment partially rescues low bone mass phenotype in mature Bgn/Fmod deficient mice but is deleterious to the young mouse skeleton., PMID:32950603
Wnt/β-Catenin Pathway-Regulated Fibromodulin Expression Is Crucial for Breast Cancer Metastasis and Inhibited by Aspirin., PMID:31824307
Monoclonal and Polyclonal Antibodies Specific to Human Fibromodulin., PMID:31457049
Anchored Fibromodulin as a Novel Target in Chronic Lymphocytic Leukemia: Diagnostic and Therapeutic Implications., PMID:31182687
Catabolism of Fibromodulin in Developmental Rudiment and Pathologic Articular Cartilage Demonstrates Novel Roles for MMP-13 and ADAMTS-4 in C-terminal Processing of SLRPs., PMID:30700002
Analysis of the cancer genome atlas (TCGA) database identifies an inverse relationship between interleukin-13 receptor α1 and α2 gene expression and poor prognosis and drug resistance in subjects with glioblastoma multiforme., PMID:29168083
Type 2 diabetes alters mesenchymal stem cell secretome composition and angiogenic properties., PMID:27641937
Immunolocalization and distribution of proteoglycans in carious dentine., PMID:26435422
Melanocyte pigmentation inversely correlates with MCP-1 production and angiogenesis-inducing potential., PMID:25406462
Small leucine-rich proteoglycans exhibit unique spatiotemporal expression profiles during cardiac valve development., PMID:24272803
A proline/arginine-rich end leucine-rich repeat protein (PRELP) variant is uniquely expressed in chronic lymphocytic leukemia cells., PMID:23826326
Reduced decorin, fibromodulin, and transforming growth factor-β3 in deep dermis leads to hypertrophic scarring., PMID:22079916
Small leucine-rich proteoglycans, decorin and fibromodulin, are reduced in postburn hypertrophic scar., PMID:21518082
Silencing of ROR1 and FMOD with siRNA results in apoptosis of CLL cells., PMID:20813009
Disruption of T cell suppression in chronic lymphocytic leukemia by CD200 blockade., PMID:18838168
Fragmentation of decorin, biglycan, lumican and keratocan is elevated in degenerate human meniscus, knee and hip articular cartilages compared with age-matched macroscopically normal and control tissues., PMID:18620607
An immunohistochemical study of the extracellular matrix of entheses associated with the human pisiform bone., PMID:18399959
The extracellular matrix and inflammation: fibromodulin activates the classical pathway of complement by directly binding C1q., PMID:16046396
Colocalization of the collagen-binding proteoglycans decorin, biglycan, fibromodulin and lumican with different cells in human gingiva., PMID:15613083
[Immunohistochemical localization and expression of fibromodulin in the periodontium]., PMID:14642103
Immunohistochemical localization of fibromodulin in the periodontium during cementogenesis and root formation in the rat molar., PMID:12941075
Distribution of cartilage molecules in the developing mouse joint., PMID:10601736
Age-related changes in fibromodulin and lumican in human intervertebral discs., PMID:10488504
Characterization of the macromolecular components of the articular cartilage surface., PMID:9782536
Human granulation-tissue fibroblasts show enhanced proteoglycan gene expression and altered response to TGF-beta 1., PMID:8955672
Changes with age in the structure of fibromodulin in human articular cartilage., PMID:8895216
Proteoglycans of human rotator cuff tendons., PMID:8764859
Large and small proteoglycans of osteoarthritic and rheumatoid articular cartilage., PMID:7538297
Inhibition of human fibroblast adhesion by cartilage surface proteoglycans., PMID:7980677
Non-collagenous protein screening in the human chondrodysplasias: link proteins, cartilage oligomeric matrix protein (COMP), and fibromodulin., PMID:8030664
Repair of intra-membranous bone fractures and defects in rats. Immunolocalization of bone and cartilage proteins and proteoglycans., PMID:2019654
For research use only. Not for human or drug use.
