Catalog No.
RHG35101
Species reactivity
Human, Mouse, Rat
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
Ankyrin-3, ANK3, ANK-3, Ankyrin-G
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Applications
IB, ICC, IF
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
N106/20
Reduced expression of Ankyrin-G and E-cadherin in duodenal mucosal biopsy of subjects with celiac disease., PMID:38324966
Complement-membrane regulatory proteins are absent from the nodes of Ranvier in the peripheral nervous system., PMID:37875972
Microglial synaptic pruning on axon initial segment spines of dentate granule cells: Sexually dimorphic effects of early-life stress and consequences for adult fear response., PMID:33890333
Dynamic Regulation of Synaptopodin and the Axon Initial Segment in Retinal Ganglion Cells During Postnatal Development., PMID:31417359
A constitutively-active IKK-complex at the axon initial segment., PMID:29079505
Aging Does Not Affect Axon Initial Segment Structure and Somatic Localization of Tau Protein in Hippocampal Neurons of Fischer 344 Rats., PMID:28785724
CK2-regulated schwannomin-interacting protein IQCJ-SCHIP-1 association with AnkG contributes to the maintenance of the axon initial segment., PMID:25950943
Striatins as plaque molecules of zonulae adhaerentes in simple epithelia, of tessellate junctions in stratified epithelia, of cardiac composite junctions and of various size classes of lateral adherens junctions in cultures of epithelia- and carcinoma-derived cells., PMID:25501894
CK2 accumulation at the axon initial segment depends on sodium channel Nav1., PMID:25109776
A unique ion channel clustering domain on the axon initial segment of mammalian neurons., PMID:24477962
Ankyrin-B structurally defines terminal microdomains of peripheral somatosensory axons., PMID:22886464
Active vaccination with ankyrin G reduces β-amyloid pathology in APP transgenic mice., PMID:22688190
Anti-GD1a antibodies activate complement and calpain to injure distal motor nodes of Ranvier in mice., PMID:20513658
Heat opens axon initial segment sodium channels: a febrile seizure mechanism?, PMID:19743470
Polarized distribution of ion channels within microdomains of the axon initial segment., PMID:17111377
A common ankyrin-G-based mechanism retains KCNQ and NaV channels at electrically active domains of the axon., PMID:16525039
Expression of Nav1.6 sodium channels by Schwann cells at neuromuscular junctions: role in the motor endplate disease phenotype., PMID:16078241
Elevated ankyrin G in a plexiform neurofibroma and neuromas associated with pain., PMID:15519868
AMPA/kainate receptors in mouse spinal cord cell-specific display of receptor subunits by oligodendrocytes and astrocytes and at the nodes of Ranvier., PMID:12594733
Interaction of the Nav1.2a subunit of the voltage-dependent sodium channel with nodal ankyrinG. In vitro mapping of the interacting domains and association in synaptosomes., PMID:12036953
Structural requirements for interaction of sodium channel beta 1 subunits with ankyrin., PMID:11997395
Ankyrin G and voltage gated sodium channels colocalize in human neuroma--key proteins of membrane remodeling after axonal injury., PMID:11950515
Identification of Ank(G107), a muscle-specific ankyrin-G isoform., PMID:11796721
betaIV spectrin, a new spectrin localized at axon initial segments and nodes of ranvier in the central and peripheral nervous system., PMID:11086001
Expression of sodium channel SNS/PN3 and ankyrin(G) mRNAs in the trigeminal ganglion after inferior alveolar nerve injury in the rat., PMID:10915577
Clustering of neuronal sodium channels requires contact with myelinating Schwann cells., PMID:10739572
Isoforms of ankyrin-3 that lack the NH2-terminal repeats associate with mouse macrophage lysosomes., PMID:9060470
For research use only. Not for human or drug use.
