Catalog No.
RHF65202
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
ASIC1, Amiloride-sensitive cation channel 2, neuronal, BNaC2, Brain sodium channel 2, ACCN2, Acid-sensing ion channel 1, BNAC2
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
N271/28
Upregulation of Acid-Sensing Ion Channel 1a in the Anterior Cingulate Cortex by TNF-α/NF-κB Pathway Contributes to Diabetes-Related Pain., PMID:40131336
Structure and analysis of nanobody binding to the human ASIC1a ion channel., PMID:34319232
Assessment of Pediatric Optic Neuritis Visual Acuity Outcomes at 6 Months., PMID:33057592
Differential Expression of Acid - Sensing Ion Channels in Mouse Primary Afferents in Naïve and Injured Conditions., PMID:32508593
Selection of an ASIC1a-blocking combinatorial antibody that protects cells from ischemic death., PMID:30042215
Neuroprotective Effects of Psalmotoxin-1, an Acid-Sensing Ion Channel (ASIC) Inhibitor, in Ischemia Reperfusion in Mouse Eyes., PMID:29595330
Expression and purification of the alpha subunit of the epithelial sodium channel, ENaC., PMID:26394093
Interleukin-6 enhances acid-induced apoptosis via upregulating acid-sensing ion channel 1a expression and function in rat articular chondrocytes., PMID:26359543
Atomic force microscopy imaging reveals the formation of ASIC/ENaC cross-clade ion channels., PMID:26032502
Acid-sensing ion channel 1 and nitric oxide synthase are in adjacent layers in the wall of rat and human cerebral arteries., PMID:25462386
Acid-sensing ion channels are involved in epithelial Na+ uptake in the rainbow trout Oncorhynchus mykiss., PMID:24898589
Human odontoblasts express transient receptor protein and acid-sensing ion channel mechanosensor proteins., PMID:20836083
Demonstration of a direct interaction between sigma-1 receptors and acid-sensing ion channels., PMID:20371317
Sour ageusia in two individuals implicates ion channels of the ASIC and PKD families in human sour taste perception at the anterior tongue., PMID:19812697
ASIC1 contributes to pulmonary vascular smooth muscle store-operated Ca(2+) entry., PMID:19482897
Distribution, subcellular localization and ontogeny of ASIC1 in the mammalian central nervous system., PMID:12509480
Rabbit retinal neurons and glia express a variety of ENaC/DEG subunits., PMID:12055080
Functional implications of the localization and activity of acid-sensitive channels in rat peripheral nervous system., PMID:11842212
Increased acid-sensing ion channel ASIC-3 in inflamed human intestine., PMID:11507351
For research use only. Not for human or drug use.
