Catalog No.
PHF90601
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human PLCB3 (Asp318-Lys468).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Phospholipase C-beta-3,PLC-beta-3,1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3,Phosphoinositide phospholipase C-beta-3,PLCB3
Purification
Purified by antigen affinity column.
Accession
Q01970
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Cetuximab inhibits colorectal cancer development through inactivating the Wnt/β-catenin pathway and modulating PLCB3 expression., PMID:38724565
CAPE suppresses migration and invasion of prostate cancer cells via activation of non-canonical Wnt signaling., PMID:27191743
Short Stat5-interacting peptide derived from phospholipase C-β3 inhibits hematopoietic cell proliferation and myeloid differentiation., PMID:21949826
A(1) adenosine receptor-mediated PKC and p42/p44 MAPK signaling in mouse coronary artery smooth muscle cells., PMID:19592614
Sphingosine 1-phosphate-induced signal transduction in cat esophagus smooth muscle cells., PMID:16511346
Expression of phospholipase C beta family isoenzymes in C2C12 myoblasts during terminal differentiation., PMID:15174099
1alpha,25(OH)2D3 causes a rapid increase in phosphatidylinositol-specific PLC-beta activity via phospholipase A2-dependent production of lysophospholipid., PMID:12798493
Subcellular localization of phospholipase C isoforms in vascular smooth muscle., PMID:12176394
Immunocytochemical evidence for co-expression of Type III IP3 receptor with signaling components of bitter taste transduction., PMID:11346454
Bradykinin, but not muscarinic, inhibition of M-current in rat sympathetic ganglion neurons involves phospholipase C-beta 4., PMID:11050147
Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction., PMID:10669417
Ggamma13 colocalizes with gustducin in taste receptor cells and mediates IP3 responses to bitter denatonium., PMID:10570481
Activation of phospholipase C-beta1 via Galphaq/11 during calcium mobilization by calcitonin gene-related peptide., PMID:9685362
Gastrin induces IP3 formation through phospholipase C gamma 1 and pp60c-src kinase., PMID:9437736
Synthetic peptides containing a BXBXXXB(B) motif activate phospholipase C-beta1., PMID:9307015
Distribution of phospholipase C isozymes in normal human lung tissue and their immunohistochemical localization., PMID:8878798
For research use only. Not for human or drug use.
